公开(公告)号：US07653173B2

公开(公告)日：2010-01-26

申请号：US11906142

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to deriving at least one first X-ray fluorescence visualization, image, or provided information substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of directing an at least one first applied high energy photon and/or particle having an at least one first input energy towards the at least some matter of the at least the portion of the at least one individual. The aspect comprises deriving at least one second X-ray fluorescence visualization, image, or provided information substantially within the at least some matter of the at least the portion of the at least one individual at least partially as a result of directing an at least one second applied high energy photon and/or particle having an at least one second input energy toward the at least some matter of the at least the portion of the at least one individual. The aspect comprises deriving an at least one combined X-ray fluorescence visualization, combined image, or combined provided information at least partially by combining the at least one first X-ray fluorescence visualization, image, or provided information with the at least one second X-ray fluorescence visualization, image, or provided information.

摘要翻译： 一方面涉及至少部分地至少部分地导出至少一个第一X射线荧光可视化，图像或提供的信息，所述至少一个第一X射线荧光可视化，图像或提供的信息基本上在至少一个个体的至少一部分的至少一部分内， 首先将至少一个第一输入能量的高能光子和/或粒子应用于至少一个个体的至少一部分的至少一些物质。 该方面包括至少部分地至少部分地导出至少一个第二X射线荧光可视化，图像或提供的信息，所述至少一个第二X射线荧光可视化，图像或提供的信息基本上在所述至少一个个体的该至少一部分的至少一些事物内，作为指导至少一个 第二施加的高能量光子和/或具有至少一个第二输入能量的颗粒朝向至少一个个体的至少一部分的至少一些物质。 该方面包括至少部分地通过将至少一个第一X射线荧光可视化，图像或提供的信息与至少一个第二X射线荧光可视化，组合图像或组合提供的信息， 荧光可视化，图像或提供的信息。

公开(公告)号：US08285073B2

公开(公告)日：2012-10-09

申请号：US13199546

申请日：2011-08-31

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G06K9/40 ,  G06K9/00

CPC分类号： G06T5/006 ,  G06T2207/30012

摘要： Certain aspects can relate to responsive to the at least some input compensating information, imaging the at least the portion of the individual in a manner to limit at least some distorting effects of the at least the portion of the at least one distorting feature associated with the at least the portion of the individual at least partially by modifying a non-optical electromagnetic output from an imaging modality as applied to the at least the portion of the at least one distorting feature associated with the at least the portion of the individual. Certain aspects can relate to creating at least one conformal absence of a non-optical electromagnetic output to limit distortion to an imaging of an at least a portion of an individual resulting at least partially from at least one distorting feature associated with the at least the portion of the individual.

摘要翻译： 某些方面可以涉及响应于至少一些输入补偿信息，以至少限制与至少一个失真特征相关联的至少一个失真特征的至少一部分的至少一些失真效应的方式成像该个体的至少一部分 所述个体的至少一部分至少部分地通过当应用于与所述个体的至少一部分相关联的所述至少一个失真特征的所述至少一部分时，从成像模态修改非光学电磁输出。 某些方面可以涉及产生非光学电磁输出的至少一个共形缺失，以将失真限制到个体的至少一部分的成像，至少部分地由至少一个与至少部分相关联的变形特征 的个人。

公开(公告)号：US08041145B2

公开(公告)日：2011-10-18

申请号：US11601581

申请日：2006-11-17

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G06K9/40 ,  G06K9/00

CPC分类号： G06T5/006 ,  G06T2207/30012

摘要： Certain aspects can relate to responsive to the at least some input compensating information, imaging the at least the portion of the individual in a manner to limit at least some distorting effects of the at least the portion of the at least one distorting feature associated with the at least the portion of the individual at least partially by modifying a non-optical electromagnetic output from an imaging modality as applied to the at least the portion of the at least one distorting feature associated with the at least the portion of the individual. Certain aspects can relate to creating at least one conformal absence of a non-optical electromagnetic output to limit distortion to an imaging of an at least a portion of an individual resulting at least partially from at least one distorting feature associated with the at least the portion of the individual.

摘要翻译： 某些方面可以涉及响应于至少一些输入补偿信息，以至少限制与至少一个失真特征相关联的至少一个失真特征的至少一部分的至少一些失真效应的方式成像该个体的至少一部分 所述个体的至少一部分至少部分地通过当应用于与所述个体的至少一部分相关联的所述至少一个失真特征的所述至少一部分时，从成像模态修改非光学电磁输出。 某些方面可以涉及产生非光学电磁输出的至少一个共形缺失，以将失真限制到个体的至少一部分的成像，至少部分地由至少一个与至少部分相关联的变形特征 的个人。

公开(公告)号：US08041006B2

公开(公告)日：2011-10-18

申请号：US11888891

申请日：2007-08-01

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： G01T1/161

摘要： One aspect relates to visualizing, imaging, or providing information at least partially through at least some matter of an at least a portion of an individual, based at least in part on Compton scattering to at least partially form scattered X-rays, the Compton scattering occurring primarily in the at least some matter of the at least the portion of the individual, wherein the visualizing, imaging, or providing information is at least partially performed by converting the scattered X-rays into an at least one scintillated viewable and/or visible light that is detectable by a user. Another aspect relates to Compton scattered X-ray based visualizing, imaging, or providing information of an at least some matter of an at least a portion of an at least one individual to allow the at least one individual and/or an untrained assistant to at least partially visualize, image, or provide information into the at least some matter of the at least the portion of the individual based at least partially on Compton scattered X-rays.

摘要翻译： 一个方面涉及至少部分地基于康普顿散射来至少部分地通过个体的至少一部分的至少一部分来可视化，成像或提供信息，以至少部分地形成散射X射线，康普顿散射 主要发生在个体的至少一部分的至少一些物质中，其中可视化，成像或提供信息至少部分地通过将散射的X射线转换成至少一个闪烁的可见和/或可见的 可由用户检测的光。 另一方面涉及康普顿分散的基于X射线的可视化，成像或提供至少一个至少一个个体的至少一部分的信息，以允许至少一个个体和/或未经训练的助理在 至少部分地基于康普顿散射的X射线部分地可视化，图像或将信息提供给个体至少部分的至少一部分。

公开(公告)号：US08000438B2

公开(公告)日：2011-08-16

申请号：US11906169

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： Certain embodiments of one aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the least the portion of the at least one individual. The aspect can include X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual at least partially in response to the inducing at least one induced X-ray fluorescing photon within the at least some matter of the least the portion of the at least one individual. Certain embodiments of the aspect can include providing a substantial real time tool-based operation to the at least some matter of the least the portion of the at least one individual at least partially relying on the X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual.

摘要翻译： 一个方面的某些实施方案涉及在至少一些输入能量的至少一些输入能量的至少一个的至少一部分内的至少一些物质内诱导至少一个诱导的X射线荧光光子，所述至少一些输入能量被施加到所述至少一些 至少一个人的至少一部分的事物。 所述方面可以包括至少部分响应于诱导至少一个诱导的X射线荧光光子的至少一个个体的至少一部分内的至少一些物质内的X射线荧光可视化，成像或信息提供 所述至少一个个体的至少一部分的至少一部分。 该方面的某些实施例可以包括至少部分地依赖于X射线荧光可视化，成像或提供信息的至少一个个体的至少一部分的至少一些物质提供基本实时的基于工具的操作 在至少一个个体的至少一部分内的至少一些事物内。

公开(公告)号：US07742567B2

公开(公告)日：2010-06-22

申请号：US11786759

申请日：2007-04-11

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： A61B6/483 ,  A61B6/12 ,  A61B6/145 ,  A61B6/482 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B6/548 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

摘要： One aspect relates to locating an at least one scattering event at least partially within an at least some matter of an at least a portion of an individual at least partially by directing an at least one pulse-type applied X-ray at the at least some matter of the at least the portion of the individual to create an at least one corresponding pulse-type Compton scattered X-ray, wherein the locating the at least one scattering event is based at least in part on an at least one time of flight computation derived at least in part from a combination of an at least one applied duration and an at least one scattered duration, wherein the at least one applied duration corresponds to a time for the at least one pulse-type applied X-ray to reach the at least one scattering event within the at least some matter of the at least the portion of the individual, and further wherein the at least one scattered duration corresponds to a time for the at least one corresponding pulse-type Compton scattered X-ray to thereupon travel from the at least one scattering event within the at least some matter of the at least the portion of the individual to be detected.

摘要翻译： 一个方面涉及至少部分地至少部分地至少部分地位于个体的至少一部分内的至少一个散射事件，至少部分地通过将至少一个脉冲型施加的X射线引导到至少一些 该个体的至少一部分的物质以产生至少一个对应的脉冲型康普顿散射X射线，其中定位该至少一个散射事件至少部分地基于至少一次飞行时间计算 至少部分地来自至少一个施加持续时间和至少一个散射持续时间的组合，其中所述至少一个施加的持续时间对应于所述至少一个脉冲型施加的X射线到达所述时间的时间 在所述个体的至少一部分的至少一些物质内的至少一个散射事件，并且其中所述至少一个散射持续时间对应于所述至少一个对应的脉冲型康普顿散射的时间 X射线随后从至少一个待检测个体的该部分的至少一些物质内的至少一个散射事件行进。

公开(公告)号：US07738627B2

公开(公告)日：2010-06-15

申请号：US11906156

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to determining a location of an at least one X-ray fluorescing event occurring within an at least some matter of at least a portion of an individual, wherein the determining the location of the at least one X-ray fluorescing event is based at least in part on determining a relative angle at which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a relative position from which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a detected location of an at least one induced fluorescing X-ray photon fluoresced during the at least one X-ray fluorescing event, and a received angle at which the at least one induced fluorescing X-ray photon is received.

摘要翻译： 一个方面涉及确定发生在个体至少一部分的至少一部分内的至少一个X射线荧光事件的位置，其中确定至少一个X射线发荧光事件的位置是基于 至少部分地基于确定至少一个所施加的高能量光子和/或颗粒被施加到所述至少所述个体的所述部分中的所述至少一些物质的相对角度，相对位置至少一个 一个应用的高能量光子和/或粒子被施加到个体的至少一部分的至少一些物质，在至少一个X射线照射期间发现荧光的至少一个感应的荧光X射线光子的检测位置， 射线荧光事件和接收至少一个感应的荧光X射线光子的接收角度。

公开(公告)号：US07734012B2

公开(公告)日：2010-06-08

申请号：US11786758

申请日：2007-04-11

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： A61B6/483 ,  A61B6/12 ,  A61B6/145 ,  A61B6/482 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B6/548 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

摘要： One aspect relates to capturing one or more tomographic-type Compton scattering based visualizations, images, or provided information of an at least some matter of at least a portion of an individual based at least partially on Compton scattering of an at least one X-ray being applied to the at least some matter of the at least the portion of the individual. Another aspect relates to deriving an at least one material characteristic distribution function that substantially fits at least some data obtained at least partially by scattering of an at least one applied X-ray within at least some matter of at least a portion of an individual to form at least one Compton scattered X-ray.

摘要翻译： 一个方面涉及至少部分地至少部分地基于至少一个X射线的康普顿散射捕获一个或多个层析摄影类型的基于康普顿散射的可视化，图像或至少部分个体的提供的信息 被应用于个人的至少一部分的至少一些事物。 另一方面涉及导出至少一种材料特征分布函数，其基本上适合于至少部分地通过在个体的至少一部分的至少一部分内的至少一部分内散射至少一个施加的X射线而获得的至少一些数据，以形成 至少有一个康普顿分散的X光片。

公开(公告)号：US08215311B2

公开(公告)日：2012-07-10

申请号：US12800188

申请日：2010-05-11

申请人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  John D. Rinaldo, Jr. ,  Michael A. Smith ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  John D. Rinaldo, Jr. ,  Michael A. Smith ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： A61G15/00 ,  A47B71/00 ,  A47B7/00

CPC分类号： A61F5/05 ,  A61G5/1043 ,  A61G7/05707 ,  A61G7/0573 ,  A61G13/12 ,  A61G2203/34

摘要： One aspect relates to reducing a pressure differential across one or more supporting surfaces of a body surface of an individual at least partially by displacing at least one displaceable contouring unit to at least partially conform to one or more contours of the body surface of the individual. Certain aspects can relate to stabilizing at least the one or more supporting surfaces of the body surface of the individual at least partially with at least one of the at least one displaceable contouring unit Other aspects can relate to relatively displacing at least one displaceable contouring unit with respect to a medical device portion based at least in part on a contour of an individual to support at least a portion of the individual while limiting pressure applied to the individual.

摘要翻译： 一个方面涉及通过使至少一个可移位的轮廓单元至少部分地符合个体的身体表面的一个或多个轮廓来至少部分地减小穿过个体的身体表面的一个或多个支撑表面的压差。 至少部分地至少部分地使至少一个可移位的轮廓单元稳定至少一个或多个支撑表面的某些方面可以涉及至少一个可移动轮廓加工单元中的至少一个。其它方面可以涉及相对移位至少一个可移位的轮廓单元， 至少部分地基于个体的轮廓来相对于医疗装置部分，以支持个体的至少一部分，同时限制施加到个体的压力。

公开(公告)号：US07873234B2

公开(公告)日：2011-01-18

申请号：US11598214

申请日：2006-11-09

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G06K9/40 ,  G06K9/00

CPC分类号： G01R33/565

摘要： Certain aspects can relate to obtaining at least some input compensating information at least partially based on the distortion characterizing imaging information that when applied to an imaging modality used to obtain the at least one image information can limit distortions to the at least the portion of the at least one image information resulting from at least a portion of at least one distorting feature, wherein the at least some input compensating information is characterized based at least in part on the at least one relative orientation of the at least the portion of the at least one distorting feature relative to the at least one image information.

摘要翻译： 至少部分地基于失真表征成像信息来获得至少一些输入补偿信息的某些方面可以涉及当应用于用于获得所述至少一个图像信息的成像模态时可以限制到at的至少一部分的失真 至少一个图像信息由至少一个失真特征的至少一部分产生，其中所述至少一些输入补偿信息至少部分地基于至少一个至少一个失真特征的至少一个部分的至少一个相对取向来表征 相对于至少一个图像信息的扭曲特征。