公开(公告)号：US4879381A

公开(公告)日：1989-11-07

申请号：US22433

申请日：1987-03-06

申请人： Hiroshi Sadaki ,  Narita Hirokazu ,  Hiroyuki Imaizumi ,  Yoshinori Konishi ,  Takihiro Inaba ,  Tatsuo Hirakawa ,  Hideo Taki ,  Masaru Tai ,  Yasuo Watanabe ,  Isamu Saikawa

发明人： Hiroshi Sadaki ,  Narita Hirokazu ,  Hiroyuki Imaizumi ,  Yoshinori Konishi ,  Takihiro Inaba ,  Tatsuo Hirakawa ,  Hideo Taki ,  Masaru Tai ,  Yasuo Watanabe ,  Isamu Saikawa

IPC分类号： C07D501/24 ,  A61K31/545 ,  C07D20060101 ,  C07D501/04 ,  C07D501/18 ,  C07D501/20 ,  C07D501/38 ,  C07D501/40 ,  C07D501/46 ,  C07D501/56 ,  C07D501/57

CPC分类号： C07D501/46 ,  A61K31/545 ,  C07D501/38 ,  C07D501/56 ,  C07D501/57

摘要： Novel cephalosporins which has attached to the exomethylene group at the 3-position of the cephem ring a substituted or unsubstituted aryl, acylamino, aromatic heterocyclic, triazolyl or tetrazolyl group, said aromatic heterocyclic group being attached through a carbon-carbon bond and said triazolyl or tetrazolyl group being attached through a carbon-nitrogen bond, and has the following group attached to the amino group at the 7-position: ##STR1## wherein A represents a group of the formula, --CH.sub.2 -- or a group of the formula ##STR2## in which R.sup.5 represents a hydrogen atom or an alkyl group, and the bond represents syn or anti isomer or their mixture; R.sup.3 represents a hydrogen or halogen atom; and R.sup.4 represents a hydrogen atom or an amino group which may be protected or substituted. These cephalosporins have a broad antibacterial spectrum, are stable against .beta.-lactamase produced by bacteria, have a low toxicity, and are well absorbed when administered orally or parenterally.

摘要翻译： 在头孢烯环的3位连接到外亚甲基上的新型头孢菌素取代或未取代的芳基，酰氨基，芳族杂环，三唑基或四唑基，所述芳族杂环基通过碳 - 碳键连接，所述三唑基或 四唑基通过碳 - 氮键连接，并且具有与7-位上的氨基连接的下列基团：其中A表示下式的基团：-CH 2 - 或式 其中R 5表示氢原子或烷基，并且该键表示顺式或反式异构体或其混合物; R3表示氢或卤素原子; R4表示氢原子或可被保护或取代的氨基。 这些头孢菌素具有广泛的抗菌谱，对细菌产生的β-内酰胺酶是稳定的，具有低毒性，并且当口服或肠胃外给药时被良好吸收。

公开(公告)号：US4395412A

公开(公告)日：1983-07-26

申请号：US221622

申请日：1980-12-31

申请人： Isamu Saikawa ,  Shuntaro Takano ,  Hiroyuki Imaizumi ,  Isamu Takakura ,  Hirokazu Ochiai ,  Takashi Yasuda ,  Hideo Taki ,  Masaru Tai ,  Yutaka Kodama

发明人： Isamu Saikawa ,  Shuntaro Takano ,  Hiroyuki Imaizumi ,  Isamu Takakura ,  Hirokazu Ochiai ,  Takashi Yasuda ,  Hideo Taki ,  Masaru Tai ,  Yutaka Kodama

IPC分类号： C07D295/20 ,  C07D501/24 ,  C07D501/34 ,  C07D501/36 ,  C07D501/57 ,  A61K31/545

CPC分类号： C07D295/20 ,  Y02P20/55

摘要： A 7.alpha.-methoxycephalosporin represented by the general formula: ##STR1## wherein R.sup.1 represents a hydrogen atom or a carboxyl-protecting group; R.sup.2 represents an organic group linked to the carbon atom through an oxygen or sulfur atom; R.sup.3 represents a lower alkyl group; n is 0, 1 or 2; A represents a hydrogen atom or a substituted or unsubstituted alkyl group; and B represents a substituted or unsubstituted alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl or heterocyclic group, and a salt thereof. These compounds have a broad antibacterial spectrum, high resistance to .beta.-lactamase produced from bacteria, and an effective antibacterial activity against clinical isolates of bacteria.

公开(公告)号：US4263292A

公开(公告)日：1981-04-21

申请号：US81835

申请日：1979-10-04

申请人： Isamu Saikawa ,  Shuntaro Takano ,  Hiroyuki Imaizumi ,  Isamu Takakura ,  Hirokazu Ochiai ,  Takashi Yasuda ,  Hideo Taki ,  Masaru Tai ,  Yutaka Kodama

发明人： Isamu Saikawa ,  Shuntaro Takano ,  Hiroyuki Imaizumi ,  Isamu Takakura ,  Hirokazu Ochiai ,  Takashi Yasuda ,  Hideo Taki ,  Masaru Tai ,  Yutaka Kodama

IPC分类号： C07D241/08 ,  C07D295/20 ,  C07D501/57 ,  A61K31/545

CPC分类号： C07D241/08 ,  C07D295/20 ,  Y02P20/55

摘要： A 7.alpha.-methoxycephalosporin represented by the general formula and a salt thereof: ##STR1## wherein R.sup.1 represents a hydrogen atom or a carboxyl-protecting group; R.sup.2 represents an organic group linked to the carbon atoms through an oxygen or sulfur atom; R.sup.3 represents a lower alkyl group; n is 0, 1 or 2; A represents a hydrogen atom or a substituted or unsubstituted alkyl group; and B represents a substituted or unsubstituted alkyl group. These compounds have a broad antibacterial spectrum and high resistance to .beta.-lactamase produced from bacteria, and are well absorbed in a living body.

摘要翻译： 由通式表示的7α-甲氧头孢菌素及其盐：其中R 1表示氢原子或羧基保护基; R2表示通过氧或硫原子与碳原子连接的有机基团; R3表示低级烷基; n为0,1或2; A表示氢原子或取代或未取代的烷基; B表示取代或未取代的烷基。 这些化合物具有广泛的抗菌谱和对细菌产生的β-内酰胺酶的高抗性，并且在活体中被很好地吸收。

公开(公告)号：US07858172B2

公开(公告)日：2010-12-28

申请号：US12302257

申请日：2007-05-24

申请人： Hiroyuki Imaizumi ,  Yasushi Yamanaka ,  Kei Morimoto

发明人： Hiroyuki Imaizumi ,  Yasushi Yamanaka ,  Kei Morimoto

IPC分类号： B32B27/04

CPC分类号： B29C45/0005 ,  B29B9/14 ,  B29C47/0004 ,  B29C47/0009 ,  B29C70/12 ,  B29K2067/00 ,  B29K2067/006 ,  B29K2077/00 ,  B29K2105/06 ,  B29K2105/08 ,  C08J5/04 ,  C08J5/046 ,  C08J2367/02 ,  C08J2377/00 ,  C08K7/02 ,  Y10T428/249922 ,  Y10T428/24994 ,  Y10T428/249946

摘要： Provided is a fiber-reinforced thermoplastic resin molded article, which contains reinforcing fibers having a given flattened cross-sectional profile, in which the fiber length distribution of the reinforcing fibers is shifted on the side of long fibers, and which is excellent in mechanical strength, heat resistance, dimensional accuracy such as warpage resistance, and surface appearance.

摘要翻译： 本发明提供一种纤维增强热塑性树脂成型体，其含有具有给定的扁平截面形状的增强纤维，其中增强纤维的纤维长度分布在长纤维侧移动，机械强度优异 耐热性，抗翘曲性等尺寸精度和表面外观。

公开(公告)号：US20090304970A1

公开(公告)日：2009-12-10

申请号：US12440781

申请日：2007-09-07

申请人： Hiroyuki Imaizumi ,  Masayuki Akada ,  Ken Shimomai ,  Yoshihiro Kayano

发明人： Hiroyuki Imaizumi ,  Masayuki Akada ,  Ken Shimomai ,  Yoshihiro Kayano

IPC分类号： B60J1/00

CPC分类号： B60J1/007 ,  B29C45/062 ,  B29C45/14434 ,  B29C45/1615 ,  B29C2045/14893 ,  B29C2045/1682 ,  Y10T428/24479 ,  Y10T428/24777

摘要： The present invention relates to a panel-shaped molded product having a laminated structure which is produced from a resin and used for side doors, back doors, hoods, roofs, etc., and exhibits a more excellent finishing accuracy without occurrence of bleed-out along an inner periphery of a frame part and fine distortions on a design part. The panel-shaped molded product of the present invention is a molded product having a laminated structure which is obtained by injection-molding the frame part (2) on one surface of the plate-shaped design part (1) wherein an inner peripheral portion (4) of the frame part (2) is closely attached to the design part, and has a thickness changing region where a thickness of the frame part is reduced toward the side of a center of the frame part such that a ratio between a width of the thickness changing region and the thickness of the frame part (2), and a ratio between a width of the thickness changing region and a width of the frame part (2) are respectively adjusted to satisfy specific relationships.

摘要翻译： 本发明涉及一种具有层叠结构的面板状模制品，其由树脂制成并用于侧门，后门，罩，屋顶等，并且具有更优异的精加工精度而不发生渗出 沿着框架部分的内周边并且在设计部分上具有精细的变形。 本发明的板状成型品是具有层叠结构的成型体，其通过在框状部分（2）的一个表面上注射成型框体（2）而获得，其中内周部分 框架部分（2）的框架部分（4）紧密地附接到设计部分，并且具有厚度改变区域，其中框架部分的厚度朝向框架部分的中心侧减小，使得 分别调整厚度变化区域和框架部分（2）的厚度，以及厚度变化区域的宽度与框架部分（2）的宽度之间的比率以满足特定关系。

公开(公告)号：US07521016B2

公开(公告)日：2009-04-21

申请号：US10514315

申请日：2003-07-02

申请人： Yoshihiro Kayano ,  Akimasa Kaneishi ,  Hiroyuki Imaizumi

发明人： Yoshihiro Kayano ,  Akimasa Kaneishi ,  Hiroyuki Imaizumi

IPC分类号： B29C45/17

CPC分类号： B29C45/1732

摘要： An apparatus for introducing a pressurized gas includes a pressurized-gas supply-source, a plurality of measuring tanks, a first pressurized-gas supply-line, pressurized-gas supply valves in the first pressurized-gas supply-line, second pressurized-gas supply-lines and pressurized-gas discharge-control valves disposed in the second pressurized-gas supply-lines. A combination of the measuring tanks is determined on the basis of the amount of a pressurized gas required for forming a hollow portion in a molded article, and the pressurized-gas discharge-control valves disposed in the second pressurized-gas supply-lines are controlled on the basis of the above determination.

摘要翻译： 一种用于引入加压气体的装置包括加压气体供应源，多个测量罐，第一加压气体供应管线，第一加压气体供应管线中的加压气体供应阀，第二加压气体 设置在第二加压气体供给线路中的供给线路和加压气体排出控制阀。 基于在成型品中形成中空部所需的加压气体的量来确定测量罐的组合，并且控制设置在第二加压气体供给管线中的加压气体排出控制阀 在上述决定的基础上。

公开(公告)号：US06866811B2

公开(公告)日：2005-03-15

申请号：US09842255

申请日：2001-04-26

申请人： Yoshihiro Kayano ,  Hiroyuki Imaizumi ,  Kazuaki Ochiai

发明人： Yoshihiro Kayano ,  Hiroyuki Imaizumi ,  Kazuaki Ochiai

IPC分类号： B29C45/26 ,  B29C45/00 ,  B29C45/13 ,  B29C45/16 ,  B29C45/17 ,  B29L9/00 ,  B29L22/00

CPC分类号： B29C45/1704 ,  B29C45/1639 ,  B29C45/1705

摘要： An injection-molding apparatus comprises a mold assembly having a first-molten-resin injection portion for injecting a first molten thermoplastic resin into a cavity of the mold assembly, a second-molten-resin injection portion for injecting a second molten thermoplastic resin into the cavity, and a pressurized-fluid introducing portion for introducing a pressurized fluid into the second molten thermoplastic resin injected into the cavity. The injection-molding apparatus also comprises a first injection cylinder communicating with the first-molten-resin injection portion, and a second injection cylinder communicating with the second-molten-resin injection portion.

摘要翻译： 注射成型装置包括：模具组件，其具有用于将第一熔融热塑性树脂注射到模具组件的空腔中的第一熔融树脂注入部分，用于将第二熔融热塑性树脂注入到模具组件中的第二熔融树脂注射部分 空腔和用于将加压流体引入注入到空腔中的第二熔融热塑性树脂中的加压流体引入部分。 注射成型装置还包括与第一熔融树脂注射部分连通的第一注射圆筒和与第二熔融树脂注射部分连通的第二注射圆筒。

公开(公告)号：US06771823B2

公开(公告)日：2004-08-03

申请号：US09811923

申请日：2001-03-19

申请人： Shinichi Sakaida ,  Hiroyuki Imaizumi ,  Yoshiaki Shishikui ,  Yasuaki Kanatsugu ,  Wentao Zheng

发明人： Shinichi Sakaida ,  Hiroyuki Imaizumi ,  Yoshiaki Shishikui ,  Yasuaki Kanatsugu ,  Wentao Zheng

IPC分类号： G06K936

CPC分类号： H04N19/23

摘要： A method of coding and transmitting moving pictures includes the steps of coding an extended background image, coding parameters indicative of an image area within the extended background image, coding a foreground picture that is to be composed with a background picture corresponding to the image area indicated by the parameters, coding a defocus value indicative of an extent to which the background picture should blur, and transmitting the coded extended background image, the coded parameters, the coded foreground picture, and the coded defocus value as a data stream to a decoder side. Coding and transmitting of the defocus value makes it possible to defocus the background picture at the decoder end, thereby producing a composed image of the background picture and the foreground picture having natural appearance.

摘要翻译： 编码和发送运动图像的方法包括以下步骤：对扩展背景图像进行编码，编码指示扩展背景图像内的图像区域的参数，编码将与所指示的图像区域相对应的背景图片组成的前景图像 通过参数编码表示背景画面应该模糊的程度的散焦值，并将编码的扩展背景图像，编码参数，编码前景画面和编码散焦值作为数据流发送到解码器侧 。 散焦值的编码和发送使得可以在解码器端散焦背景图像，从而产生背景图像的合成图像和具有自然外观的前景图像。

公开(公告)号：US4736026A

公开(公告)日：1988-04-05

申请号：US879540

申请日：1986-06-24

申请人： Hiroyuki Imaizumi ,  Takihiro Inaba ,  Seishi Morita ,  Ryuko Takeno ,  Yoshiharu Murotani ,  Hirohiko Fukuda ,  Junichi Yoshida ,  Kiyoshi Tanaka ,  Shuntaro Takano ,  Isamu Saikawa

发明人： Hiroyuki Imaizumi ,  Takihiro Inaba ,  Seishi Morita ,  Ryuko Takeno ,  Yoshiharu Murotani ,  Hirohiko Fukuda ,  Junichi Yoshida ,  Kiyoshi Tanaka ,  Shuntaro Takano ,  Isamu Saikawa

IPC分类号： C07D501/48 ,  C07D277/20 ,  C07D277/40 ,  C07D501/06 ,  C07D501/46 ,  C07D501/56

CPC分类号： C07D277/587

摘要： The invention relates to a process for producing a cephalosporin of the formula ##STR1## by reacting the compound ##STR2## with the compound ##STR3## in the presence of boron trifluoride or a complex thereof.

摘要翻译： 本发明涉及通过在三氟化硼或其复合物存在下使化合物＆lt; IMAGE＆gt;（顺式异构体）与化合物＆lt; IMAGE＆gt;反应来制备式“头孢菌素”（顺式异构体）的方法。

公开(公告)号：US4673738A

公开(公告)日：1987-06-16

申请号：US654681

申请日：1984-09-26

申请人： Hiroshi Sadaki ,  Hirokazu Narita ,  Hiroyuki Imaizumi ,  Yoshinori Konishi ,  Takihiro Inaba ,  Tatsuo Hirakawa ,  Hideo Taki ,  Masaru Tai ,  Yasuo Watanabe ,  Isamu Saikawa

发明人： Hiroshi Sadaki ,  Hirokazu Narita ,  Hiroyuki Imaizumi ,  Yoshinori Konishi ,  Takihiro Inaba ,  Tatsuo Hirakawa ,  Hideo Taki ,  Masaru Tai ,  Yasuo Watanabe ,  Isamu Saikawa

IPC分类号： C07D501/24 ,  A61K31/545 ,  C07D20060101 ,  C07D501/04 ,  C07D501/18 ,  C07D501/20 ,  C07D501/38 ,  C07D501/40 ,  C07D501/46 ,  C07D501/56 ,  C07D501/57

CPC分类号： C07D501/46 ,  A61K31/545 ,  C07D501/38 ,  C07D501/56 ,  C07D501/57

摘要： This invention relates to novel 7-(substituted or unsubstituted amino)-3-substituted methyl-.DELTA..sup.3 -cephem-4-carboxylic acids in which a substituted or unsubstituted 1,2,4-triazolyl or 2-(1,2,3,4-tetrazolyl) group attaches to the exomethylene group at the 3-position of the cephem ring through a carbon-nitrogen bond. These cephalosporins are useful intermediates for producing various novel cephalosporins. Also, this invention concerns a process for producing a compound represented by the formula: ##STR1## which comprises reacting a compound represented by the formula: ##STR2## with an optionally substituted triazole or tetrazole in the presence of an acid or a complex of the acid in an organic solvent at 0.degree. to 80.degree. C.

摘要翻译： 本发明涉及新的7-（取代或未取代的氨基）-3-取代的甲基-D-三头孢烯-4-羧酸，其中取代或未取代的1,2,4-三唑基或2-（1,2,3 ，4-四唑基）基团通过碳 - 氮键连接在头孢烯环的3-位上的外亚甲基基团。 这些头孢菌素是生产各种新型头孢菌素的有用中间体。 此外，本发明涉及一种制备由下式表示的化合物的方法：该方法包括使下式表示的化合物与任选取代的三唑或四唑在酸或其复合物的存在下反应： 酸在有机溶剂中于0〜80℃