System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue
    23.
    发明授权
    System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue 有权
    使用单次细胞分割在连续染色的组织上进行复合生物标志物定量的系统和方法

    公开(公告)号:US08995740B2

    公开(公告)日:2015-03-31

    申请号:US13865036

    申请日:2013-04-17

    Abstract: Improved systems and methods for the analysis of digital images are provided. More particularly, the present disclosure provides for improved systems and methods for the analysis of digital images of biological tissue samples. Exemplary embodiments provide for: i) segmenting, ii) grouping, and iii) quantifying molecular protein profiles of individual cells in terms of sub cellular compartments (nuclei, membrane, and cytoplasm). The systems and methods of the present disclosure advantageously perform tissue segmentation at the sub-cellular level to facilitate analyzing, grouping and quantifying protein expression profiles of tissue in tissue sections globally and/or locally. Performing local-global tissue analysis and protein quantification advantageously enables correlation of spatial and molecular configuration of cells with molecular information of different types of cancer.

    Abstract translation: 提供了改进的数字图像分析系统和方法。 更具体地,本公开提供了用于分析生物组织样本的数字图像的改进的系统和方法。 示例性实施方案提供:i)分段,ii)分组,和iii)根据亚细胞区室(细胞核,膜和细胞质)量化各细胞的分子蛋白质谱。 本公开的系统和方法有利地在亚细胞水平进行组织分割,以便于全局和/或局部地分析,分组和定量组织部位中组织的蛋白质表达谱。 进行局部全局组织分析和蛋白质定量有利于使细胞的空间和分子构型与不同类型癌症的分子信息的相关性。

    MODELING OF PARALLEL SEISMIC TEXTURES
    24.
    发明申请
    MODELING OF PARALLEL SEISMIC TEXTURES 有权
    并行地震纹理建模

    公开(公告)号:US20140177390A1

    公开(公告)日:2014-06-26

    申请号:US13722755

    申请日:2012-12-20

    Inventor: Ali Can Erhan Bas

    Abstract: An approach for seismic data analysis is provided. In accordance with embodiments of this approach, parallel regions within a volume of seismic data are modeled. Residual regions within the volumetric data set are identified, where the residual regions comprise those regions not modeled as parallel regions. The residual regions or a graphic derived from the residual regions are displayed for review.

    Abstract translation: 提供了一种地震数据分析方法。 根据该方法的实施例,对地震数据量的平行区域进行建模。 识别体积数据集内的剩余区域,其中残余区域包括未被建模为平行区域的那些区域。 显示剩余区域或从残差区域导出的图形以供查看。

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