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公开(公告)号：US20120043227A1
公开(公告)日：2012-02-23
申请号：US13317662
申请日：2011-10-25
IPC分类号： G01N27/327
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
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公开(公告)号：US20110132776A1
公开(公告)日：2011-06-09
申请号：US12931296
申请日：2011-01-28
IPC分类号： G01N27/327 , G01N33/50
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
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公开(公告)号：US20100252454A1
公开(公告)日：2010-10-07
申请号：US12802608
申请日：2010-06-10
IPC分类号： G01N27/403
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
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公开(公告)号：US20130020208A1
公开(公告)日：2013-01-24
申请号：US13609305
申请日：2012-09-11
IPC分类号： G01N27/327
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。
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公开(公告)号：US20100320097A1
公开(公告)日：2010-12-23
申请号：US12803253
申请日：2010-06-22
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。
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26.发明申请Biosensor, measuring instrument for biosensor, and method of quantifying substrate 审中-公开生物传感器，生物传感器的测量仪器和定量底物的方法公开(公告)号：US20080110754A1
公开(公告)日：2008-05-15
申请号：US11800273
申请日：2007-05-03
IPC分类号： G01N27/26
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。
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公开(公告)号：US20060175206A1
公开(公告)日：2006-08-10
申请号：US11378682
申请日：2006-03-17
IPC分类号： C12Q1/00 , G01N33/487 , G01F1/64
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
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公开(公告)号：US5512159A
公开(公告)日：1996-04-30
申请号：US293131
申请日：1994-08-19
申请人： Toshihiko Yoshioka , Mariko Kawaguri , Shiro Nankai , Haruhiro Tsutsumi , Hideyuki Baba , Yoshinobu Tokuno , Shoji Miyazaki
发明人： Toshihiko Yoshioka , Mariko Kawaguri , Shiro Nankai , Haruhiro Tsutsumi , Hideyuki Baba , Yoshinobu Tokuno , Shoji Miyazaki
IPC分类号： G01N27/28 , C12M1/34 , C12M1/40 , C12Q1/00 , C12Q1/54 , G01N27/327 , G01N33/483
CPC分类号： C12Q1/001
摘要： A biosensor of the present invention is provided with an insulating base plate, an electrode system mainly consisting of a working electrode and a counter electrode formed on the insulating base plate, and a reaction layer on the electrode system. The counter electrode is partially a circular arc. A manufacturing method of the biosensor of the present invention is comprised of a step to form a base by arranging leads, an electrode system, and an insulating layer on an insulating base plate, and a step to form a reaction layer mainly composed of an enzyme on the electrode system. Since the counter electrode is partially in the shape of a circular arc, the reaction layer is easily formed and prevented from delaminating, whereby the measuring accuracy, preservative properties and reliability of the biosensor are improved. The present invention enables highly efficient biosensors to be mass produced at low cost.
摘要翻译： 本发明的生物传感器设置有绝缘基板，主要由在绝缘基板上形成的工作电极和对电极组成的电极系统和电极系统上的反应层。 对电极部分是圆弧。 本发明的生物传感器的制造方法包括通过在绝缘基板上排列引线，电极系统和绝缘层形成基底的步骤，以及形成主要由酶组成的反应层的步骤 在电极系统上。 由于对电极部分为圆弧形状，反应层易于形成并防止分层，从而提高了生物传感器的测量精度，防腐性能和可靠性。 本发明能够以低成本批量生产高效生物传感器。
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29.发明授权Biosensor, measuring instrument for biosensor, and method of quantifying substrate 有权生物传感器，生物传感器的测量仪器和定量底物的方法公开(公告)号：US07850839B2
公开(公告)日：2010-12-14
申请号：US11378944
申请日：2006-03-16
IPC分类号： G01N27/327
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。
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30.发明授权Biosensor, measuring instrument for biosensor, and method of quantifying substrate 有权生物传感器，生物传感器的测量仪器和定量底物的方法公开(公告)号：US07232510B2
公开(公告)日：2007-06-19
申请号：US10182236
申请日：2001-11-30
IPC分类号： G01N27/327
CPC分类号： G01N27/327 , A61B5/1486 , A61B2562/0295 , C12Q1/001 , C12Q1/005 , C12Q1/006 , G01N27/26 , G01N27/3272 , G01N27/3274 , G01N33/48771 , G01N33/5438
摘要： A biosensor, a measuring instrument for biosensor, and a method of quantifying a substrate contained in specimen liquid to reduce a measurement error by the biosensor; a biosensor, comprising at least a pair of electrodes formed on an insulation substrate; a measuring instrument, comprising a supporting part for detachably supporting the biosensor, a plurality of connection terminals electrically connected to the electrodes, and a drive power supply for applying a voltage to the electrodes through the connection terminals; wherein the biosensor is inserted into the measuring instrument, either one of the electrodes of the biosensor is connected to first and second connection terminals fined to the measuring instrument only when the biosensor is inserted into the support part of the measuring instrument in a specified direction and has an electrode structure to allow the first connection terminal to conduct with the second connection terminal when a voltage is applied by the drive power supply.
摘要翻译： 生物传感器，生物传感器用测定装置以及检测用液体中含有的基板的量化方法，以减少生物传感器的测定误差。 生物传感器，包括形成在绝缘基板上的至少一对电极; 测量仪器，包括用于可拆卸地支撑生物传感器的支撑部件，电连接到电极的多个连接端子，以及通过连接端子向电极施加电压的驱动电源; 其中生物传感器被插入到测量仪器中，只有当生物传感器沿着指定的方向插入到测量仪器的支撑部分中时，生物传感器的电极中的任一个连接到精细到测量仪器的第一和第二连接端子，并且 具有电极结构，以在由驱动电源施加电压时允许第一连接端子与第二连接端子导通。
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