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公开(公告)号:US20120178733A1
公开(公告)日:2012-07-12
申请号:US13213927
申请日:2011-08-19
申请人: Bing-Yan Zhu , Shawn M. Bauer , Zhaozhong J. Jia , Gary D. Probst , Yanchen Zhang , Robert M. Scarborough
发明人: Bing-Yan Zhu , Shawn M. Bauer , Zhaozhong J. Jia , Gary D. Probst , Yanchen Zhang , Robert M. Scarborough
IPC分类号: A61K31/422 , C07D413/14 , A61K31/454 , A61K31/5377 , A61K31/55 , A61K31/4545 , A61K31/4439 , A61K31/496 , A61K31/506 , C07D417/14 , A61K31/541 , A61K31/553 , A61K31/551 , C07D409/14 , C07D409/12 , A61K31/4192 , C07D417/12 , A61K31/427 , A61K31/4178 , A61K31/4709 , A61P9/00 , A61P9/10 , A01N1/02 , A61P7/02 , C07D413/12
CPC分类号: C07D413/14 , C07D333/38 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
摘要翻译: 本发明涉及由式I表示的化合物及其作为因子Xa抑制剂的药学上可接受的盐,溶剂合物,水合物和前药。 本发明还涉及用于制备这种化合物的中间体,含有这些化合物的药物组合物,预防或治疗多种不想要的血栓形成特征的病症的方法以及抑制血液样品凝固的方法。
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公开(公告)号:US20060100193A1
公开(公告)日:2006-05-11
申请号:US11158274
申请日:2005-06-20
申请人: Bing-Yan Zhu , Shawn Bauer , Zhaozhong Jia , Gary Probst , Yanchen Zhang , Robert Scarborough
发明人: Bing-Yan Zhu , Shawn Bauer , Zhaozhong Jia , Gary Probst , Yanchen Zhang , Robert Scarborough
IPC分类号: A61K31/5377 , A61K31/506 , A61K31/496 , A61K31/453 , A61K31/4745 , A61K31/422 , A61K31/397 , A61K31/381 , C07D413/02 , C07D409/02
CPC分类号: C07D413/14 , C07D333/38 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
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公开(公告)号:USD839759S1
公开(公告)日:2019-02-05
申请号:US29600899
申请日:2017-04-17
申请人: Yanchen Zhang , Meng Zhang
设计人: Yanchen Zhang , Meng Zhang
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公开(公告)号:USD764324S1
公开(公告)日:2016-08-23
申请号:US29528714
申请日:2015-05-31
申请人: Yanchen Zhang , Meng Zhang
设计人: Yanchen Zhang , Meng Zhang
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公开(公告)号:USD764322S1
公开(公告)日:2016-08-23
申请号:US29528715
申请日:2015-05-31
申请人: Yanchen Zhang , Meng Zhang
设计人: Yanchen Zhang , Meng Zhang
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公开(公告)号:USD717186S1
公开(公告)日:2014-11-11
申请号:US29459478
申请日:2013-06-29
申请人: Yanchen Zhang , Meng Zhang
设计人: Yanchen Zhang , Meng Zhang
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公开(公告)号:USD697440S1
公开(公告)日:2014-01-14
申请号:US29447156
申请日:2013-03-01
申请人: Yanchen Zhang , Meng Zhang
设计人: Yanchen Zhang , Meng Zhang
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公开(公告)号:US08461134B2
公开(公告)日:2013-06-11
申请号:US12944690
申请日:2010-11-11
申请人: Vincent S. Hernandez , Xianfeng Li , Suoming Zhang , Tsutomu Akama , Yanchen Zhang , Yang Liu , Jacob J. Plattner , Michael Richard Kevin Alley , Yasheen Zhou , James A. Nieman
发明人: Vincent S. Hernandez , Xianfeng Li , Suoming Zhang , Tsutomu Akama , Yanchen Zhang , Yang Liu , Jacob J. Plattner , Michael Richard Kevin Alley , Yasheen Zhou , James A. Nieman
CPC分类号: C07F5/025
摘要: This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.
摘要翻译: 本发明涉及6-取代的苯并恶唑化合物及其用于治疗细菌感染的用途。
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公开(公告)号:USD678086S1
公开(公告)日:2013-03-19
申请号:US29407907
申请日:2011-12-22
申请人: Meng Zhang , Yanchen Zhang
设计人: Meng Zhang , Yanchen Zhang
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公开(公告)号:US08153670B2
公开(公告)日:2012-04-10
申请号:US12348879
申请日:2009-01-05
申请人: Bing-Yan Zhu , Shawn M. Bauer , Zhaozhong J. Jia , Gary D. Probst , Yanchen Zhang , Robert M. Scarborough
发明人: Bing-Yan Zhu , Shawn M. Bauer , Zhaozhong J. Jia , Gary D. Probst , Yanchen Zhang , Robert M. Scarborough
IPC分类号: A61K31/415 , A61K31/4164 , A61K31/4192 , C07D249/04 , C07D233/66 , C07D207/34
CPC分类号: C07D413/14 , C07D333/38 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要: The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
摘要翻译: 本发明涉及由式I表示的化合物及其作为因子Xa抑制剂的药学上可接受的盐,溶剂合物,水合物和前药。 本发明还涉及用于制备这种化合物的中间体,含有这些化合物的药物组合物,预防或治疗多种不想要的血栓形成特征的病症的方法以及抑制血液样品凝固的方法。
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