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公开(公告)号:US20200369705A1
公开(公告)日:2020-11-26
申请号:US16876843
申请日:2020-05-18
Applicant: H. Lundbeck A/S
Inventor: Martin Juhl , Lisbet Kværnø , Mikkel Fog Jacobsen
IPC: C07H15/26
Abstract: The present invention relates to a process for manufacturing (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]guinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid with the formula (Id) below and pharmaceutically acceptable salts thereof The compound of formula (Id) is a prodrug of a catecholamine for use in treatment of neurodegenerative diseases and disorders such as Parkinson's Disease.The invention also relates to a new intermediate of said process.