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公开(公告)号：US08107158B2
公开(公告)日：2012-01-31
申请号：US12853751
申请日：2010-08-10
申请人： Kenji Yamazaki , Nobuyuki Doguchi , Shunji Takei , Sakae Takehana
发明人： Kenji Yamazaki , Nobuyuki Doguchi , Shunji Takei , Sakae Takehana
IPC分类号： G02B26/00
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/0005 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B5/0075 , A61B5/0084
摘要： A fluorescent imaging device includes an irradiation section that irradiates an object to be examined with excitation light and reference light, an image pickup section that picks up a fluorescence image based on the excitation light and a reflected light image based on the reference light, a comparison section that compares relative intensity between the fluorescent image generated from the fluorescence image and the reflected light image generated from the reflected light image, and a selection section that selectively outputs one of the reflected light image and the fluorescent image based on the comparison result.
摘要翻译： 荧光成像装置包括：用激发光和参照光照射待检查对象的照射部，基于激发光拍摄荧光图像的摄像部和基于参照光的反射光图像;比较 比较从荧光图像生成的荧光图像与从反射光图像生成的反射光图像之间的相对强度的比较部分，以及基于比较结果选择性地输出反射光图像和荧光图像之一的选择部分。
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公开(公告)号：US07889228B2
公开(公告)日：2011-02-15
申请号：US11497742
申请日：2006-08-02
CPC分类号： H04N5/361 , A61B1/00006 , A61B1/00009 , A61B1/051 , G02B23/2476 , H01L27/148 , H04N5/367 , H04N5/372 , H04N5/37213 , H04N2005/2255
摘要： An endoscope includes a solid image-pickup device having an image area and an optical black area for performing photoelectric conversion and including a function of varying an amplification ratio, and a first signal clamp circuit clamps the analog output signal that is outputted from the solid image-pickup device to adjust into an input range of the analog signal processing circuit with an analog reference signal which is unaffected by a defective pixel in the optical black area. The clamped signal is processed to extract signal components which are photoelectrically converted by the analog signal processing circuit by the image area. The output signal from the analog signal processing circuit clamps the signal in the optical black area by using output signals of at least the number of pixels larger than the number of pixels in a horizontal direction in the optical black area by the second signal clamp circuit.
摘要翻译： 内窥镜包括具有用于进行光电转换并具有变化放大率的功能的图像区域和光学黑色区域的固体摄像装置，并且第一信号钳位电路钳位从实心图像输出的模拟输出信号 以使用不受光学黑色区域中的缺陷像素影响的模拟参考信号来调整到模拟信号处理电路的输入范围。 处理钳位信号以提取由模拟信号处理电路通过图像区域光电转换的信号分量。 来自模拟信号处理电路的输出信号通过使用比第二信号钳位电路在光学黑色区域中的水平方向上的像素数量的至少大的像素的数量的输出信号来将光信号中的信号钳位在光学黑色区域中。
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公开(公告)号：US20070002134A1
公开(公告)日：2007-01-04
申请号：US11497742
申请日：2006-08-02
CPC分类号： H04N5/361 , A61B1/00006 , A61B1/00009 , A61B1/051 , G02B23/2476 , H01L27/148 , H04N5/367 , H04N5/372 , H04N5/37213 , H04N2005/2255
摘要： An endoscope includes a solid image-pickup device having an image area and an optical black area for performing photoelectric conversion and including a function of varying an amplification ratio, and a first signal clamp circuit clamps the analog output signal that is outputted from the solid image-pickup device to adjust into an input range of the analog signal processing circuit with an analog reference signal which is unaffected by a defective pixel in the optical black area. The clamped signal is processed to extract signal components which are photoelectrically converted by the analog signal processing circuit by the image area. The output signal from the analog signal processing circuit clamps the signal in the optical black area by using output signals of at least the number of pixels larger than the number of pixels in a horizontal direction in the optical black area by the second signal clamp circuit.
摘要翻译： 内窥镜包括具有用于进行光电转换并具有变化放大率的功能的图像区域和光学黑色区域的固体摄像装置，并且第一信号钳位电路钳位从实心图像输出的模拟输出信号 以使用不受光学黑色区域中的缺陷像素影响的模拟参考信号来调整到模拟信号处理电路的输入范围。 处理钳位信号以提取由模拟信号处理电路通过图像区域光电转换的信号分量。 来自模拟信号处理电路的输出信号通过使用比第二信号钳位电路在光学黑色区域中的水平方向上的像素数量的至少大的像素的数量的输出信号来将光信号中的信号钳位在光学黑色区域中。
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公开(公告)号：US08868160B2
公开(公告)日：2014-10-21
申请号：US13495059
申请日：2012-06-13
申请人： Kei Kubo , Nobuyuki Doguchi
发明人： Kei Kubo , Nobuyuki Doguchi
CPC分类号： A61B1/043 , A61B1/00006 , A61B1/041 , A61B1/0661 , G06F19/00
摘要： A medical apparatus includes: a storing section in which information concerning a drug kinetics in a living body is stored in advance for each of plural kinds of fluorescent drugs; a processing section that acquires information concerning diagnosis start timing corresponding to a desired fluorescent drug based on information stored in the storing section, information concerning a target region to which the desired fluorescent drug is administered, information concerning a method of administering the desired fluorescent drug to the target region, and information indicating start of the administration of the desired fluorescent drug; and a light source control section that controls radiation of excitation light for exciting the desired fluorescent drug to a stop state until the diagnosis start timing is reached and controls, at and after the diagnosis start timing, the radiation of the excitation light to a state in which the excitation light can be radiated.
摘要翻译： 一种医疗装置，包括：存储部，其中预先为多种荧光药物中的每一种储存关于生物体中的药物动力学的信息; 根据存储在存储部中的信息获取与期望的荧光药物相对应的诊断开始时刻的信息的处理部，关于所需要的荧光药物的目标区域的信息，与所需荧光药物的给药方法有关的信息 目标区域和指示所需荧光药物的给药开始的信息; 以及光源控制部，其控制用于将期望的荧光药物激发的激发光的放射线达到停止状态，直到达到诊断开始时刻为止，并且在诊断开始时刻之后及之后将激发光的照射控制到 激发光可以被辐射。
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公开(公告)号：US08202214B2
公开(公告)日：2012-06-19
申请号：US11917436
申请日：2006-04-26
CPC分类号： A61B1/00096 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/0676 , A61B1/0684
摘要： There is provided an endoscope capable of observing cells at a desired position existing in the depth direction with a simple structure as compared to the conventional configuration. The endoscope includes an insert unit to be inserted into a biological body, a low-scaling observation system for observing an observation position in a biological body with a low scaling, and a high-scaling observation system for observing a target position of the aforementioned observation position as a local position with a high scaling. The high-scaling observation system includes a plurality of illumination units for applying illumination light for high-scaling observation of the target position. The illumination units are arranged at predetermined positions of the end face of the insert unit.
摘要翻译： 与常规结构相比，提供了能够以简单的结构在深度方向上存在的期望位置观察细胞的内窥镜。 内窥镜包括插入生物体的插入单元，用于以低比例观察生物体中的观察位置的低比例观察系统和用于观察上述观察的目标位置的高比例观察系统 作为具有高比例缩放的本地位置的位置。 高比例观察系统包括用于施加照明光的多个照明单元，用于高标度地观察目标位置。 照明单元布置在插入单元的端面的预定位置。
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公开(公告)号：US20090088601A1
公开(公告)日：2009-04-02
申请号：US12277898
申请日：2008-11-25
申请人： Nobuyuki Doguchi , Hironobu Ichimura , Hideyasu Takato , Azusa Noguchi , Kazuhiro Gono , Kiyoshi Miyake
发明人： Nobuyuki Doguchi , Hironobu Ichimura , Hideyasu Takato , Azusa Noguchi , Kazuhiro Gono , Kiyoshi Miyake
IPC分类号： A61B1/00
CPC分类号： A61B1/0125 , A61B1/015 , A61B2090/3912 , A61B2090/395 , G02B23/2423
摘要： An endoscope has an insertion portion, a contact portion, an observation portion and a marking portion. The insertion portion can be inserted into a body cavity. The contact portion is provided at a distal end portion of the insertion portion. The contact portion provided at the distal end portion can be in contact with a subject. The observation portion is provided at the contact portion. The marking portion is provided at the contact portion. The marking portion applies a marker to the subject with which the contact portion is in contact.
摘要翻译： 内窥镜具有插入部，接触部，观察部和标记部。 插入部分可插入体腔。 接触部设置在插入部的前端部。 设置在前端部的接触部可以与被检体接触。 观察部设置在接触部。 标记部分设置在接触部分处。 标记部分将标记施加到与接触部分接触的对象。
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公开(公告)号：US20090082626A1
公开(公告)日：2009-03-26
申请号：US12323065
申请日：2008-11-25
申请人： Hironobu Ichimura , Hideyasu Takato , Azusa Noguchi , Kiyoshi Miyake , Nobuyuki Doguchi , Kazuhiro Gono
发明人： Hironobu Ichimura , Hideyasu Takato , Azusa Noguchi , Kiyoshi Miyake , Nobuyuki Doguchi , Kazuhiro Gono
CPC分类号： G02B23/2438 , A61B1/00082 , A61B1/0125 , A61B5/6886 , G02B23/2446 , G02B23/2484
摘要： An endoscope has an insertion portion, an abutment portion, an increasing device and an observation portion. The insertion portion is an insertion portion which can be inserted into a subject. The abutment portion is provided at a distal end portion of the insertion portion. The abutment portion provided at the distal end portion can contact with the subject. The increasing device increases the abutment area of the abutment portion. The observation portion performs observation of the subject on the abutment portion provided at the distal end portion and having been increased by the increasing device, or performs observation of the subject spaced by a predetermined distance by the increased abutment portion.
摘要翻译： 内窥镜具有插入部，抵接部，增大装置和观察部。 插入部是能够插入到被检体内的插入部。 该抵接部设置在插入部的前端部。 设置在前端部的抵接部可以与被检体接触。 增加的装置增加邻接部分的邻接面积。 观察部在被设置在前端部的抵接部上进行被检体的观察，并且通过增大装置增加，或者通过增大的邻接部进行间隔了规定距离的被检体。
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公开(公告)号：US08542272B2
公开(公告)日：2013-09-24
申请号：US12629394
申请日：2009-12-02
申请人： Shunji Takei , Nobuyuki Doguchi , Kenji Yamazaki
发明人： Shunji Takei , Nobuyuki Doguchi , Kenji Yamazaki
IPC分类号： A62B1/04
CPC分类号： A61B1/05 , A61B1/00096 , A61B1/043 , A61B1/0638 , A61B1/0646
摘要： An image generating apparatus according to the present invention includes: a first light source unit that emits light in a first wavelength band to a subject; a second light source unit that emits light in a second wavelength band, which is a part of the first wavelength band, to the subject; an image pickup unit that picks up an image of the subject and outputs the image as an image pickup signal; a light cut filter unit that cuts light in the second wavelength band reflected from the subject; and a complementary processing unit that applies complementary processing to a component equivalent to the second wavelength band cut by the light cut filter unit in the image of the subject picked up by the image pickup unit in a state in which the subject is illuminated by the light in the first wavelength band.
摘要翻译： 根据本发明的图像产生装置包括：第一光源单元，其将第一波长带的光发射到被摄体; 第二光源单元，其将作为第一波长带的一部分的第二波长带的光发射到被摄体; 拾取单元，其拾取被摄体的图像并输出图像作为摄像信号; 切割过滤器单元，其切断从被检体反射的第二波长带的光; 以及互补处理单元，其在被所述被摄体被所述光照射的状态下，对由所述摄像单元拾取的所述被摄体的图像中的由所述遮光滤光器单元切割的所述第二波长带相当的成分进行补充处理 在第一波长带。
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公开(公告)号：US20100137682A1
公开(公告)日：2010-06-03
申请号：US11917436
申请日：2006-04-26
CPC分类号： A61B1/00096 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61B1/0676 , A61B1/0684
摘要： There is provided an endoscope capable of observing cells at a desired position existing in the depth direction with a simple structure as compared to the conventional configuration. The endoscope includes an insert unit to be inserted into a biological body, a low-scaling observation system for observing an observation position in a biological body with a low scaling, and a high-scaling observation system for observing a target position of the aforementioned observation position as a local position with a high scaling. The high-scaling observation system includes a plurality of illumination units for applying illumination light for high-scaling observation of the target position. The illumination units are arranged at predetermined positions of the end face of the insert unit.
摘要翻译： 与常规结构相比，提供了能够以简单的结构在深度方向上存在的期望位置观察细胞的内窥镜。 内窥镜包括插入生物体的插入单元，用于以低比例观察生物体中的观察位置的低比例观察系统和用于观察上述观察的目标位置的高比例观察系统 作为具有高比例缩放的本地位置的位置。 高比例观察系统包括用于施加照明光的多个照明单元，用于高标度地观察目标位置。 照明单元布置在插入单元的端面的预定位置。
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