公开(公告)号：US11229777B2

公开(公告)日：2022-01-25

申请号：US17389894

申请日：2021-07-30

Applicant: Cagent Vascular, Inc.

Inventor： Peter Schneider ,  Robert Giasolli

IPC: A61M25/10 ,  A61M37/00 ,  A61B17/20 ,  A61B17/22 ,  A61B17/00 ,  A61B17/3207 ,  A61M25/00

Abstract: A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.

公开(公告)号：US20210353918A1

公开(公告)日：2021-11-18

申请号：US17390122

申请日：2021-07-30

Applicant: Cagent Vascular, Inc.

Inventor： Robert M. Giasolli ,  Peter Schneider ,  Peter Johansson ,  Carol Burns

IPC: A61M25/10 ,  A61M25/00

Abstract: Systems and methods can involve wedge dissectors attached to strips in turn attached to medical balloons, for forming serrations within vascular wall tissue for angioplasty as well as drug delivery.

公开(公告)号：US20210353917A1

公开(公告)日：2021-11-18

申请号：US17390091

申请日：2021-07-30

Applicant: Cagent Vascular, Inc.

Inventor： Peter Schneider ,  Robert Giasolli

IPC: A61M25/10 ,  A61B17/20 ,  A61B17/3207

Abstract: A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.