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30 条记录 (耗时 0.022 秒)

    Method for disinfection using a 1,n-bis(N.sup.5 -trifluoromethyl-phenyl-N.sup.1 -biguanido)-alkane
    21.
    发明授权
    Method for disinfection using a 1,n-bis(N.sup.5 -trifluoromethyl-phenyl-N.sup.1 -biguanido)-alkane 失效
    使用1，正 - 双（N5-三氟甲基 - 苯基-N1-双胍） - 烷烃消毒的方法

    公开(公告)号：US5478864A

    公开(公告)日：1995-12-26

    申请号：US306731

    申请日：1994-09-15

    申请人： Akira Nishihara ,  Akihiro Nakamura ,  Tsunetoshi Honda ,  Michio Harada ,  Maki Takizawa

    发明人： Akira Nishihara ,  Akihiro Nakamura ,  Tsunetoshi Honda ,  Michio Harada ,  Maki Takizawa

    IPC分类号： A01N47/44 ,  A61K31/155 ,  C07C279/26

    CPC分类号： A01N47/44 ,  A61K31/155 ,  C07C279/265

    摘要： A novel disinfectant is disclosed. Said disinfectant is a compound 1,n-bis(N.sup.5 -m-, or p-trifluoromethyl-phenyl-N.sup.1 -biguanido)-C.sub.3 -C.sub.10 -alkane. The m-trifluoro-C.sub.6 derivative is a known compound. The compounds of the present invention exhibit germicidal effect against Pseudomonas aeruginosa, Proteus vulgaris and Alcaligenes faecalis at concentrations of 1/4-1/8 of the effective concentration for chlorhexidine. Against other microorganisms, the compounds are effective at the same level as chlorhexidine.

    摘要翻译： 公开了一种新型消毒剂。 所述消毒剂是化合物1，正 - 双（N5-m-或对 - 三氟甲基 - 苯基-N1-双胍基）-C 3 -C 10 - 烷烃。 间三氟-C6衍生物是已知化合物。 本发明化合物对氯霉素（Pseudomonas aeruginosa），普通变形杆菌（Proteus vulgaris）和粪产碱杆菌（Alcaligenes faecalis）的浓度为氯己定的有效浓度的1 / 4-1 / 8显示出杀菌作用。 与其他微生物相比，化合物在与氯己定相同的水平上是有效的。

    Process for producing fluorine-containing compounds
    26.
    发明授权
    Process for producing fluorine-containing compounds 失效
    含氟化合物的制造方法

    公开(公告)号：US08350082B2

    公开(公告)日：2013-01-08

    申请号：US12734842

    申请日：2008-11-28

    申请人： Mitsuo Kurumaya ,  Tsunetoshi Honda ,  Kota Omori

    发明人： Mitsuo Kurumaya ,  Tsunetoshi Honda ,  Kota Omori

    IPC分类号： C07C51/58

    CPC分类号： C07C51/60 ,  C07B39/00 ,  C07C51/62 ,  C07C67/14 ,  C07C55/40 ,  C07C55/36 ,  C07C53/50 ,  C07C69/63 ,  C07C53/42

    摘要： This process for producing fluorine-containing compounds includes liquid-phase fluorination by introducing a raw material compound and fluorine gas into a solvent to replace hydrogen atoms in the raw material compound with fluorine atoms. More specifically, the process for producing fluorine-containing compounds includes (1) promoting fluorination by dissolving the raw material compound in anhydrous hydrofluoric acid and introducing into a liquid-phase fluorination solvent, or (2) promoting fluorination by dissolving the raw material compound in a perfluoro compound having a plurality of polar groups in a molecule thereof and introducing into a liquid-phase fluorination solvent. According to these processes, a fluorination reaction can be carried out at high yield and without containing hardly any isomers while using a hydrocarbon compound as is for the raw material.

    摘要翻译： 该含氟化合物的制造方法包括通过将原料化合物和氟气引入溶剂中来代替原料化合物中的氢原子用氟原子进行液相氟化。 更具体地说，制造含氟化合物的方法包括：（1）通过将原料化合物溶解在无水氢氟酸中并引入液相氟化溶剂来促进氟化，或（2）通过将原料化合物溶解于 在其分子中具有多个极性基团并引入液相氟化溶剂的全氟化合物。 根据这些方法，氟化反应可以以高产率进行，并且在使用原料的烃化合物的同时不含有几乎任何异构体。

    Method for producing trifluoromethanesulfonic anhydride
    27.
    发明授权
    Method for producing trifluoromethanesulfonic anhydride 失效
    制备三氟甲磺酸酐的方法

    公开(公告)号：US07741518B2

    公开(公告)日：2010-06-22

    申请号：US12064113

    申请日：2006-10-24

    申请人： Hiroyuki Yatsuyanagi ,  Hiroshi Koshiyama ,  Tsunetoshi Honda

    发明人： Hiroyuki Yatsuyanagi ,  Hiroshi Koshiyama ,  Tsunetoshi Honda

    IPC分类号： C07C303/00

    CPC分类号： C07C303/00 ,  C07C309/00

    摘要： This method for producing trifluoromethanesulfonic anhydride reacting trifluoromethanesulfonic acid with phosphorus pentoxide to produce trifluoromethanesulfonic anhydride, wherein hardening of the reaction solution due to polyphosphoric acid, which is produced as a byproduct, is prevented by using an excess amount of trifluoromethanesulfonic acid with respect to the phosphorus pentoxide.

    摘要翻译： 这种三氟甲磺酸酐与五氧化二磷反应生成三氟甲磺酸酐的方法，其中通过使用过量的三氟甲磺酸相对于磷来防止作为副产物产生的由多磷酸引起的反应溶液的硬化 五氧化物。

    POTASSIUM PERFLUOROALKANESULFONATE AND METHOD FOR PRODUCING THE SAME
    28.
    发明申请
    POTASSIUM PERFLUOROALKANESULFONATE AND METHOD FOR PRODUCING THE SAME 失效
    全氟卡波酸钾及其生产方法

    公开(公告)号：US20090143613A1

    公开(公告)日：2009-06-04

    申请号：US12063132

    申请日：2006-09-29

    申请人： Masakazu Uotani ,  Hiroyuki Yatsuyanagi ,  Tsunetoshi Honda

    发明人： Masakazu Uotani ,  Hiroyuki Yatsuyanagi ,  Tsunetoshi Honda

    IPC分类号： C07C309/06

    CPC分类号： C25B3/08 ,  C07C309/06

    摘要： This method for producing a potassium perfluoroalkanesulfonate includes an electrochemical fluorination step in which an alkanesulfonyl halide compound is subjected to electrochemical fluorination in anhydrous hydrogen fluoride, thereby to generate a production gas containing perfluoroalkanesulfonyl fluoride as the main component. In addition, for example, the methods may include a gas absorption step in which the production gas is reacted with an aqueous solution of potassium hydroxide, thereby to generate a gas absorbed solution containing potassium perfluoroalkanesulfonate, a purification step in which impurities such as potassium fluoride, potassium hydroxide, and potassium sulfate, are removed, and a concentration and collection step in which the aqueous solution from which the impurities are removed is concentrated and dried. In the electrochemical fluorination, for example, it is possible that the proton concentration in the reaction solution is maintained in the range of 150 to 1,500 ppm to suppress the formation of byproducts.

    摘要翻译： 这种生产全氟烷基磺酸钾的方法包括电化学氟化步骤，其中烷基磺酰卤化合物在无水氟化氢中进行电化学氟化，从而产生以全氟烷基磺酰氟为主要成分的生产气体。 此外，例如，可以举出气体吸收工序，其中生产气体与氢氧化钾水溶液反应，从而产生含有全氟烷基磺酸钾的气体吸收溶液，纯化步骤，其中杂质如氟化钾 ，氢氧化钾和硫酸钾，并且浓缩和干燥除去杂质的水溶液的浓缩和收集步骤。 在电化学氟化中，例如，反应溶液中的质子浓度可能保持在150〜1500ppm的范围内，以抑制副产物的形成。

    Bis-biguanide compound useful as a disinfectant
    29.
    发明授权
    Bis-biguanide compound useful as a disinfectant 失效
    双胍类化合物可用作消毒剂

    公开(公告)号：US5420350A

    公开(公告)日：1995-05-30

    申请号：US298300

    申请日：1994-09-01

    申请人： Akira Nishihara ,  Akihiro Nakamura ,  Tsunetoshi Honda ,  Michio Harada ,  Maki Takizawa

    发明人： Akira Nishihara ,  Akihiro Nakamura ,  Tsunetoshi Honda ,  Michio Harada ,  Maki Takizawa

    IPC分类号： A01N47/44 ,  A61K31/155 ,  A61P31/04 ,  C07C279/26 ,  C07C279/06 ,  A01N37/52 ,  C07C279/18

    CPC分类号： C07C279/265

    摘要： A novel bis-biguanide compound suitable for use as a disinfectant has the following formula: ##STR1## where n is an integer from 2 to 10 inclusive. A pharmaceutically acceptable salt, particularly gluconate salt of the compound is also useful as a disinfectant. The bis-biguanide compound has germicidal activities comparable to those of widely used chlorhexidine with respect to width of antibacterial spectrum and is superior to chlorhexidine in immediate effectiveness. It exhibits excellent germicidal activities against Pyocyaneus bacilli, on which chlorhexidine has poor effect.

    摘要翻译： 适合用作消毒剂的新型双双胍化合物具有以下分子式：其中n为2至10的整数，包括端值。 化合物的药学上可接受的盐，特别是葡萄糖酸盐也可用作消毒剂。 双胍类化合物具有与广泛使用的氯己定相比具有抗菌谱宽度的杀菌活性，并且立即有效地优于氯己定。 它对抗疟原菌显示出优异的杀菌活性，氯己定对其效果不佳。