MEASUREMENT METHOD FOR PHYSIOLOGICALLY ACTIVE SUBSTANCE OF BIOLOGICAL ORIGIN, AND REAGENT KIT FOR MEASUREMENT
    21.
    发明申请
    MEASUREMENT METHOD FOR PHYSIOLOGICALLY ACTIVE SUBSTANCE OF BIOLOGICAL ORIGIN, AND REAGENT KIT FOR MEASUREMENT 审中-公开
    生物原始生理活性物质的测量方法和测量试剂盒的测量方法

    公开(公告)号:US20130052657A1

    公开(公告)日:2013-02-28

    申请号:US13580638

    申请日:2010-02-26

    申请人: Katsumi Yabusaki

    发明人: Katsumi Yabusaki

    IPC分类号: G01N33/579 G01N21/82

    CPC分类号: G01N33/579 G01N33/551

    摘要: Disclosed is a technique which simplifies the adjustment of a reagent which makes the proteins contained in limulus amoebocyte lysate (LAL) attach to the surface of microparticles dispersed in a prepared drug solution, and which can improve the accuracy of the detection of a predetermined physiologically active substance or the measurement of the concentration thereof. A reagent is prepared which adsorbs the proteins contained in LAL to beads dispersed in a drug solution prepared in advance. By reacting a sample containing an endotoxin with the reagent, groups of the beads associate and rapidly form large aggregates, and measurement of the endotoxin is carried out by the detecting the formation of the aggregates. The beads are formed from an inorganic material such as alumina, kaolin, or manganese oxide.

    摘要翻译: 公开了一种简化使鲎变形细胞裂解物(LAL)中含有的蛋白质附着于分散在制备药液中的微粒表面的试剂调整的技术,能够提高预定的生理活性物质的检测精度 物质或其浓度的测量。 制备将LAL中包含的蛋白质吸附到预先制备的药物溶液中的珠粒的试剂。 通过使含有内毒素的样品与试剂反应,珠的组合并快速形成大的聚集体,并且通过检测聚集体的形成来进行内毒素的测量。 珠粒由无机材料如氧化铝,高岭土或氧化锰形成。

    Boron removal method utilizing sugar amide derivative
    22.
    发明授权
    Boron removal method utilizing sugar amide derivative 失效
    使用糖酰胺衍生物的硼去除方法

    公开(公告)号:US08236180B2

    公开(公告)日:2012-08-07

    申请号:US12600215

    申请日:2008-05-21

    申请人: Katsumi Yabusaki

    发明人: Katsumi Yabusaki

    IPC分类号: C02F1/28

    摘要: Disclosed is a boron adsorbent having an excellent adsorbing ability against boron contained in a solution, which is inexpensive and has high general versatility. Also disclosed is a boron removal method which can remove boron efficiently in a simple manner. An amide derivative represented by the general formula (1) is added to a boron-containing water under alkaline conditions to cause the adsorption of boron to the amide derivative. Then, a cation source having two or more valencies is added to the water to cause the aggregation of the amide body. The aggregated amide body is removed from the water. In the general formula (1), m represents 1 or 2; X represents —CH2OH, —CHO or —COOH; n represents an integer of 2 to 5; X are independent from each other and n are independent from each other when m represents 2; and Y represents a monovalent hydrocarbon group having 6 to 16 carbon atoms when m is 1, and represents a divalent hydrocarbon group having 8 to 18 carbon atoms when m is 2.

    摘要翻译: 公开了一种对于溶液中含有的硼的吸附能力优异的硼吸附剂,其成本低廉且通用性高。 还公开了能够以简单的方式有效去除硼的硼去除方法。 在碱性条件下,将通式(1)表示的酰胺衍生物加入到含硼水中,使硼吸附到酰胺衍生物上。 然后,将具有两个或更多个价态的阳离子源加入到水中以引起酰胺体的聚集。 聚集的酰胺体从水中除去。 在通式(1)中,m表示1或2; X表示-CH 2 OH,-CHO或-COOH; n表示2〜5的整数, X彼此独立,当m表示2时,n彼此独立; 而当m为1时,Y表示碳原子数为6〜16的一价烃基,m为2时,表示碳原子数为8〜18的二价烃基。

    Metal indicator
    23.
    发明授权
    Metal indicator 失效
    金属指示器

    公开(公告)号:US07648839B2

    公开(公告)日:2010-01-19

    申请号:US11631096

    申请日:2005-06-21

    IPC分类号: G01N33/20

    CPC分类号: G01N31/22

    摘要: To provide a novel copper ion indicator which is less influenced by interfering metal ions and which is useful for measurement of copper ion within a wide concentration range.The invention provides a copper ion indicator containing a compound represented by formula (1): [wherein each of R1, R2, R3, R4, R5, and R6 represents a hydrogen atom or an alkali metal atom], and a method for determining copper ion concentration, which employs the indicator.

    摘要翻译: 提供一种新颖的铜离子指示剂,其受干扰金属离子的影响较小,可用于在宽浓度范围内测量铜离子。 本发明提供一种含有式(1)表示的化合物的铜离子指示剂:其中R 1,R 2,R 3,R 4,R 5和R 6各自表示氢原子或碱金属原子],以及铜 离子浓度,采用指示剂。

    Method for measuring endotoxin and reagent kit for measuring endotoxin
    25.
    发明授权
    Method for measuring endotoxin and reagent kit for measuring endotoxin 有权
    测量内毒素的方法和用于测量内毒素的试剂盒

    公开(公告)号:US08211651B2

    公开(公告)日:2012-07-03

    申请号:US12809337

    申请日:2008-12-18

    申请人: Katsumi Yabusaki

    发明人: Katsumi Yabusaki

    IPC分类号: G01N33/53

    摘要: A technique which is less likely to be affected by turbid or color of samples and with which prompt and simple detection or concentration measurement of endotoxin can be achieved is provided. A reagent in which proteins contained in LAL are adsorbed or bound onto fine particles dispersed in a previously prepared drug liquid is prepared, and this reagent and a sample containing endotoxin are mixed. By doing this, endotoxin acts on the proteins on the fine particles and the fine particles are associated with one another to form a large aggregate at an early stage. By optically measuring the formation of this aggregate, detection or concentration measurement of endotoxin is performed.

    摘要翻译: 提供了不太可能受到样品的混浊或颜色影响的技术,并且可以实现对内毒素的即时和简单的检测或浓度测量。 准备将LAL中含有的蛋白质吸附或结合到分散在预先制备的药液中的微粒子上的试剂,并将该试剂和含有内毒素的试样混合。 通过这样做,内毒素作用于细颗粒上的蛋白质,并且细颗粒彼此相关联以在早期形成大的聚集体。 通过光学测量该聚集体的形成,进行内毒素的检测或浓度测定。

    Phosphoric ester of cellulose derivative and metal adsorbent comprising the same
    27.
    发明授权
    Phosphoric ester of cellulose derivative and metal adsorbent comprising the same 失效
    纤维素衍生物的磷酸酯和包含它的金属吸附剂

    公开(公告)号:US07741424B2

    公开(公告)日:2010-06-22

    申请号:US11575098

    申请日:2005-09-26

    摘要: The present invention is directed to a phosphoric ester of 2,3-dihydroxypropyl cellulose or 3-(2,3-dihydroxypropoxy)-2-hydroxypropyl cellulose, the cellulose having optionally undergone partial carbamidation, and to a metal absorbent employing the ester, and to a metal-absorbing apparatus employing the metal adsorbent.The cellulose derivative phosphoric ester serves as a metal adsorbent which exhibits high metal adsorption performance and metal adsorption rate per unit weight; has high mechanical strength; effectively soften water or a similar liquid; removes heavy metals from wastewater or a similar liquid at remarkably high efficiency; has excellent processability and can be formed into a variety of shapes and thus is applicable within a wide range; and can readily be reutilized.

    摘要翻译: 本发明涉及2,3-二羟基丙基纤维素或3-(2,3-二羟基丙氧基)-2-羟丙基纤维素的磷酸酯,该纤维素任选经历部分氨基甲酰化,以及使用该酯的金属吸收剂,以及 涉及使用金属吸附剂的金属吸收装置。 纤维素衍生物磷酸酯用作金属吸附剂,其具有高的金属吸附性能和每单位重量的金属吸附速率; 机械强度高; 有效地软化水或类似液体; 以非常高的效率从废水或类似液体中除去重金属; 具有优异的加工性,可以形成多种形状,因此适用范围广泛; 并且可以容易地重新利用。