公开(公告)号：US10093622B2

公开(公告)日：2018-10-09

申请号：US15562518

申请日：2015-06-04

Applicant: ANTHEA AROMATICS PRIVATE LIMITED

Inventor： Manoj Kumar Mohapatra ,  Ramamohanrao Bendapudi ,  Paul Vincent Menacherry ,  Vincent Paul

IPC: C07D201/04 ,  C07D201/06 ,  C01B21/14 ,  C01G9/02 ,  C07D201/16 ,  C07D227/087 ,  B01D3/36

Abstract: Disclosed herein is an efficient, economical, industrially advantageous, straight-through process for the preparation of cyclic amides, also referred as lactams, in substantially pure form and high yield, from the corresponding cyclic ketones and a hydroxylammonium salt, using a combination of amphoteric metal oxide or amphoteric masked metal oxide and a base.

公开(公告)号：US08962826B2

公开(公告)日：2015-02-24

申请号：US14141916

申请日：2013-12-27

Applicant: Ube Industries, Ltd.

Inventor： Junichi Kugimoto ,  Joji Kawai ,  Kazuo Yamato ,  Masahide Okada ,  Tsunemi Sugimoto ,  Hiroshi Matsumoto

IPC: C07D225/02 ,  C07D201/04 ,  C07D201/06

CPC classification number: C07D201/06 ,  C07D201/04 ,  C07D225/02

Abstract: A method for producing a high purity, high quality amide compound, particularly a lactam. An amount of each of a halide, an aldehyde compound, an alcohol compound and a nitrile compound contained in a solution recycled into an oxime-forming step is controlled to an amount of 0.4 mol% or less based on the ketone as a starting material. One or more of a ketone, an oxime and an amide compound are purified by hydrogenation and/or crystallization for eliminating impurities containing a double bond. A content of impurities having a cyclic bridge structure is controlled using a cycloalkanone purified by recrystallization.

Abstract translation: 一种生产高纯度，优质酰胺化合物，特别是内酰胺的方法。 以循环到肟形成步骤的溶液中所含的卤化物，醛化合物，醇化合物和腈化合物中的每一种的量基于作为起始原料的酮被控制为0.4摩尔％以下的量。 通过氢化和/或结晶来纯化酮，肟和酰胺化合物中的一种或多种，​​以消除含有双键的杂质。 使用通过重结晶纯化的环烷酮控制具有环状桥结构的杂质含量。

公开(公告)号：US20140114062A1

公开(公告)日：2014-04-24

申请号：US14141916

申请日：2013-12-27

Applicant: Ube Industries, Ltd.

Inventor： Junichi Kugimoto ,  Joji Kawai ,  Kazuo Yamato ,  Masahide Okada ,  Tsunemi Sugimoto ,  Hiroshi Matsumoto

IPC: C07D201/06 ,  C07D225/02

CPC classification number: C07D201/06 ,  C07D201/04 ,  C07D225/02

Abstract: A method for producing a high purity, high quality amide compound, particularly a lactam. An amount of each of a halide, an aldehyde compound, an alcohol compound and a nitrile compound contained in a solution recycled into an oxime-forming step is controlled to an amount of 0.4 mol % or less based on the ketone as a starting material. One or more of a ketone, an oxime and an amide compound are purified by hydrogenation and/or crystallization for eliminating impurities containing a double bond. A content of impurities having a cyclic bridge structure is controlled using a cycloalkanone purified by recrystallization.

Abstract translation: 一种生产高纯度，优质酰胺化合物，特别是内酰胺的方法。 以循环到肟形成步骤的溶液中所含的卤化物，醛化合物，醇化合物和腈化合物中的每一种的量基于作为起始原料的酮被控制为0.4摩尔％以下的量。 通过氢化和/或结晶来纯化酮，肟和酰胺化合物中的一种或多种，​​以消除含有双键的杂质。 使用通过重结晶纯化的环烷酮控制具有环状桥结构的杂质含量。

公开(公告)号：US5599987A

公开(公告)日：1997-02-04

申请号：US414677

申请日：1995-03-31

Applicant: Guy L. Crocco ,  John C. Jubin, Jr. ,  John G. Zajacek

Inventor： Guy L. Crocco ,  John C. Jubin, Jr. ,  John G. Zajacek

IPC: C07C249/04 ,  C07D201/02 ,  C07D201/04 ,  C07D201/06

CPC classification number: C07C249/04 ,  Y02P20/125

Abstract: An integrated process for producing cyclohexanone oxime, a caprolactam precursor, is provided wherein isopropanol is utilized to generate the hydrogen peroxide oxidizing agent. The acetone produced as a co-product is recycled back to the secondary alcohol by hydrogenation. Ammoximation of cyclohexanone is performed in the presence of water and an alcohol other than isopropanol such as methanol or t-butyl alcohol.

Abstract translation: 提供了一种用于生产环己酮肟，己内酰胺前体的综合方法，其中使用异丙醇生成过氧化氢氧化剂。 作为副产物生产的丙酮通过氢化再循环回到仲醇中。 在水和除异丙醇之外的醇（如甲醇或叔丁醇）的存在下进行环己酮的接近。

公开(公告)号：US5451701A

公开(公告)日：1995-09-19

申请号：US266820

申请日：1994-06-27

Applicant: John G. Zajacek ,  John C. Jubin ,  Guy L. Crocco

Inventor： John G. Zajacek ,  John C. Jubin ,  Guy L. Crocco

IPC: C07C249/04 ,  C07C251/44 ,  C07D201/02 ,  C07D201/04 ,  C07D201/06

CPC classification number: C07C249/04 ,  C07C251/44 ,  Y02P20/125

Abstract: An integrated process for producing cyclohexanone oxime, a caprolactam precursor, is provided wherein a secondary alcohol is utilized to generate the hydrogen peroxide oxidizing agent and as a reaction medium for ammoximation. The ketone produced as a co-product is recycled back to the secondary alcohol by hydrogenation.

Abstract translation: 提供了一种用于生产环己酮肟，己内酰胺前体的综合方法，其中使用仲醇产生过氧化氢氧化剂和作为氨肟化反应的反应介质。 作为副产物生产的酮通过氢化再循环回到仲醇中。

公开(公告)号：US5264571A

公开(公告)日：1993-11-23

申请号：US954731

申请日：1992-09-30

Applicant: Hugo Fuchs ,  Gerald Neubauer ,  Josef Ritz

Inventor： Hugo Fuchs ,  Gerald Neubauer ,  Josef Ritz

IPC: C07D201/04 ,  C07D201/06 ,  C07D223/10 ,  C07D201/16

CPC classification number: C07D201/04 ,  C07D201/06

Abstract: A process for preparing caprolactam by Beckmann rearrangement of cyclohexanone oxime with oleum at from 85.degree. to 125.degree. C. in a plurality of rearrangement stages arranged in series entails returning a portion of the reaction mixture leaving the last rearrangement stage to at least one of the preceding rearrangement stages.

Abstract translation: 通过贝克曼重整环己酮肟与发烟硫酸在85℃至125℃下重排排列的多个重排阶段制备己内酰胺的方法需要将离开最后一个重排阶段的一部分反应混合物返回至 以前的重排阶段。