公开(公告)号：US09554011B2

公开(公告)日：2017-01-24

申请号：US14922614

申请日：2015-10-26

申请人： Akihiro Iwamatsu

发明人： Akihiro Iwamatsu

IPC分类号： H04N1/04 ,  H04N1/028 ,  F21V8/00 ,  H04N1/00 ,  G02B27/09

CPC分类号： H04N1/0289 ,  G02B6/0016 ,  G02B6/0043 ,  G02B6/0046 ,  G02B27/0994 ,  H04N1/00795

摘要： A light irradiator includes a light source and a light guide to guide a light flux from the light source to an illumination area. The light guide has an incident surface, an emission surface and two side surfaces. The emission surface is located apart from a reading optical axis with an inclination relative to the reading optical axis. The following relations are satisfied: S1(x)≧S2(x) S1(L)>S2(L) wherein S1 represents a divided cross-sectional area near the reading optical axis and S2 represents a divided cross-sectional area far from the reading optical axis when a virtual cross-sectional area S parallel to the incident surface of the light guide is divided by a plane passing the center of the incident surface, formed by a direction perpendicular thereto and the incident surface and the main scanning direction; S (x) represents a virtual cross-sectional area distant from the incident surface of the light guide by x; L is a distance from the incident surface to the emission surface; and 0≦x

摘要翻译： 光照射器包括光源和光导，以将来自光源的光通量引导到照明区域。 光导具有入射表面，发射表面和两个侧表面。 发射表面相对于读取光轴具有相对于读取光轴的倾斜度。 满足以下关系：S1（x）≥S2（x）S1（L）> S2（L）其中S1表示读取光轴附近的分割横截面积，S2表示远离 当与导光体的入射表面平行的虚拟横截面面积S除以通过入射表面的中心的平面，由与其垂直的方向和入射面和主扫描方向形成的平面读取光轴; S（x）表示与光导入射面远离x的虚拟横截面积; L是从入射表面到发射表面的距离; 0＆nlE; x

公开(公告)号：US07972788B2

公开(公告)日：2011-07-05

申请号：US12064602

申请日：2006-08-22

申请人： Satoshi Miyata ,  Kaoru Miyazaki ,  Chie Yasuda ,  Akihiro Iwamatsu

发明人： Satoshi Miyata ,  Kaoru Miyazaki ,  Chie Yasuda ,  Akihiro Iwamatsu

IPC分类号： C12Q1/68 ,  G01N33/53 ,  C07K1/00 ,  C07K14/00 ,  C07K17/00 ,  A61K38/17 ,  C08H1/06

CPC分类号： C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5023 ,  G01N33/6881

摘要： It is an object of the present invention to find substances that can be used as skin aging markers, and the present invention provides a method for determining the degree of skin aging, including measurement of expression of secretory proteins and/or intracellular proteins and/or their genes in skin cells and/or skin tissues, wherein the secretory proteins and/or intracellular proteins change their expression with aging of skin. The present invention also provides a kit for determining the degree of skin aging and a method for identifying substances effective in the prevention of skin aging.

摘要翻译： 本发明的目的是找到可用作皮肤老化标记的物质，本发明提供了一种测定皮肤老化程度的方法，包括测定分泌蛋白和/或细胞内蛋白质的表达和/或 它们在皮肤细胞和/或皮肤组织中的基因，其中分泌蛋白和/或细胞内蛋白质随着皮肤老化而改变其表达。 本发明还提供了用于确定皮肤老化程度的试剂盒以及用于鉴定有效预防皮肤老化的物质的方法。

公开(公告)号：US07820396B2

公开(公告)日：2010-10-26

申请号：US12090644

申请日：2006-10-19

申请人： Satoshi Miyata ,  Kaoru Miyazaki ,  Chie Yasuda ,  Akihiro Iwamatsu ,  Zenro Ikezawa ,  Michiko Aihara ,  Kayano Moriyama

发明人： Satoshi Miyata ,  Kaoru Miyazaki ,  Chie Yasuda ,  Akihiro Iwamatsu ,  Zenro Ikezawa ,  Michiko Aihara ,  Kayano Moriyama

IPC分类号： G01N33/53 ,  G01N33/567

CPC分类号： G01N33/6881 ,  C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N2800/202

摘要： It is an object of the present invention to find substances that can be used as disease markers for atopic dermatitis and the present invention provides a method for determining atopic dermatitis, including measurement of the expression of specific proteins and/or their genes in skin cells and/or skin tissues, wherein the specific proteins change their expression with inflammation caused by atopic dermatitis or change their expression according to the degree of predisposition to atopic dermatitis. The present invention also provides a kit for determining the degree of inflammation of atopic dermatitis or risk of developing atopic dermatitis, as well as a method for determining substances effective in the treatment and/or prevention of atopic dermatitis.

摘要翻译： 本发明的目的是找到可用作特应性皮炎的疾病标志物的物质，本发明提供了一种确定特应性皮炎的方法，包括测定皮肤细胞中特异性蛋白质和/或其基因的表达， /或皮肤组织，其中特异性蛋白质根据特应性皮炎引起的炎症改变其表达，或根据对特应性皮炎的倾向程度改变其表达。 本发明还提供了用于确定特应性皮炎炎症程度或发展特应性皮炎风险的试剂盒，以及用于确定有效治疗和/或预防特应性皮炎的物质的方法。

公开(公告)号：US20090305242A1

公开(公告)日：2009-12-10

申请号：US12064602

申请日：2006-08-22

申请人： Satoshi Miyata ,  Kaoru Miyazaki ,  Chie Yasuda ,  Akihiro Iwamatsu

发明人： Satoshi Miyata ,  Kaoru Miyazaki ,  Chie Yasuda ,  Akihiro Iwamatsu

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5023 ,  G01N33/6881

摘要： It is an object of the present invention to find substances that can be used as skin aging markers, and the present invention provides a method for determining the degree of skin aging, including measurement of expression of secretory proteins and/or intracellular proteins and/or their genes in skin cells and/or skin tissues, wherein the secretory proteins and/or intracellular proteins change their expression with aging of skin. The present invention also provides a kit for determining the degree of skin aging and a method for identifying substances effective in the prevention of skin aging.

摘要翻译： 本发明的目的是找到可用作皮肤老化标记的物质，本发明提供了一种测定皮肤老化程度的方法，包括测定分泌蛋白和/或细胞内蛋白质的表达和/或 它们在皮肤细胞和/或皮肤组织中的基因，其中分泌蛋白和/或细胞内蛋白质随着皮肤老化而改变其表达。 本发明还提供了用于确定皮肤老化程度的试剂盒以及用于鉴定有效预防皮肤老化的物质的方法。

公开(公告)号：US20070087426A1

公开(公告)日：2007-04-19

申请号：US11526632

申请日：2006-09-26

申请人： Masaru Kato ,  Yutaka Miura ,  Masako Kettoku ,  Akihiro Iwamatsu ,  Kazuo Kobayashi ,  Toshihiro Komeda

发明人： Masaru Kato ,  Yutaka Miura ,  Masako Kettoku ,  Akihiro Iwamatsu ,  Kazuo Kobayashi ,  Toshihiro Komeda

IPC分类号： C12N9/10 ,  C07H21/04

CPC分类号： C12N9/2411 ,  C12N9/1048 ,  C12N9/2408 ,  C12N9/2414 ,  C12N9/2417 ,  C12P19/14

摘要： The invention provides a novel transferase that acts on a saccharide, as a substrate, composed of at least three sugar units wherein at least three glucose residues on the reducing end are linked α-1,4 so as to transfer the α-1,4 lingages to a α-1, α-1 linkages; a process for producing the transferase; a gene coding for the same; and a process for producing an oligosaccharide by using the same. Also provided are a novel amylase that has a principal activity of acting on a saccharide, as a substrate, composed of at least three sugar units wherein at least three sugar units on the reducing end side are glucose units and the linkage between the first and the second glucose units is α-1, α-1 while the linkage between the second and the third glucose units is α-1,4 so as to liberate α, α-trehalose by hydrolyzing the α-1,4 linkage and another activity of hydrolyzing the α-1,4 linkage within the molecular chain of the substrate and that liberates disaccharides and/or monosaccharides as the principal final products; a process for producing the amylase; a gene coding for the same; and a process for producing α, α-trehalose by using a combination of the transferase and the amylase.

摘要翻译： 本发明提供了一种新的转移酶，其作用为由至少三个糖单元组成的作为底物的糖，其中还原端上的至少三个葡萄糖残基与α-1,4连接以转移α-1,4 属于α-1，α-1键; 生产转移酶的方法; 编码相同的基因; 以及使用该寡糖的方法。 还提供了一种新的淀粉酶，其具有作用于由至少三个糖单元组成的糖类作为底物的主要活性，其中还原端侧的至少三个糖单元是葡萄糖单元，第一和第 第二葡萄糖单位是α-1，α-1，而第二和第三葡萄糖单元之间的连接是α-1,4，以便通过水解α-1,4键和另一种活性的α-1,4键来释放α，α-海藻糖 水解基质分子链内的α-1,4键，释放出二糖和/或单糖作为主要的最终产物; 淀粉酶的制造方法; 编码相同的基因; 以及通过使用转移酶和淀粉酶的组合产生α，α-海藻糖的方法。

公开(公告)号：US06225531B1

公开(公告)日：2001-05-01

申请号：US09094557

申请日：1998-06-15

申请人： Makoto Kakitani ,  Naoyuki Umemoto ,  Isao Ishida ,  Akihiro Iwamatsu ,  Masaaki Yoshikawa ,  Naoto Yamaoka

发明人： Makoto Kakitani ,  Naoyuki Umemoto ,  Isao Ishida ,  Akihiro Iwamatsu ,  Masaaki Yoshikawa ,  Naoto Yamaoka

IPC分类号： C12N1582

CPC分类号： C12N15/8282 ,  C07K14/415 ,  C07K14/705

摘要： A glucan elicitor receptor having an amino acid sequence as substantially shown in SEQ ID NO:1; DNA molecules containing nucleotide sequences coding for a glucan elicitor receptor having an amino acid sequence as substantially shown in SEQ ID NO:1, or fragments thereof; DNA molecules containing nucleotide sequences coding for a glucan elicitor receptor, which are incorporated in plasmid pER23-1, or fragments thereof; vectors containing the DNA molecules or fragments thereof; plant cells transformed with the DNA molecules or fragments thereof; a method for creating a plant having resistance to pathogenic fungi comprising incorporating the DNA sequence coding for a glucan elicitor receptor, or fragment thereof into a chromosome of a plant and expressing the gene in the plant; a plant having resistance to pathogenic fungi, the plant having the DNA molecule containing a nucleotide sequence coding for a glucan elicitor receptor, or its fragment transferred thereinto and expressing the gene; and methods for using the DNA molecule containing a nucleotide sequence coding for a glucan elicitor receptor, or fragment thereof.

摘要翻译： 具有基本上如SEQ ID NO：1所示的氨基酸序列的葡聚糖激发剂受体; 含有编码具有基本上如SEQ ID NO：1所示的氨基酸序列的葡聚糖激发剂受体的核苷酸序列的DNA分子或其片段; 含有编码葡聚糖激发剂受体的核苷酸序列的DNA分子，其掺入质粒pER23-1中，或其片段; 含有DNA分子或其片段的载体; 用DNA分子或其片段转化的植物细胞; 一种用于产生具有抗病原真菌的植物的方法，包括将编码葡聚糖激发剂受体或其片段的DNA序列掺入植物的染色体并在植物中表达该基因; 具有抗病原真菌的植物，所述植物具有含有编码葡聚糖激发剂受体的核苷酸序列的DNA分子，或其转移到其中并表达该基因的植物; 以及使用含有编码葡聚糖激发剂受体或其片段的核苷酸序列的DNA分子的方法。

公开(公告)号：US5728412A

公开(公告)日：1998-03-17

申请号：US465334

申请日：1995-06-05

申请人： Toshio Fujii ,  Akihiro Iwamatsu ,  Hiroyuki Yoshimoto ,  Toshitaka Minetoki ,  Takayuki Bogaki ,  Naoshi Nagasawa

发明人： Toshio Fujii ,  Akihiro Iwamatsu ,  Hiroyuki Yoshimoto ,  Toshitaka Minetoki ,  Takayuki Bogaki ,  Naoshi Nagasawa

IPC分类号： C12G1/02 ,  C12C11/00 ,  C12C11/02 ,  C12G1/022 ,  C12G3/02 ,  C12N1/19 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12R1/865 ,  A23L1/10 ,  A23L1/28 ,  C07H21/04 ,  C12N1/00 ,  C12N1/18 ,  C12N15/63

CPC分类号： C12C5/004 ,  C12C11/00 ,  C12C11/003 ,  C12C11/02 ,  C12C12/004 ,  C12C12/006 ,  C12C5/026 ,  C12G1/0203 ,  C12N9/1029

摘要： This invention disclosed herein provides an alcohol acetyl transferase ("AATase"), an AATase encoding gene and a yeast having an improved ester producing ability due to transformation with the AATase encoding gene, This invention also provides a process for producing an alcoholic beverage having an enriched ester flavor using the transformed yeast.

摘要翻译： 本发明公开了一种醇乙酰转移酶（“AATase”），AATase编码基因和由于用AATase编码基因转化而具有改进的酯生产能力的酵母。本发明还提供一种生产具有 使用转化的酵母富集酯味。

公开(公告)号：US5686284A

公开(公告)日：1997-11-11

申请号：US461621

申请日：1995-06-05

申请人： Toshio Fujii ,  Akihiro Iwamatsu ,  Hiroyuki Yoshimoto ,  Toshitaka Minetoki ,  Takayuki Bogaki ,  Naoshi Nagasawa

发明人： Toshio Fujii ,  Akihiro Iwamatsu ,  Hiroyuki Yoshimoto ,  Toshitaka Minetoki ,  Takayuki Bogaki ,  Naoshi Nagasawa

IPC分类号： C12G1/02 ,  C12C11/00 ,  C12C11/02 ,  C12G1/022 ,  C12G3/02 ,  C12N1/19 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12R1/865 ,  C07H21/04 ,  C12N9/00

CPC分类号： C12C5/004 ,  C12C11/00 ,  C12C11/003 ,  C12C11/02 ,  C12C12/004 ,  C12C12/006 ,  C12C5/026 ,  C12G1/0203 ,  C12N9/1029

摘要： This invention disclosed herein provides an alcohol acetyl transferase ("AATase"), an AATase encoding gene and a yeast having an improved ester producing ability due to transformation with the AATase encoding gene. This invention also provides a process for producing an alcoholic beverage having an enriched ester flavor using the transformed yeast.