公开(公告)号：US20210077259A1

公开(公告)日：2021-03-18

申请号：US17105373

申请日：2020-11-25

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin

IPC: A61F2/24 ,  A61F2/02

Abstract: A method and device for anchoring a prosthetic heart valve or annuloplasty ring to a valve annulus in a heart and a method of implanting same is disclosed. The device can include a prosthetic valve or annuloplasty ring with one or more anchors configured to be threaded or otherwise passed underneath a native leaflet and/or subvalvular tissue to secure the device at the native annulus.

公开(公告)号：US20210022862A1

公开(公告)日：2021-01-28

申请号：US17067598

申请日：2020-10-09

Applicant: Edwards Lifesciences Corporation

Inventor： Ankita Bordoloi Gurunath ,  Derrick Johnson ,  Brian S. Conklin ,  Myron Howanec, JR.

IPC: A61F2/24

Abstract: A prosthetic heart valve holder system includes a prosthetic heart valve having a base at an inflow end, a plurality of commissure posts extending from the base toward an outflow end, and valve leaflets secured to the commissure posts to permit flow through the heart valve. A deflector is provided at the outflow end having a central hub and a plurality of arms extending from the central hub secured to and covering the tips of respective commissure posts. A valve support body is secured to the base and a post connects the valve support body to the hub of the deflector. The plurality of arms are sufficiently collapsible such that, in a first position, free ends of the arms are located axially between the hub and the valve support body to prevent suture looping during an implant procedure, and in a second position, the hub is located axially between the free ends of the arms and the valve support body to permit removal of the deflector from the outflow side of the valve, through the valve leaflets, to the inflow side of the valve.

公开(公告)号：USD908874S1

公开(公告)日：2021-01-26

申请号：US29656209

申请日：2018-07-11

Applicant: Edwards Lifesciences Corporation

Designer： Brian S. Conklin

公开(公告)号：US10751174B2

公开(公告)日：2020-08-25

申请号：US16141604

申请日：2018-09-25

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Da-Yu Chang

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.

公开(公告)号：US10736741B2

公开(公告)日：2020-08-11

申请号：US15864992

申请日：2018-01-08

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.

公开(公告)号：US10702383B2

公开(公告)日：2020-07-07

申请号：US15990332

申请日：2018-05-25

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Brian S. Conklin ,  Paul A. Schmidt ,  Grace M. Kim ,  James A. Davidson ,  Hoa T. Tran ,  Kristy L. Tam

IPC: A61F2/24

Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.

公开(公告)号：US10695170B2

公开(公告)日：2020-06-30

申请号：US15199743

申请日：2016-06-30

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Qinggang Zeng

IPC: A61F2/24

Abstract: A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.

公开(公告)号：US20200155309A1

公开(公告)日：2020-05-21

申请号：US16773802

申请日：2020-01-27

Applicant: Edwards Lifesciences Corporation

Inventor： Visith Chung ,  Da-Yu Chang ,  Brian S. Conklin ,  Grace Myong Kim ,  Louis A. Campbell ,  Donald E. Bobo, JR. ,  Myron Howanec, JR. ,  David S. Lin ,  Peng Norasing ,  Francis M. Tran ,  Mark Van Nest ,  Thomas Chien ,  Harvey H. Chen ,  Isidro L. Guerrero ,  Derrick Johnson ,  Paul A. Schmidt

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

公开(公告)号：US20200060821A1

公开(公告)日：2020-02-27

申请号：US16673487

申请日：2019-11-04

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Michael C. Murad

IPC: A61F2/24

Abstract: A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.

公开(公告)号：US20200060815A1

公开(公告)日：2020-02-27

申请号：US16666331

申请日：2019-10-28

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace Myong Kim

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate valve-in-valve (ViV) procedures. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates ViV procedures.