公开(公告)号：US07236620B1

公开(公告)日：2007-06-26

申请号：US10600783

申请日：2003-06-20

申请人： Metin N. Gurcan

发明人： Metin N. Gurcan

IPC分类号： G06K9/00

CPC分类号： G06K9/46 ,  G06T7/0012 ,  G06T2207/30028

摘要： This invention provides a method for detecting abnormalities in medical images, particularly for the detection of polyps in the colon from computed tomography imagery. Specifically a set of colon masks is input to a detector where summations over spherical volumes with two different radii are computed. Abnormalities are detected based on the ratio of spherical summation values computed for every pixel location.

摘要翻译： 本发明提供一种用于检测医学图像异常的方法，特别是用于从计算机断层摄影图像检测结肠息肉。 具体地，一组结肠掩模被输入到检测器，其中计算具有两个不同半径的球形体积上的求和。 基于为每个像素位置计算的球面求和值的比率来检测异常。

公开(公告)号：US20030110178A1

公开(公告)日：2003-06-12

申请号：US10292514

申请日：2002-11-13

申请人： icad, inc.

发明人： Kevin S. Woods ,  Maha Yousef Sallam ,  Greg Gustafson

IPC分类号： G06F007/00

CPC分类号： G06F19/321

摘要： A method and system for tracking medical images and associated digital images for diagnostic evaluation. The system includes a scanner for digitizing one or more medical images defining a case to thereby produce one or more digitized medical images and for reading a machine-readable tracking identifier attached to each medical image of the case. A server associates the tracking identifier with one or more digitized medical images and one or more computer-aided diagnostic (CAD) images, wherein the one or more CAD images correspond to the one or more digitized medical images that are processed using a CAD algorithm. The system stores the associated tracking identifier, the one or more digitized medical images, and the one or more CAD images in a storage device. The server receives and processes a medical image request including the tracking identifier to retrieve at least one of the one or more digitized medical images or the one or more CAD images from the storage device using the tracking identifier.

摘要翻译： 一种用于跟踪医学图像和相关数字图像进行诊断评估的方法和系统。 该系统包括用于数字化定义病例的一个或多个医学图像的扫描器，从而产生一个或多个数字化的医学图像，并且用于读取附接到病例的每个医学图像的机器可读跟踪标识符。 服务器将跟踪标识符与一个或多个数字化医学图像和一个或多个计算机辅助诊断（CAD）图像相关联，其中一个或多个CAD图像对应于使用CAD算法处理的一个或多个数字化医学图像。 系统将相关联的跟踪标识符，一个或多个数字化医学图像以及一个或多个CAD图像存储在存储设备中。 服务器接收并处理包括跟踪标识符的医学图像请求，以使用跟踪标识符从存储设备检索一个或多个数字化医学图像或一个或多个CAD图像中的至少一个。

公开(公告)号：US11205265B2

公开(公告)日：2021-12-21

申请号：US16693105

申请日：2019-11-22

申请人： iCAD, Inc.

发明人： Per Frans Leonard Hall ,  Mikael Emil Dan Eriksson ,  Kourosh Jafari-Khouzani ,  Senthil Periaswamy

IPC分类号： G06K9/00 ,  A61B6/04 ,  G06T7/00 ,  G16H50/30 ,  G16H30/20

摘要： This invention provides a system and method for assessing risk of a breast cancer diagnosis based upon imagery of tissue and (optionally) other patient-related factors. A CAD (or similar) system analyzes the imagery and generates a plurality of numerical feature values. An assessment module receives inputs from patient factors and history and computes the risk based upon the feature values and the patient factors and history. A masking module receives inputs from the patient factors and history, and computes the risk of having a cancer, which cancer is otherwise characterized by a low probability of detection, based upon the feature values and the patient factors and history. A recall module receives inputs from the assessment module and the masking assessment module, and generates a computer-aided indication of a clinical follow-up by the patient. Results of assessment(s) can be displayed to the clinician and/or patient using a graphical interface display.

公开(公告)号：US09311705B1

公开(公告)日：2016-04-12

申请号：US13341528

申请日：2011-12-30

申请人： Sergey Fotin ,  Senthil Periaswamy

发明人： Sergey Fotin ,  Senthil Periaswamy

IPC分类号： G06K9/00 ,  G06T7/00

CPC分类号： G06T7/0014 ,  G06T7/74 ,  G06T2207/10088 ,  G06T2207/30081 ,  G06T7/0012 ,  A61B6/12

摘要： This invention provides a system, method and computer-readable medium for detecting and localizing organs and other regions of interest in medical image data provided by a medical imaging procedure using gradient template information with respect to an example of the imaged organ and cross-correlation techniques to generate object detection information. In an embodiment, the detection and localization process/processor receives a plurality of gradient templates and employers a template with the closest matching cross-correlation to the gradient of the organ in the medical image.

摘要翻译： 本发明提供了一种系统，方法和计算机可读介质，用于检测和定位由医学成像程序提供的医学图像数据中的器官和其他感兴趣区域，所述医学图像数据使用关于成像器官和互相关技术的示例的梯度模板信息 生成对象检测信息。 在一个实施例中，检测和定位处理/处理器接收多个梯度模板和雇主具有与医学图像中器官的梯度最接近的匹配互相关的模板。

公开(公告)号：US08340388B2

公开(公告)日：2012-12-25

申请号：US12611413

申请日：2009-11-03

申请人： John E. Rosenstengel

发明人： John E. Rosenstengel

IPC分类号： G06K9/00 ,  A61B6/04

CPC分类号： G06T7/0012 ,  G06T2207/10116 ,  G06T2207/30068 ,  G06T2207/30096

摘要： Systems, computer-readable media, methods, and a medical imaging apparatus for improving the automated detection of suspicious regions of interest in x-ray images of anatomical organs under study are disclosed. Noise effects in x-ray images are suppressed to predetermined levels by filtering the original x-ray images and then combining the original images with the filtered images in such a way that the predetermined noise value is met. The resulting modified x-ray images then may be analyzed to automatically detect suspected breast microcalcifications or other suspicious regions of interest. In addition, three-dimensional digital images of anatomical organs may be computed from a plurality of such modified x-ray images of an anatomical organ taken from different angles, as in CT imaging, and the three-dimensional digital images may be processed to automatically detect suspicious regions of interest.

摘要翻译： 公开了用于改善在研究的解剖器官的x射线图像中的可疑感兴趣区域的自动检测的系统，计算机可读介质，方法和医学成像装置。 通过对原始X射线图像进行滤波，然后将原始图像与滤波图像组合，使得满足预定的噪声值，将x射线图像中的噪声效应抑制到预定水平。 然后可以分析所得到的修改的X射线图像以自动检测怀疑的乳腺微钙化或其他可疑的感兴趣区域。 此外，解剖器官的三维数字图像可以从CT成像中从不同角度取得的解剖器官的多个这样的修改的X射线图像计算，并且三维数字图像可以被自动处理 检测可疑的感兴趣区域。

公开(公告)号：US08275181B2

公开(公告)日：2012-09-25

申请号：US11919938

申请日：2006-05-08

申请人： Naira Muradyan ,  Andreas Muehler

发明人： Naira Muradyan ,  Andreas Muehler

IPC分类号： G06K9/00

CPC分类号： G06T7/0012 ,  G06T2207/30004

摘要： A method for performing a high-resolution pharmacokinetic analysis for calculation of tissue parameters for a fast-enhancing tissue enables medical personnel to accurately determine pharmacokinetic parameters in fast-enhancing tissues. The method includes obtaining mask image data of the tissue when it is in a steady state condition, obtaining a time series of image data of the tissue when the contrast agent is flowing in the tissue, and increasing a spatial resolution of the time series of image data using the mask image data to obtain a time series of increased spatial resolution image data. The method further includes performing a pharmacokinetic analysis to obtain data including at least one parameter that characterizes the tissue, providing a multi-parameter look-up table derived from a combination of two or more parameters, and providing a display including one parameter or a parametric image, where the parametric image is derived from the look-up table.

摘要翻译： 用于进行快速增强组织的组织参数计算的高分辨率药代动力学分析的方法使得医务人员能够准确地确定快速增强组织中的药代动力学参数。 该方法包括：当组织处于稳定状态时获得组织的掩模图像数据，当造影剂在组织中流动时获得组织的图像数据的时间序列，并且增加图像的时间序列的空间分辨率 使用掩模图像数据的数据来获得增加的空间分辨率图像数据的时间序列。 该方法还包括进行药代动力学分析以获得包括表征组织的至少一个参数的数据，提供从两个或多个参数的组合导出的多参数查找表，以及提供包括一个参数或参数的显示 图像，其中参数图像从查找表导出。

公开(公告)号：US20100128950A1

公开(公告)日：2010-05-27

申请号：US12579898

申请日：2009-10-15

申请人： Kevin Woods ,  Michael J. Collins ,  Senthil Periaswamy ,  Robert L. Van Uitert

发明人： Kevin Woods ,  Michael J. Collins ,  Senthil Periaswamy ,  Robert L. Van Uitert

IPC分类号： G06K9/00 ,  H05G1/60

CPC分类号： A61B6/5217 ,  A61B6/03 ,  A61B6/502 ,  G06K9/3233 ,  G06K2209/053 ,  G06T7/0012 ,  G06T2207/10072 ,  G06T2207/10124 ,  G06T2207/20104 ,  G06T2207/20108 ,  G06T2207/30068

摘要： Disclosed are methods, and associated systems comprising processors, input devices and output devices, of detecting regions of interest in a tomographic breast image. The methods may comprise: acquiring tomographic breast image data; deriving a plurality of synthetic sub-volumes from the tomographic breast image data; wherein each subvolume is defined by parallel planar top and bottom surfaces; wherein planar top and bottom surfaces of successive subvolumes are parallel to each other; and wherein a top planar surface of a sub-volume is offset from a top planar surface of a prior sub-volume, such that successive sub-volumes overlap; for each sub-volume, deriving a two-dimensional image; for each two-dimensional image, identifying regions of interest therein; deriving at least one region of interest of potential clinical interest from a plurality of identified regions of interest; and outputting information associated with at least one derived region of interest of potential clinical interest.

摘要翻译： 公开了包括处理器，输入设备和输出设备的方法和相关系统，其检测断层图像乳房图像中的感兴趣区域。 所述方法可以包括：获取断层摄影乳房图像数据; 从断层图像乳房图像数据中导出多个合成子体积; 其中每个子体积由平行的平面顶部和底部表面限定; 其中连续子体积的平面顶表面和底表面彼此平行; 并且其中子体积的顶部平坦表面偏离先前子体积的顶部平坦表面，使得连续的子体积重叠; 对于每个子体积，导出二维图像; 对于每个二维图像，识别其中感兴趣的区域; 从多个确定的感兴趣区域中产生潜在临床兴趣的至少一个感兴趣区域; 并输出与潜在临床感兴趣的至少一个感兴趣的衍生区域相关联的信息。

公开(公告)号：US07672496B2

公开(公告)日：2010-03-02

申请号：US11472175

申请日：2006-06-21

申请人： Michael J. Collins

发明人： Michael J. Collins

IPC分类号： G06K9/00

CPC分类号： G06K9/34 ,  G06K9/4638 ,  G06K2209/05

摘要： A decision rule is used that examines the computer-aided detected (CAD) regions of interest in a computed tomography (CT) slice pair taken from volumetric medical CT scan to determine whether the detected regions of interest are part of the same object is disclosed. Segmentation is performed after initially detecting a region of interest but before calculating features in order to refine the boundaries of the detected regions of interest. Segmentation occurs in the two-dimensional slices by segmenting the region of interest on each slice. Adjacent slices are examined to determine if adjacent objects are actually part of the same structure. If they are not, the objects are split apart. In this way, three-dimensional objects are formed from two-dimensional segmentations.

摘要翻译： 使用决定规则，其检查从体积医学CT扫描获取的计算机断层摄影（CT）切片对中的计算机辅助检测（CAD）区域，以确定检测到的感兴趣区域是否是同一对象的一部分。 在最初检测到感兴趣区域之后但在计算特征之前执行分割，以便细化检测到的感兴趣区域的边界。 通过在每个切片上分割感兴趣区域，在二维切片中发生分割。 检查相邻切片以确定相邻对象是否实际上是相同结构的一部分。 如果不是，物体就会分开。 以这种方式，三维物体由二维分割形成。

公开(公告)号：US10376230B2

公开(公告)日：2019-08-13

申请号：US15035743

申请日：2014-11-10

申请人： iCAD, Inc.

发明人： Jeffrey C. Wehnes ,  Arunkumar Gururajan ,  James Monaco ,  Ronald Larcom ,  James H. Pike

IPC分类号： G06T7/00 ,  A61B6/00 ,  G06T7/11

摘要： Breast density measurements are used to perform Breast Imaging Reporting and Data System (BI-RADS) classification during breast cancer screenings. The accuracy of breast density measurements can be improved by quantitatively processing digital mammographic images. For example, breast segmentation may be performed on a mammographic image to isolate the breast tissue from the background and pectoralis tissue, while a breast thickness adjustment may be performed to compensate for decreased tissue thickness near the skin line of the breast. In some instances, BI-RADS density categorization may consider the degree to which dense tissue is dispersed throughout the breast. A breast density dispersion parameter can also be obtained using quantitative techniques, thereby providing objective BI-RADS classifications that are less susceptible to human error.

公开(公告)号：US20140198965A1

公开(公告)日：2014-07-17

申请号：US14160496

申请日：2014-01-21

申请人： iCAD, Inc.

发明人： Kevin Woods ,  Michael J. Collins ,  Senthil Periaswamy ,  Robert Van Uitert

IPC分类号： G06T7/00 ,  A61B6/00

CPC分类号： A61B6/5217 ,  A61B6/03 ,  A61B6/502 ,  G06K9/3233 ,  G06K2209/053 ,  G06T7/0012 ,  G06T2207/10072 ,  G06T2207/10124 ,  G06T2207/20104 ,  G06T2207/20108 ,  G06T2207/30068

摘要： Disclosed are methods, and associated systems comprising processors, input devices and output devices, of detecting regions of interest in a tomographic breast image. The methods may comprise: acquiring tomographic breast image data; deriving a plurality of synthetic sub-volumes from the tomographic breast image data; wherein each subvolume is defined by parallel planar top and bottom surfaces; wherein planar top and bottom surfaces of successive subvolumes are parallel to each other; and wherein a top planar surface of a sub-volume is offset from a top planar surface of a prior sub-volume, such that successive sub-volumes overlap; for each sub-volume, deriving a two-dimensional image; for each two-dimensional image, identifying regions of interest therein; deriving at least one region of interest of potential clinical interest from a plurality of identified regions of interest; and outputting information associated with at least one derived region of interest of potential clinical interest.

摘要翻译： 公开了包括处理器，输入设备和输出设备的方法和相关系统，其检测断层图像乳房图像中的感兴趣区域。 所述方法可以包括：获取断层摄影乳房图像数据; 从断层图像乳房图像数据中导出多个合成子体积; 其中每个子体积由平行的平面顶部和底部表面限定; 其中连续子体积的平面顶表面和底表面彼此平行; 并且其中子体积的顶部平坦表面偏离先前子体积的顶部平坦表面，使得连续的子体积重叠; 对于每个子体积，导出二维图像; 对于每个二维图像，识别其中感兴趣的区域; 从多个确定的感兴趣区域中产生潜在临床兴趣的至少一个感兴趣区域; 并输出与潜在临床感兴趣的至少一个感兴趣的衍生区域相关联的信息。