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公开(公告)号:US20130116173A1
公开(公告)日:2013-05-09
申请号:US13728110
申请日:2012-12-27
Inventor: Richard D. DiMARCHI , Brian P. WARD
IPC: C07K14/605
CPC classification number: C07K14/605 , A61K38/00
Abstract: Provided herein are glucagon analogs which exhibit potent activity at the GIP receptor, and, as such are contemplated for use in treating diabetes and obesity. In exemplary embodiments, the glucagon analog of the present disclosures exhibit an EC50 at the GIP receptor which is within the nanomolar or picomolar range.