摘要:
This invention provides for methods of sequencing and performing polymerase reactions using an improved generation of nucleic acid polymerases. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the processivity of the polymerase.
摘要:
The invention is directed to substituted 2-aminoacetamides represented by formula (II): and to pharmaceutically acceptable salts and prodrugs thereof, wherein the substituents are defined herein. The invention is also directed to the use of substituted 2-aminoacetamides in methods for the treatment of neuronal damage following global and focal ischemia, and for the treatment, prevention or amelioration of pain, anxiety, or manic depression, as anticonvulsants, as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
摘要:
This invention provides methods and kits for performing a quantitative amplification reaction. The method employs a polymerase enzyme and an enzyme having a 3′ to 5′ exonuclease activity that cleaves the 3′ oligonucleotide of the probe.
摘要:
A main board and a method for dynamically configuring PCIE ports thereof. The main board comprises a PCIE slot, a detecting circuit, an ROM, a chipset and a modifying circuit. The chipset comprises a Management Engine controller and several PCIE ports. The chipset has a Management Engine function or a similar function. The detecting circuit detects the PCIE slot to generate a current state parameter. The ROM stores a default configuration data. The modifying circuit coupled between the chipset and the ROM determines whether the default configuration data needs to be modified according to the current state parameter. When the default configuration data needs to be modified, the modifying circuit modifies the default configuration data according to the current state parameter, so that the Management Engine controller initially configures the PCIE ports according to the modified default configuration data. Thus, the dynamical configuration of the chipset PCIE ports is realized.
摘要:
A method and a device for maintaining a Long Term Evolution (LTE) base station are provided by the embodiments of the present invention. Depending on the LTE access network system and air interface characteristics, by making a few processing flow changes in such mode or method, a wireless communication link is established between a network maintenance device and a base station to implement the base station maintenance and data communication. Application of the technical solutions provided by the embodiments of the present invention can implement the base station maintenance and data communication by the wireless mode, reduce the cost of the network maintenance and prevent the destruction and influence of human factors on the operation and maintenance of the base station.
摘要:
The present invention provides a method and an apparatus for abstracting logical topology information of a Peer-to-Peer (P2P) network. The method includes: obtaining a set of Points of Presence (POPs) of peer clients in the P2P network; using a relevant algorithm of a routing protocol to calculate a best path between any two POPs in the set of POPs and a weight value of the best path; and collecting calculation results of the best path and the weight value that are obtained on each POP to obtain a set of abstract logical topology records of the P2P network. The embodiments of the present invention provide a universal and efficient method for abstracting logical topology information, which greatly reduces network topology information that needs to be transmitted, mitigates a risk of exposing lower-layer network topology information, and transmits the network topology information to a P2P application server securely and concisely.
摘要:
The present invention provides novel imidazolidinonyl aminopyrimidine compounds believed to have clinical use for treatment of cancer through inhibiting Plk1. wherein: R1 hydrogen, hydroxy, halo, methyl, C1-C2 alkoxy, amino, or methylamino; R2 is hydrogen, halo, or cyano; R3 is hydrogen or halo; R4 is hydrogen, halo, or methyl; provided that at least two of R1, R2, R3, and R4 are hydrogen; R5 is hydrogen, halo, or methyl; or a pharmaceutically acceptable salt thereof.
摘要:
A biodegradable, polyolefin-based material composition having incorporated therein thermoplastic starch particles is described. The material includes from about 5% to about 45% of a thermoplastic starch (TPS), from about 55% to about 95% of a polyolefin or mixtures of polyolefins, and from about 0.5% to about 8% of a compatibilizer, which has a non-polar backbone and a polar functional monomer or a block copolymer of both the non-polar block and a polar block. A method of forming a film and packaging assemblies made with the polymeric material are also described.