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公开(公告)号：US20080044887A1
公开(公告)日：2008-02-21
申请号：US11880836
申请日：2007-07-23
申请人： George Maltezos , Axel Scherer
发明人： George Maltezos , Axel Scherer
CPC分类号： C12N13/00 , B01J19/0093 , C02F1/30 , C02F3/327 , C02F3/348 , C10L1/026 , C12M21/02 , C12M23/06 , C12M23/16 , C12M31/04 , C12N1/12 , C12P3/00 , C12P7/6463 , C12P7/649 , Y02E50/13 , Y02W10/18 , Y02W10/37
摘要： Methods and devices of performing reactions for which presence of light is desirable are provided. Biological or chemical materials such as algae are put in a chamber shaped as a meandering fluid channel. The algae can be combined with biomass such as human or animal waste and then subject to light, such as natural light or light coming from a LED, to produce fuel. Production of fuel can be optimized by controlling the height-to-width ratio of the channels
摘要翻译： 提供了需要进行光的存在的反应的方法和装置。 将诸如藻类的生物或化学材料置于作为曲折流体通道形成的室中。 藻类可以与诸如人或动物废物的生物质结合，然后经受来自LED的光，例如自然光或光，以产生燃料。 可以通过控制通道的高宽比来优化燃料的生产
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公开(公告)号：US20080013092A1
公开(公告)日：2008-01-17
申请号：US11804112
申请日：2007-05-17
申请人： George Maltezos , John Lee , Axel Scherer , Emil Kartalov
发明人： George Maltezos , John Lee , Axel Scherer , Emil Kartalov
CPC分类号： G01N21/6456 , G01N21/6452 , Y10T137/2224
摘要： Microfluidic assay detectors and microfluidic assay detection methods are disclosed. A microfluidic chip is coupled to a light emitting device, emission filters and excitation filters. Excited fluorescent light is detected by a camera and a lens. The correspondent reading allows parallel detection of features such as antigens and biomarkers. A microfluidic filter and related methods are also disclosed. The filter can be used with on-chip fluid filtration such as whole blood filtration for microfluidic blood analysis. The filter is able to filter the necessary volume of fluid and in particular blood in an acceptable time frame.
摘要翻译： 公开了微流控测定检测器和微流控测定检测方法。 微流控芯片耦合到发光器件，发射滤光器和激发滤光器。 激发的荧光灯由相机和透镜检测。 通讯阅读允许并行检测抗原和生物标志物等特征。 还公开了微流体过滤器和相关方法。 过滤器可用于片上流体过滤，如全血过滤用于微流体血液分析。 过滤器能够在可接受的时间范围内过滤所需体积的流体，特别是血液。
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公开(公告)号：US20070104664A1
公开(公告)日：2007-05-10
申请号：US11552851
申请日：2006-10-25
申请人： George Maltezos , Axel Scherer
发明人： George Maltezos , Axel Scherer
CPC分类号： A61N5/0616 , A61F7/007 , A61F2007/0046 , A61N2005/0645 , A61N2005/0661
摘要： Aspects of the invention disclosed herein relate to devices that provide heat and/or ultraviolet light to fingernails or toenails that are afflicted by onychomycosis, as well as methods for treating onychomycosis by application of heat and/or ultraviolet light. The devices of the present invention may be used in connection with systemic and/or topical anti-fungal agents to treat onychomycosis.
摘要翻译： 本文公开的本发明的方面涉及向由甲真菌病所折磨的指甲或脚趾甲提供热和/或紫外光的装置以及通过施加热和/或紫外线治疗甲真菌病的方法。 本发明的装置可以与全身和/或局部抗真菌剂结合使用以治疗甲真菌病。
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公开(公告)号：US20070045880A1
公开(公告)日：2007-03-01
申请号：US11512053
申请日：2006-08-28
申请人： Aditya Rajagopal , Axel Scherer , George Maltezos
发明人： Aditya Rajagopal , Axel Scherer , George Maltezos
CPC分类号： H01L23/427 , F25B19/00 , F28C3/08 , F28D5/00 , F28D15/0233 , F28D2021/0052 , F28F2260/02 , H01L23/473 , H01L2924/0002 , H01L2924/00
摘要： Evaporative cooling is an effective and efficient method for rapidly removing heat from a system device. In accordance with the disclosure herein, a microfluidic Y-junction apparatus is provided which can produce low temperatures and can be integrated into microdevices.
摘要翻译： 蒸发冷却是快速从系统设备中去除热量的有效和有效的方法。 根据本文的公开内容，提供了可以产生低温并且可以集成到微器件中的微流控Y接合装置。
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公开(公告)号：US09212994B2
公开(公告)日：2015-12-15
申请号：US13348495
申请日：2012-01-11
申请人： George Maltezos , John Kim Lee , Axel Scherer , Emil Kartalov
发明人： George Maltezos , John Kim Lee , Axel Scherer , Emil Kartalov
CPC分类号： G01N21/6456 , G01N21/6452 , Y10T137/2224
摘要： A microfluidic filter is disclosed. The filter can be used with onchip fluid filtration such as whole blood filtration for microfluidic blood analysis. The filter is able to filter the necessary volume of fluid and in particular blood in an acceptable time frame.
摘要翻译： 公开了一种微流体过滤器。 过滤器可用于片上流体过滤，如全血过滤用于微流体血液分析。 过滤器能够在可接受的时间范围内过滤所需体积的流体，特别是血液。
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公开(公告)号：US09103786B2
公开(公告)日：2015-08-11
申请号：US13457199
申请日：2012-04-26
申请人： George Maltezos , Jeremy Witzens , Axel Scherer
发明人： George Maltezos , Jeremy Witzens , Axel Scherer
CPC分类号： G01N21/6428 , B01L3/50273 , B01L3/502738 , B01L2200/026 , B01L2200/027 , B01L2200/0605 , B01L2200/0689 , B01L2200/10 , B01L2200/141 , B01L2200/142 , B01L2200/143 , B01L2200/146 , B01L2200/148 , B01L2200/16 , B01L2300/042 , B01L2300/0654 , B01L2300/0819 , B01L2300/14 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0638 , B01L2400/0655 , B01L2400/0683 , B81C1/00119 , G01N21/03 , G01N21/0332 , G01N21/05 , G01N21/6456 , G01N2021/0321 , G01N2021/0325 , G01N2021/0346 , G01N2021/0364 , G01N2201/024 , Y10T137/0318 , Y10T137/0396 , Y10T137/1714 , Y10T137/2202 , Y10T137/8811
摘要： An apparatus for analysis of a sample and in particular of a biological sample. The apparatus contains a microfluidic chip with dies, adapted to be selectively activated or deactivated by presence of target molecules in the biological sample. The apparatus further contains a light source to emit light for illumination of the microfluidic chip and an optical filter to allow passage of the light from the dies once activated or deactivated by the presence of the target molecules. A method for pressurizing a microfluidic chip is also disclosed, where a chamber is provided, the chamber is connected with the microfluidic chip and pressure is applied to the chamber.
摘要翻译： 用于分析样品，特别是生物样品的装置。 该装置包含具有管芯的微流体芯片，适于通过生物样品中目标分子的存在而被选择性地活化或失活。 该装置还包含用于发射微流芯片照明的光源和滤光器，以允许通过靶分子的存在激活或去激活来自模具的光的通过。 还公开了一种用于对微流体芯片加压的方法，其中设置有腔室，腔室与微流体芯片连接，并且将压力施加到腔室。
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公开(公告)号：US08187541B2
公开(公告)日：2012-05-29
申请号：US11856722
申请日：2007-09-18
申请人： George Maltezos , Jeremy Witzens , Axel Scherer
发明人： George Maltezos , Jeremy Witzens , Axel Scherer
IPC分类号： G01N21/00 , G01N21/01 , G01N21/76 , G21K5/00 , C25B13/00 , G01N33/48 , F17D1/16 , F17D3/00 , G01J3/30 , G01B9/02
CPC分类号： G01N21/6428 , B01L3/50273 , B01L3/502738 , B01L2200/026 , B01L2200/027 , B01L2200/0605 , B01L2200/0689 , B01L2200/10 , B01L2200/141 , B01L2200/142 , B01L2200/143 , B01L2200/146 , B01L2200/148 , B01L2200/16 , B01L2300/042 , B01L2300/0654 , B01L2300/0819 , B01L2300/14 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0638 , B01L2400/0655 , B01L2400/0683 , B81C1/00119 , G01N21/03 , G01N21/0332 , G01N21/05 , G01N21/6456 , G01N2021/0321 , G01N2021/0325 , G01N2021/0346 , G01N2021/0364 , G01N2201/024 , Y10T137/0318 , Y10T137/0396 , Y10T137/1714 , Y10T137/2202 , Y10T137/8811
摘要： An apparatus for analysis of a sample and in particular of a biological sample. The apparatus contains a microfluidic chip with dies, adapted to be selectively activated or deactivated by presence of target molecules in the biological sample. The apparatus further contains a light source to emit light for illumination of the microfluidic chip and an optical filter to allow passage of the light from the dies once activated or deactivated by the presence of the target molecules. A method for pressurizing a microfluidic chip is also disclosed, where a chamber is provided, the chamber is connected with the microfluidic chip and pressure is applied to the chamber.
摘要翻译： 用于分析样品，特别是生物样品的装置。 该装置包含具有管芯的微流体芯片，适于通过生物样品中目标分子的存在而被选择性地活化或失活。 该装置还包含用于发射微流芯片照明的光源和滤光器，以允许通过靶分子的存在激活或去激活来自模具的光的通过。 还公开了一种用于对微流体芯片加压的方法，其中设置有腔室，腔室与微流体芯片连接，并且将压力施加到腔室。
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公开(公告)号：US08137626B2
公开(公告)日：2012-03-20
申请号：US11804112
申请日：2007-05-17
申请人： George Maltezos , John Kim Lee , Axel Scherer , Emil Kartalov
发明人： George Maltezos , John Kim Lee , Axel Scherer , Emil Kartalov
IPC分类号： G01N21/64
CPC分类号： G01N21/6456 , G01N21/6452 , Y10T137/2224
摘要： Microfluidic assay detectors and microfluidic assay detection methods are disclosed. A microfluidic chip is coupled to a light emitting device, emission filters and excitation filters. Excited fluorescent light is detected by a camera and a lens. The correspondent reading allows parallel detection of features such as antigens and biomarkers. A microfluidic filter and related methods are also disclosed. The filter can be used with on-chip fluid filtration such as whole blood filtration for microfluidic blood analysis. The filter is able to filter the necessary volume of fluid and in particular blood in an acceptable time frame.
摘要翻译： 公开了微流控测定检测器和微流控测定检测方法。 微流控芯片耦合到发光器件，发射滤光器和激发滤光器。 激发的荧光灯由相机和透镜检测。 通讯阅读允许并行检测抗原和生物标志物等特征。 还公开了微流体过滤器和相关方法。 过滤器可用于片上流体过滤，如全血过滤用于微流体血液分析。 过滤器能够在可接受的时间范围内过滤所需体积的流体，特别是血液。
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公开(公告)号：US07814928B2
公开(公告)日：2010-10-19
申请号：US11869718
申请日：2007-10-09
申请人： George Maltezos , Axel Scherer
发明人： George Maltezos , Axel Scherer
IPC分类号： F15B21/00
CPC分类号： G05D23/19 , Y10T137/6579 , Y10T137/6606 , Y10T137/8376
摘要： A microfluidic assembly comprising a replaceable microfluidic circuit and a thermal unit, the microfluidic circuit adapted to contact the thermal unit by contact between one or more membranes in the microfluidic circuit and the at least one temperature controlling element in the thermal unit to achieve temperature control of a substance or substances inside one or more fluidic compartments in the microfluidic circuit. A related method to control temperature and/or physical state of a substance in the fluidic compartments and related testing systems are also described.
摘要翻译： 一种包括可替换的微流体电路和热单元的微流体组件，所述微流体电路适于通过所述微流体回路中的一个或多个膜与所述热单元中的所述至少一个温度控制元件之间的接触来接触所述热单元，以实现温度控制 在微流体回路内的一个或多个流体室内的物质或物质。 还描述了用于控制流体隔间和相关测试系统中的物质的温度和/或物理状态的相关方法。
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公开(公告)号：US20100256551A1
公开(公告)日：2010-10-07
申请号：US12816972
申请日：2010-06-16
申请人： George Maltezos , Axel Scherer
发明人： George Maltezos , Axel Scherer
CPC分类号： A61N5/0616 , A61F7/007 , A61F2007/0046 , A61N2005/0645 , A61N2005/0661
摘要： Aspects of the invention disclosed herein relate to devices that provide heat and/or ultraviolet light to fingernails or toenails that are afflicted by onychomycosis, as well as methods for treating onychomycosis by application of heat and/or ultraviolet light. The devices of the present invention may be used in connection with systemic and/or topical anti-fungal agents to treat onychomycosis.
摘要翻译： 本文公开的本发明的方面涉及向由甲真菌病所折磨的指甲或脚趾甲提供热和/或紫外光的装置以及通过施加热和/或紫外线治疗甲真菌病的方法。 本发明的装置可以与全身和/或局部抗真菌剂结合使用以治疗甲真菌病。
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