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公开(公告)号:US08242271B2
公开(公告)日:2012-08-14
申请号:US12132537
申请日:2008-06-03
IPC分类号: C07D403/12 , C07D403/14 , C07D401/12 , C07D401/14 , A61K31/506 , A61P35/00 , A61P19/02
CPC分类号: C07D401/04 , A61K31/444 , A61K31/506 , A61K45/06 , C07D401/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
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公开(公告)号:US20100016296A1
公开(公告)日:2010-01-21
申请号:US12426495
申请日:2009-04-20
IPC分类号: A61K31/538 , C07D413/12 , C12N9/99 , C07D495/06 , C12Q1/48 , G01N33/00
CPC分类号: A61K31/505 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D239/47 , C07D239/48 , C07D401/12 , C07D403/12 , C07D413/12 , C07D487/04 , C07D495/04 , Y02P20/582
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
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公开(公告)号:US20120190614A1
公开(公告)日:2012-07-26
申请号:US13443847
申请日:2012-04-10
申请人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
发明人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
IPC分类号: A61K38/06 , C07K5/107 , C07K5/083 , A61P31/12 , A61K38/07 , C12N9/96 , A61P31/14 , C07K5/09 , C07K5/023
CPC分类号: C07K7/06 , A61K31/40 , A61K31/403 , A61K31/4439 , A61K31/4965 , A61K31/506 , A61K38/00 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/52 , C07D401/12 , C07D403/12 , C07K5/06165 , C07K5/0802 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0817 , C07K5/0819 , C07K5/0821 , C07K5/0827 , C07K5/1016 , C12N9/506 , C12N9/99 , C12Y304/21098
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
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公开(公告)号:US08188137B2
公开(公告)日:2012-05-29
申请号:US12541347
申请日:2009-08-14
申请人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
发明人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
IPC分类号: A61K31/40 , C07D209/52
CPC分类号: C07K7/06 , A61K31/40 , A61K31/403 , A61K31/4439 , A61K31/4965 , A61K31/506 , A61K38/00 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/52 , C07D401/12 , C07D403/12 , C07K5/06165 , C07K5/0802 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0817 , C07K5/0819 , C07K5/0821 , C07K5/0827 , C07K5/1016 , C12N9/506 , C12N9/99 , C12Y304/21098
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
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公开(公告)号:US20110269244A1
公开(公告)日:2011-11-03
申请号:US12982352
申请日:2010-12-30
申请人: Russell C. Petter , Charles F. Jewell , Kwangho Lee , Aravind Prasad Medikonda , Deqiang Niu , Lixin Qiao , Juswinder Singh , Zhendong Zhu
发明人: Russell C. Petter , Charles F. Jewell , Kwangho Lee , Aravind Prasad Medikonda , Deqiang Niu , Lixin Qiao , Juswinder Singh , Zhendong Zhu
CPC分类号: C12N9/96 , C07D207/16 , C07D239/49 , C07D401/04 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D417/06 , C07D417/14 , C07D487/04 , C07D491/08 , C07D493/04 , C07D495/04 , C07D513/04 , C07D519/00 , C12N9/12 , C12N9/506 , C12N9/93 , C12Q1/25 , C12Q1/37 , C12Q1/485 , C12Y207/11001 , C12Y304/21098 , C12Y603/02 , G01N33/68 , G16B15/00 , G16C20/50
摘要: The present invention relates to enzyme inhibitors. More specifically, the present invention relates to ligand-directed covalent modification of proteins; method of designing same; pharmaceutical formulation of same; and method of use.
摘要翻译: 本发明涉及酶抑制剂。 更具体地,本发明涉及蛋白质的配体定向共价修饰; 设计方法 药物制剂相同; 和使用方法。
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公开(公告)号:US20100041674A1
公开(公告)日:2010-02-18
申请号:US12541347
申请日:2009-08-14
申请人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
发明人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
IPC分类号: A61K31/4965 , C07D207/08 , C07D209/52 , C07D401/02 , C07D403/02 , A61K31/40 , A61K31/403 , A61K31/4439 , A61K31/506
CPC分类号: C07K7/06 , A61K31/40 , A61K31/403 , A61K31/4439 , A61K31/4965 , A61K31/506 , A61K38/00 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/52 , C07D401/12 , C07D403/12 , C07K5/06165 , C07K5/0802 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0817 , C07K5/0819 , C07K5/0821 , C07K5/0827 , C07K5/1016 , C12N9/506 , C12N9/99 , C12Y304/21098
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
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公开(公告)号:US08524760B2
公开(公告)日:2013-09-03
申请号:US13443847
申请日:2012-04-10
申请人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
发明人: Deqiang Niu , Russell C. Petter , Lixin Qiao , Juswinder Singh
IPC分类号: A61K31/40 , C07D209/52
CPC分类号: C07K7/06 , A61K31/40 , A61K31/403 , A61K31/4439 , A61K31/4965 , A61K31/506 , A61K38/00 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/52 , C07D401/12 , C07D403/12 , C07K5/06165 , C07K5/0802 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0817 , C07K5/0819 , C07K5/0821 , C07K5/0827 , C07K5/1016 , C12N9/506 , C12N9/99 , C12Y304/21098
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
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公开(公告)号:US09238629B2
公开(公告)日:2016-01-19
申请号:US13286062
申请日:2011-10-31
申请人: Kwangho Lee , Deqiang Niu , Russell C. Petter , Juswinder Singh
发明人: Kwangho Lee , Deqiang Niu , Russell C. Petter , Juswinder Singh
IPC分类号: A61K31/505 , C07D239/48 , C07D239/47 , A61K31/16 , A61K31/506 , A61K45/06
CPC分类号: C07D239/48 , A61K31/16 , A61K31/505 , A61K31/506 , A61K45/06 , C07D239/47 , A61K2300/00
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
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公开(公告)号:US20120149722A1
公开(公告)日:2012-06-14
申请号:US13286062
申请日:2011-10-31
申请人: Kwangho Lee , Deqiang Niu , Russell C. Petter , Juswinder Singh
发明人: Kwangho Lee , Deqiang Niu , Russell C. Petter , Juswinder Singh
IPC分类号: A61K31/505 , C12N5/071 , A61P35/00 , C07D239/48 , C07D239/47
CPC分类号: C07D239/48 , A61K31/16 , A61K31/505 , A61K31/506 , A61K45/06 , C07D239/47 , A61K2300/00
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
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公开(公告)号:US20120258967A1
公开(公告)日:2012-10-11
申请号:US13414918
申请日:2012-03-08
申请人: Lixin Qiao , Deqiang Niu , Russell C. Petter , Zhengdong Zhu
发明人: Lixin Qiao , Deqiang Niu , Russell C. Petter , Zhengdong Zhu
IPC分类号: A61K31/5377 , A61P37/00 , A61P29/00 , A61P35/00 , A61P19/00 , A61P3/00 , A61P25/00 , A61P25/28 , A61P9/00 , A61P37/08 , A61P11/06 , A61P5/00 , C12N9/99 , C12N9/96 , C12Q1/48 , C07D413/14
CPC分类号: C07D401/04 , C07D401/14 , C07D413/14 , C07D417/14
摘要: The present invention provides compounds, compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其组合物及其使用方法。
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