公开(公告)号：US09884913B2

公开(公告)日：2018-02-06

申请号：US15462585

申请日：2017-03-17

Applicant: Novartis AG ,  DANA-FARBER CANCER INSTITUTE, INC. ,  Children's Medical Center Corporation

Inventor： Catherine Anne Sabatos-Peyton ,  Barbara Brannetti ,  Alan S. Harris ,  Thomas Huber ,  Thomas Pietzonka ,  Jennifer Marie Mataraza ,  Walter A. Blattler ,  Daniel J. Hicklin ,  Maximiliano Vasquez ,  Rosemarie H. DeKruyff ,  Dale T. Umetsu ,  Gordon James Freeman ,  Tiancen Hu ,  John A. Taraszka ,  Fangmin Xu

IPC: C07K16/28 ,  A61K39/395 ,  A61K45/06 ,  G01N33/68

CPC classification number: C07K16/2803 ,  A61K39/3955 ,  A61K39/39558 ,  A61K45/06 ,  C07K2299/00 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/52 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  G01N33/6893

Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.

公开(公告)号：US09605070B2

公开(公告)日：2017-03-28

申请号：US14610837

申请日：2015-01-30

Applicant: Novartis AG ,  DANA-FARBER CANCER INSTITUTE, INC. ,  Children's Medical Center Corporation

Inventor： Catherine Anne Sabatos-Peyton ,  Barbara Brannetti ,  Alan S. Harris ,  Thomas Huber ,  Thomas Pietzonka ,  Jennifer Marie Mataraza ,  Walter A. Blattler ,  Daniel J. Hicklin ,  Maximiliano Vasquez ,  Rosemarie H. DeKruyff ,  Dale T. Umetsu ,  Gordon James Freeman ,  Tiancen Hu ,  John A. Taraszka ,  Fangmin Xu

IPC: C07K16/28 ,  A61K39/395 ,  A61K45/06

CPC classification number: C07K16/2803 ,  A61K39/3955 ,  A61K39/39558 ,  A61K45/06 ,  C07K2299/00 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/52 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  G01N33/6893

Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.