公开(公告)号：US20180085320A1

公开(公告)日：2018-03-29

申请号：US15558636

申请日：2016-03-18

Applicant: The Regents of the University of California

Inventor： Liangfang Zhang ,  Weiwei Gao ,  Ronnie H. Fang ,  Che-Ming Jack Hu

IPC: A61K9/51 ,  A61K39/02

CPC classification number: A61K9/5176 ,  A61K9/5068 ,  A61K9/5192 ,  A61K31/427 ,  A61K31/43 ,  A61K31/49 ,  A61K31/545 ,  A61K39/02 ,  A61K45/06 ,  B82Y5/00 ,  Y02A50/401 ,  Y02A50/478 ,  Y02A50/48 ,  Y02A50/484 ,  A61K2300/00

Abstract: Nanoparticles are provided comprising an inner core comprising a non-cellular material, and an outer surface comprising a bacterial membrane, e.g., a bacterial membrane derived from a bacteria outer membrane vesicle. Also provided are compositions, e.g., medicament delivery systems and pharmaceutical compositions, comprising the present nanoparticles. Also provided are uses of the present nanoparticles, pharmaceutical compositions and medicament delivery systems for treating and/or preventing a disease or condition, e.g., bacterial infection, in a subject.