公开(公告)号：US20170247396A1

公开(公告)日：2017-08-31

申请号：US15510168

申请日：2015-09-09

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Nicholas R. Wurtz ,  Andrew Quoc Viet ,  Scott A. Shaw ,  Benjamin P. Vokits ,  Ellen K. Kick ,  Meriah Neissel Valente ,  Andrew K. Dilger ,  Kumar Balashanmuga Pabbisetty ,  Sutjano Jusuf

IPC: C07D519/00 ,  C07D487/04 ,  C07D471/04

CPC classification number: C07D519/00 ,  A61K31/437 ,  A61K31/519 ,  C07D471/04 ,  C07D487/04

Abstract: The present invention provides compounds of Formula (I): wherein A and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.