公开(公告)号：US20170190674A1

公开(公告)日：2017-07-06

申请号：US15316468

申请日：2015-06-05

申请人： Arizona Board of Regents on behalf of Arizona State University

发明人： Jeffrey LaBelle ,  Trevor Saxman ,  Brittney Haselwood

IPC分类号： C07D245/04 ,  G01N33/66

CPC分类号： C07D245/04 ,  G01N33/66

摘要： Synthesis of novel and unique PAMAM (poly-amidoamine) polymers. PAMAM polymers can be grown by systematic alternation between ethylenediamine (EDA) and methacrylate. By taking advantage of the alternating terminal ends, successive generations G1 and G0.5 were combined under acidic conditions with Pluronic P123 as a liquid-crystal template. The resulting polymer was imaged with TEM and the product was circular and amorphous of no characteristic size ranging between about 5 nm to about 600 nm, with remarkable electrochemical activity unseen in any of the generations of PAMAM. Applications of this electroactive poly-amidoamine organic polymer include use as a new electron transfer reagent for amperometric biosensors.