公开(公告)号：US4390535A

公开(公告)日：1983-06-28

申请号：US240666

申请日：1981-03-05

申请人： Hirotada Yamada ,  Kiyokazu Jimpo ,  Takao Okuda ,  Hiroshi Noguchi ,  Hisao Tobiki

发明人： Hirotada Yamada ,  Kiyokazu Jimpo ,  Takao Okuda ,  Hiroshi Noguchi ,  Hisao Tobiki

IPC分类号： A61K31/545 ,  C07D501/36 ,  C07D501/56

CPC分类号： C07D501/36 ,  C07D501/46

摘要： Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or a (C.sub.1 -C.sub.4) alkyl group, X is a straight or branched chain C.sub.1 -C.sub.4 alkylene group and R.sub.2 is a carboxyl group or a sulfo group; and the pharmaceutically acceptable salts thereof exhibit strong inhibitory activities against a wide variety of Gram-positive and Gram-negative bacteria including Psendomonas aeruginosa, indolepositive Proteus and Enterobacter aerogenes, and also have an increased and prolonged serum level in a living body. The compounds are therefore useful as antibacterial agents for the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria.

摘要翻译： 其中R 1为氢或（C 1 -C 4）烷基，X为直链或支链C 1 -C 4亚烷基，R 2为羧基或磺基; 其药学上可接受的盐显示出对各种革兰氏阳性和革兰氏阴性细菌（包括铜绿假单胞菌，吲哚阳性变形杆菌和产气肠杆菌）的抑制活性，并且在活体中也具有增加和延长的血清水平。 因此，这些化合物可用作治疗由革兰氏阳性和革兰氏阴性菌引起的感染性疾病的抗菌剂。

公开(公告)号：US4384055A

公开(公告)日：1983-05-17

申请号：US302849

申请日：1981-09-16

申请人： Takao Okuda ,  Nobuhide Hada

发明人： Takao Okuda ,  Nobuhide Hada

IPC分类号： C08L27/00 ,  C08K3/02 ,  C08K3/04 ,  C08L1/00 ,  C08L27/06 ,  C08L33/00 ,  C08L33/02

CPC分类号： C08K3/04 ,  C08L27/06 ,  C08L2205/02

摘要： A hard vinyl chloride resin composition for information signal recording media, said composition consisting essentially of(A) 100 parts by weight of a copolymer having a specific viscosity of 0.16 to 0.31 and composed of 75 to 99% by weight of vinyl chloride, 1 to 10% by weight of ethylene and 0 to 15% by weight of another monomer copolymerizable with said monomers, and/or a polymer mixture having a specific viscosity of 0.16 to 0.31 and composed of at least two polymers selected so that the proportions of monomer components are the same as above, and(B) 15 to 30 parts by weight of carbon black having an oil absorption of 300 to 400 ml/100g and a surface area of at least 900 m.sup.2 /g.

摘要翻译： 一种用于信息信号记录介质的硬质氯乙烯树脂组合物，所述组合物基本上由（A）100重量份的比粘度为0.16至0.31的共聚物和75至99重量％的氯乙烯组成，1至 10重量％的乙烯和0至15重量％的可与所述单体共聚的另一单体，和/或比粘度为0.16至0.31并由至少两种聚合物组成的聚合物混合物，其选择为使得单体成分 与上述相同，（B）15〜30重量份的吸油量为300〜400ml / 100g，表面积为900m 2 / g以上的炭黑。