公开(公告)号：US5957130A

公开(公告)日：1999-09-28

申请号：US917184

申请日：1997-08-25

申请人： Erik Krahbichler ,  Fredrik Jalde

发明人： Erik Krahbichler ,  Fredrik Jalde

IPC分类号： A61M16/10 ,  A61M16/00 ,  A61M16/20 ,  A62B7/00

CPC分类号： A61M16/009 ,  A61M16/0075

摘要： A device for compensating for flow resistance in an expiratory section of a ventilator system has a bellows system whose increase in volume during expiration is regulated by a regulatory device and a control unit, so that expired gas fills the bellows system. The increase in volume is regulated according to values measured for pressure so virtually complete compensation for flow resistance is attained. Pressure is measured with a first pressure gauge located by the bellows system, and a second pressure gauge located by the patient. The device can be a separate apparatus which is connectable to a ventilator, or can be totally integrated into the ventilator.

摘要翻译： 用于补偿呼吸机系统的呼气部分中的流动阻力的装置具有波纹管系统，其在呼气期间的体积增加由调节装置和控制单元调节，使得呼出气体填充波纹管系统。 体积的增加根据对压力测量的值进行调节，从而实现对流阻的实际完全补偿。 用波纹管系统定位的第一压力表和由患者定位的第二压力表来测量压力。 该装置可以是可连接到呼吸机的单独设备，或者可以完全集成到呼吸机中。

公开(公告)号：US08485980B2

公开(公告)日：2013-07-16

申请号：US12239134

申请日：2008-09-26

申请人： Christer Sinderby ,  Jennifer Beck ,  Fredrik Jalde ,  Joachim Sallvin

发明人： Christer Sinderby ,  Jennifer Beck ,  Fredrik Jalde ,  Joachim Sallvin

IPC分类号： A61B5/08 ,  A61B5/042

CPC分类号： A61B5/08 ,  A61B5/0421 ,  A61B5/0488 ,  A61M16/00 ,  A61M16/024 ,  A61M2016/0021 ,  A61M2202/0208 ,  A61M2210/1014 ,  A61M2210/105 ,  A61M2230/04 ,  A61M2230/08 ,  A61M2230/60 ,  A61M2230/005

摘要： In a method and device for positioning a linear array of electrodes mounted on a distal end section of an elongated flexible member in a patient's respiratory airways at the level of the patient's diaphragm, a length of the elongated flexible member pre-determined to position the linear array of electrodes at the level of the patient's diaphragm is inserted through the patient's respiratory airways. Signals representative of an electrical activity of the patient's diaphragm (EAdi) are detected through the electrodes of the linear array, a presence or absence of ECG signal components is detected in the EAdi signals, and the position of the linear array of electrodes in the patient's respiratory airways is detected in response to the presence or absence of the ECG signal components in the EAdi signals. Also, lower esophageal sphincter activity may be detected in the EAdi signals, and the position of the linear array of electrodes in the patient's respiratory airways determined in response to the detected lower esophageal sphincter. Finally, an end-expiratory occlusion of the patient's respiratory airways may be performed to verify that the electrical activity of the diaphragm coincides with a negative deflection of the patient's respiratory airways pressure again in view of determining adequate positioning of the linear array of electrodes.

摘要翻译： 在用于定位安装在患者呼吸气道中的细长柔性构件的远端部分上的电极的线性阵列的方法和装置中，该患者的呼吸气道位于患者隔膜的水平面处，预定的细长柔性构件的长度定位成线性 患者隔膜水平面上的电极阵列插入病人的呼吸道。 通过线性阵列的电极检测代表患者隔膜（EADi）的电活动的信号，在EAdi信号中检测到ECG信号分量的存在或不存在，以及患者的电极线性阵列的位置 响应EADi信号中ECG信号分量的存在或不存在来检测呼吸气道。 此外，可以在EAdi信号中检测到较低的食管括约肌活动，并且响应于检测到的食管下括约肌确定患者呼吸气道中的电极线性阵列的位置。 最后，考虑到确定电极的线性阵列的适当定位，可以执行患者呼吸气道的呼气末阻塞以验证隔膜的电活动与患者的呼吸气道压力的负偏转重合。

公开(公告)号：US08280498B2

公开(公告)日：2012-10-02

申请号：US12615405

申请日：2009-11-10

申请人： Fredrik Jalde

发明人： Fredrik Jalde

IPC分类号： A61B5/04

CPC分类号： A61B5/061 ,  A61B5/0421 ,  A61B5/0452 ,  A61M16/024 ,  A61M16/0463 ,  A61M2205/502 ,  A61M2230/60 ,  A61M2230/005

摘要： A method of obtaining an indication of the position of an esophageal catheter inserted into a patient includes the steps of obtaining an electrical signal from the esophageal catheter, determining an ECG component of the electrical signal, determining the widths and/or rate of a number of periods in which the ECG component exceeds a threshold value, using the rate or widths of the periods to determine the presence of a P-wave in the ECG component, and concluding that the catheter is in a good position for obtaining a correct EMG signal if a P-wave is determined to be present. If not, the position may be corrected. The method may be performed by a control unit in a ventilator or a monitoring device.

摘要翻译： 获得插入患者的食管导管的位置的指示的方法包括以下步骤：从食管导管获得电信号，确定电信号的ECG分量，确定多个 使用周期的速率或宽度来确定ECG分量中的P波的存在的时间，其中ECG分量超过阈值的时间段，并且断定导管处于用于获得正确的EMG信号的良好位置，如果 确定存在P波。 如果没有，则可以更正该位置。 该方法可以由呼吸机或监视装置中的控制单元执行。

公开(公告)号：US20100180896A1

公开(公告)日：2010-07-22

申请号：US12597642

申请日：2007-04-27

申请人： Karin Blomquist ,  Fredrik Jalde

发明人： Karin Blomquist ,  Fredrik Jalde

IPC分类号： A61M16/00

CPC分类号： A61B5/04884 ,  A61B5/06 ,  A61B5/065 ,  A61M16/0051 ,  A61M16/024 ,  A61M16/12 ,  A61M2205/3331 ,  A61M2205/502 ,  A61M2205/584 ,  A61M2210/1014 ,  A61M2210/105 ,  A61M2230/08 ,  A61M2230/60 ,  A61M2230/005

摘要： A control unit for controlling a ventilator that provides EMG controlled ventilation to a patient receives EMG signals from an esophageal catheter inserted into the patient and selects, dependent on the EMG signal, at least one signal for controlling the ventilator. A user interface unit operates by the control unit indicates the position of the catheter relative to the patient's diaphragm based on the selected signal. The position information may be presented in relation to signal curves representing the catheter signal or as an elongate vertical shape representing the catheter, the display unit being operated to indicate on the elongate vertical shape the position of the diaphragm.

摘要翻译： 用于控制向患者提供EMG控制的通气的呼吸机的控制单元从插入患者的食管导管接收EMG信号，并根据EMG信号选择用于控制呼吸机的至少一个信号。 控制单元操作的用户接口单元基于所选择的信号指示导管相对于患者隔膜的位置。 位置信息可以关于代表导管信号的信号曲线或作为表示导管的细长垂直形状来呈现，显示单元被操作以在细长的垂直形状上指示隔膜的位置。

公开(公告)号：US20090137911A1

公开(公告)日：2009-05-28

申请号：US12239134

申请日：2008-09-26

申请人： Christer Sinderby ,  Jennifer Beck ,  Fredrik Jalde ,  Joachim Sallvin

发明人： Christer Sinderby ,  Jennifer Beck ,  Fredrik Jalde ,  Joachim Sallvin

IPC分类号： A61B18/00 ,  A61B5/02

CPC分类号： A61B5/08 ,  A61B5/0421 ,  A61B5/0488 ,  A61M16/00 ,  A61M16/024 ,  A61M2016/0021 ,  A61M2202/0208 ,  A61M2210/1014 ,  A61M2210/105 ,  A61M2230/04 ,  A61M2230/08 ,  A61M2230/60 ,  A61M2230/005

摘要： In a method and device for positioning a linear array of electrodes mounted on a distal end section of an elongated flexible member in a patient's respiratory airways at the level of the patient's diaphragm, a length of the elongated flexible member pre-determined to position the linear array of electrodes at the level of the patient's diaphragm is inserted through the patient's respiratory airways. Signals representative of an electrical activity of the patient's diaphragm (EAdi) are detected through the electrodes of the linear array, a presence or absence of ECG signal components is detected in the EAdi signals, and the position of the linear array of electrodes in the patient's respiratory airways is detected in response to the presence or absence of the ECG signal components in the EAdi signals. Also, lower esophageal sphincter activity may be detected in the EAdi signals, and the position of the linear array of electrodes in the patient's respiratory airways determined in response to the detected lower esophageal sphincter. Finally, an end-expiratory occlusion of the patient's respiratory airways may be performed to verify that the electrical activity of the diaphragm coincides with a negative deflection of the patient's respiratory airways pressure again in view of determining adequate positioning of the linear array of electrodes.

摘要翻译： 在用于定位安装在患者呼吸气道中的细长柔性构件的远端部分上的电极的线性阵列的方法和装置中，该患者的呼吸气道位于患者隔膜的水平面处，预定的细长柔性构件的长度定位成线性 患者隔膜水平面上的电极阵列插入病人的呼吸道。 通过线性阵列的电极检测代表患者隔膜（EADi）的电活动的信号，在EAdi信号中检测到ECG信号分量的存在或不存在，以及患者的电极线性阵列的位置 响应EADi信号中ECG信号分量的存在或不存在来检测呼吸气道。 此外，可以在EAdi信号中检测到较低的食管括约肌活动，并且响应于检测到的食管下括约肌确定患者呼吸气道中的电极线性阵列的位置。 最后，考虑到确定电极的线性阵列的适当定位，可以执行患者呼吸气道的呼气末阻塞以验证隔膜的电活动与患者的呼吸气道压力的负偏转重合。

公开(公告)号：US06739336B1

公开(公告)日：2004-05-25

申请号：US09666386

申请日：2000-09-20

申请人： Fredrik Jalde ,  Anders Steiner

发明人： Fredrik Jalde ,  Anders Steiner

IPC分类号： A61M1600

CPC分类号： A61M16/202 ,  A61M16/026 ,  A61M2016/0039 ,  A61M2016/0042

摘要： A feedback controller for regulating respiratory gas in a mechanical breathing aid system has a comparator means for periodically generating, in a current breathing cycle, an error signal representing the difference between a value of a gas parameter measured for gas within the system and a target value of the gas parameter, and a control signal generator for processing the error signal in accordance with a control function to generate a control signal usable in the regulation of the respiratory gas. The controller has a variable value integral gain stage which provides an input to an integrator element. An adaption unit determines, for the current breathing cycle an extreme value of the periodically generated error signal and varies the value of the integral gain used in the integral gain stage for a next breathing cycle dependent on a rate of change of the value of the extreme error signal with value of the integral gain.

摘要翻译： 用于在机械呼吸辅助系统中调节呼吸气体的反馈控制器具有比较器装置，用于在当前呼吸周期中周期性地产生一个误差信号，该误差信号表示对系统内的气体测量的气体参数的值与目标值之间的差值 的气体参数，以及控制信号发生器，用于根据控制功能处理误差信号，以产生可用于调节呼吸气体的控制信号。 控制器具有可变值积分增益级，其向积分器元件提供输入。 适应单元为当前呼吸周期确定周期性产生的误差信号的极值，并根据极端值的变化率来改变在下一个呼吸周期中在积分增益级中使用的积分增益的值 具有积分增益值的误差信号。

公开(公告)号：US06564798B1

公开(公告)日：2003-05-20

申请号：US09616280

申请日：2000-07-14

申请人： Fredrik Jalde

发明人： Fredrik Jalde

IPC分类号： A62B962

CPC分类号： A61M16/20 ,  A61M16/205 ,  A61M2016/0039

摘要： In a method for controlling an expiratory valve in a ventilator during expiration, including a stage in which the expiratory valve is opened almost completely for a first interval. Opening the expiratory valve almost completely results in a reduction in expiratory resistance. Thus in the first interval of flow or pressure in the expiratory part of the ventilator, a determination is made when the flow or pressure in the expiratory part meets a condition. A second interval is started when the flow in the expiratory part meets the condition and the expiratory valve is regulated during the second interval in order to attain a pre-set end pressure in the expiratory section.

摘要翻译： 一种用于在呼气期间控制通气机中的呼气阀的方法，包括在第一间隔内几乎完全打开呼气阀的阶段。 打开呼气阀几乎完全导致呼气阻力降低。 因此，在呼吸机呼气部分的流动或压力的第一间隔中，当呼气部分的流量或压力达到条件时，进行判定。 当呼气部分的流量满足条件时，开始第二间隔，并且在第二间隔期间调节呼气阀以达到呼气部分中的预设终止压力。