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公开(公告)号:US09308399B2
公开(公告)日:2016-04-12
申请号:US13582115
申请日:2010-03-11
IPC分类号: A61Q11/00 , A61K8/22 , A61K8/25 , A61K6/00 , A61K33/40 , A61Q11/02 , A61K8/31 , A61K8/49 , A61K8/81 , A61K8/891
CPC分类号: A61Q11/00 , A61K8/22 , A61K8/31 , A61K8/4913 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要: A tooth whitening composition for whitening a surface of a tooth, the composition comprising a mixture of a whitening agent comprising an aqueous peroxide, a hydrophobic polymer carrier for adhering the tooth whitening composition to a tooth surface and at least one adhesion enhancing agent.
摘要翻译: 一种用于使牙齿表面美白的牙齿美白组合物,所述组合物包含含有过氧化氢的增白剂,用于将牙齿增白组合物粘附到牙齿表面的疏水聚合物载体和至少一种粘合增强剂的混合物。
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公开(公告)号:US20090202456A1
公开(公告)日:2009-08-13
申请号:US12058387
申请日:2008-03-28
申请人: Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人: Michael Prencipe , Guofeng Xu , Ravi Subramanyam , Donghui Wu , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
IPC分类号: A61K8/44 , A61K31/195 , A61Q11/00
CPC分类号: A61K8/44 , A61K8/463 , A61K8/55 , A61K8/8164 , A61K31/198 , A61Q11/00
摘要: The invention relates to novel arginine salts, compositions comprising them, and their uses.
摘要翻译: 本发明涉及新颖的精氨酸盐,包含它们的组合物及其用途。
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公开(公告)号:US20090202455A1
公开(公告)日:2009-08-13
申请号:US12058360
申请日:2008-03-28
申请人: Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人: Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
摘要: This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
摘要翻译: 本发明涉及口腔护理组合物,其包含有效量的碱性氨基酸盐,该盐在无缓冲溶液中的pH值小于约7.5; 有效量的可溶性氟化物盐; 以及具有小于约7.5的无缓冲溶液中的pH的颗粒材料; 以及使用和制备这种组合物的方法。
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公开(公告)号:US20080274065A1
公开(公告)日:2008-11-06
申请号:US12028782
申请日:2008-02-08
申请人: Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人: Richard Scott Robinson , Richard J. Sullivan , Michael Prencipe , Rajnish Kohli , Isabelle Van Rycke , Richard Lovell , Sergio Leite , Eric A. Simon , Ralph Peter Santarpia , Diane Cummins , Sarita V. Mello , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
CPC分类号: A61K8/25 , A61K8/44 , A61K2800/28 , A61K2800/412 , A61K2800/88 , A61Q11/00
摘要: The invention includes methods of cleaning an oral surface, maintaining oral health and/or increasing oral health. Such methods encompass contacting an oral surface with a primary oral care composition at least once daily, contacting the oral surface with a periodic oral care maintenance composition at least once monthly, wherein the periodic oral care maintenance composition comprises a basic amino acid, in free or salt form and optionally contacting the oral surface with a periodic oral care cleaning composition at least once monthly. The periodic oral care cleaning compositions suitable for use in the method comprise an abrasive system.
摘要翻译: 本发明包括清洁口腔表面,维持口腔健康和/或增加口腔健康的方法。 这样的方法包括每天至少一次使口腔表面与主要口腔护理组合物接触,使口腔表面与定期的口腔护理维持组合物每月至少一次接触,其中定期口腔护理维持组合物包含游离或 任选地使口腔表面与定期的口腔护理清洁组合物每月至少一次接触。 适用于该方法的定期口腔护理清洁组合物包括研磨系统。
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公开(公告)号:US20120328535A1
公开(公告)日:2012-12-27
申请号:US13582115
申请日:2010-03-11
CPC分类号: A61Q11/00 , A61K8/22 , A61K8/31 , A61K8/4913 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要: A tooth whitening composition for whitening a surface of a tooth, the composition comprising a mixture of a whitening agent comprising an aqueous peroxide, a hydrophobic polymer carrier for adhering the tooth whitening composition to a tooth surface and at least one adhesion enhancing agent.
摘要翻译: 一种用于使牙齿表面美白的牙齿美白组合物,所述组合物包含含有过氧化氢的增白剂,用于将牙齿增白组合物粘附到牙齿表面的疏水聚合物载体和至少一种粘合增强剂的混合物。
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公开(公告)号:US20090202451A1
公开(公告)日:2009-08-13
申请号:US12058424
申请日:2008-03-28
申请人: Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
发明人: Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
CPC分类号: A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.
摘要翻译: 本发明涉及包含碱性氨基酸或其盐和小颗粒级分的口腔护理组合物以及使用和制备这些组合物的方法。
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公开(公告)号:US20090202450A1
公开(公告)日:2009-08-13
申请号:US12058278
申请日:2008-03-28
申请人: Michael Prencipe , Diane Cummins , Ravi Subramanayam , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Donghui Wu , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人: Michael Prencipe , Diane Cummins , Ravi Subramanayam , Richard J. Sullivan , Ralph Peter Santarpia, III , Sarita V. Mello , Lynette Zaidel , Suman Chopra , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Donghui Wu , Andre M. Morgan , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要: This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an anionic surfactant, and to methods of using and of making such compositions.
摘要翻译: 本发明涉及包含游离或盐形式的有效量的碱性氨基酸以及阴离子表面活性剂的口腔护理组合物,以及使用和制备这些组合物的方法。
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公开(公告)号:US20060275225A1
公开(公告)日:2006-12-07
申请号:US11403732
申请日:2006-04-13
申请人: Michael Prencipe , Suman Chopra , Joseph Norris , Adolfo Serrano
发明人: Michael Prencipe , Suman Chopra , Joseph Norris , Adolfo Serrano
IPC分类号: A61K8/22
CPC分类号: A61C19/066 , A46B9/005 , A46B9/021 , A46B9/025 , A46B11/0024 , A46B11/0027 , A46B17/04 , A46B2200/10 , A46B2200/1046 , A46B2200/20 , A61C1/0092 , A61C3/005 , A61C17/0202 , A61C19/063 , A61K8/22 , A61K8/8147 , A61K2800/87 , A61K2800/92 , A61Q11/00
摘要: The method of the present invention is directed to the storage and dispensing of a peroxide containing tooth whitening composition. During storage and subsequent use the composition in the storage chamber must be maintained segregated from the applicator surface. This is accomplished by delivering the peroxide containing tooth whitening composition from the storage chamber through a delivery channel having a length and a cross-sectional diameter sufficient to preclude the migration of moisture and the enzyme catalase from the application surface to the storage chamber. The composition is applied to teeth by means of bristles, a sponge surface or fibrillated surface. This applicator can be used with both aqueous and non-aqueous peroxide containing tooth whitening compositions.
摘要翻译: 本发明的方法涉及含过氧化物的牙齿增白组合物的储存和分配。 在储存和随后使用期间,储存室中的组合物必须保持与施用器表面分离。 这是通过将来自储存室的含过氧化物的牙齿增白组合物通过具有足以防止水分和酶过氧化氢酶从施用表面迁移到储存室的长度和横截面直径的输送通道来实现的。 组合物通过刷毛,海绵表面或原纤化表面施加到牙齿上。 该施用器可以与含水和非水过氧化物含有牙齿美白组合物一起使用。
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公开(公告)号:US20060045854A1
公开(公告)日:2006-03-02
申请号:US10929087
申请日:2004-08-27
IPC分类号: A61K8/22
CPC分类号: A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
摘要: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
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公开(公告)号:US20050038181A1
公开(公告)日:2005-02-17
申请号:US10642458
申请日:2003-08-15
申请人: Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
发明人: Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
CPC分类号: A61K8/22 , A61C19/066 , A61K8/8176 , A61K8/891 , A61Q11/00
摘要: A stable, nonaqueous liquid tooth whitening composition comprised of an anhydrous peroxide compound dispersed in an orally acceptable hydrophobic organic material such as a silicone based pressure sensitive polymer which composition when applied topically to tooth surfaces forms an adherent layer containing the peroxide compound which peroxide compound is thereafter is released from the layer to effect tooth whitening.
摘要翻译: 一种稳定的非水液体牙齿增白组合物,其由分散在口腔可接受的疏水性有机材料如硅氧烷基压敏聚合物中的无水过氧化物组合物组成,该组合物当局部施用于牙齿表面时形成含有过氧化物化合物的粘附层, 此后从该层释放以实现牙齿美白。
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