公开(公告)号：US20080272779A1

公开(公告)日：2008-11-06

申请号：US11915626

申请日：2006-05-24

申请人： Hannes Dahnke ,  Tobias Schaeffter

发明人： Hannes Dahnke ,  Tobias Schaeffter

IPC分类号： G01R33/50

CPC分类号： G01R33/5601 ,  G01R33/50

摘要： MR based molecular imaging is used for the quantification of contrast agent concentrations. According to an exemplary embodiment of the present invention, a difference between R2 and R2* relaxation rates of a contrast agent is determined on the basis of data measured after contrast agent application. This may provide for an in vivo information relating to a compartmentalization or binding status of the contrast agent, and thus may improve the significance of the examination result.

摘要翻译： 基于MR的分子成像用于定量造影剂浓度。 根据本发明的一个示例性实施方案，根据造影剂施用后测量的数据确定造影剂的R2和R2 *松弛率之间的差异。 这可以提供与造影剂的分隔或结合状态相关的体内信息，从而可以提高检查结果的重要性。

公开(公告)号：US20080200799A1

公开(公告)日：2008-08-21

申请号：US11912674

申请日：2006-04-25

申请人： Nicolaas Petrus Willard ,  Rene Theodorus Wegh ,  Jeroen Alphons Pikkemaat ,  Holger Gruell ,  Tobias Schaeffter ,  Rudolf Mathias Johannes Nicolaas Lamerichs

发明人： Nicolaas Petrus Willard ,  Rene Theodorus Wegh ,  Jeroen Alphons Pikkemaat ,  Holger Gruell ,  Tobias Schaeffter ,  Rudolf Mathias Johannes Nicolaas Lamerichs

IPC分类号： A61B5/055

CPC分类号： G01R33/5601 ,  A61K49/124 ,  G01R33/5605

摘要： The present invention provides a method MRI imaging. By applying a time modulation to the contrast enhancement of an MRI contrast agent, the method according to the invention leads to images with improved signal-to-noise ratio in the contrast-enhanced areas, strongly suppressed unwanted signal in the unenhanced areas, and reduced artefacts, such as motion artefacts.

摘要翻译： 本发明提供一种MRI成像方法。 通过对MRI造影剂的对比度增强应用时间调制，根据本发明的方法导致对比度增强区域中具有改善的信噪比的图像，强烈地抑制未增强区域中的不需要的信号，并且减少 人造物，如运动文物。