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46 条记录 (耗时 0.041 秒)

    Methods of treating p38 kinase-mediated disorders with pyrido[2,3-d]pyrimidin-7-one compounds
    33.
    发明授权
    Methods of treating p38 kinase-mediated disorders with pyrido[2,3-d]pyrimidin-7-one compounds 失效
    用吡啶并[2,3-d]嘧啶-7-酮化合物治疗p38激酶介导的病症的方法

    公开(公告)号：US06861423B2

    公开(公告)日：2005-03-01

    申请号：US10230723

    申请日：2002-08-29

    申请人： Jian Jeffrey Chen ,  James Patrick Dunn ,  David Michael Goldstein ,  Julie Anne Lim

    发明人： Jian Jeffrey Chen ,  James Patrick Dunn ,  David Michael Goldstein ,  Julie Anne Lim

    IPC分类号： C07D239/46 ,  C07D471/04 ,  A61K31/535 ,  A61K31/52

    CPC分类号： C07D239/47 ,  C07D471/04

    摘要： Disorders mediated by p38 kinase inhibitors are treated with compounds of the formula: or salts thereof, wherein: R1 is hydrogen or alkyl; R2 is substituted cycloalkyl, heterosubstituted cycloalkyl, helcroalkylsubstituted cycloalkyl, heterosubstituted cycloalkyl-alkly, heterocyclyl, heterocyclyl spiro cycloalkyl, aralkoxy, alkoxy, -alkylene-S(O)n-alkyl (where is 1 or 2) or —SO2Ar2; R3 is hydrogen, amino, monoalkylamino, dialkylamino, acylamino, —NR8—C(═O)—Rb (where Ra is hydrogen or alkyl and Rh is heterocyclyl or heteroalkyl), alkyl, cycloalkyl, phthalimidoalkyl, aryl, aralkyl, haloalkyl, heteroalkyl, cyanoalkyl, -alkylene-C(O) R (where R is hydrogen, alkyl, hydroxy, alkoxy, amino, monoalkylamino or dialkylamino) or acyl; and each of Ar1 and Ar2 is independently aryl.

    摘要翻译： 由p38激酶抑制剂介导的疾病用下式化合物或其盐处理，其中：R 1是氢或烷基; R 2是取代的环烷基，杂取代的环烷基，环烷基取代的环烷基，杂取代的环烷基 - 烷基，杂环基， 杂环基螺环烷基，芳烷氧基，烷氧基， - 亚烷基-S（O）n-烷基（其中为1或2）或-SO 2 Ar 2; R 3为氢，氨基，单烷基氨基，二烷基氨基，酰氨基， （其中R 1为氢或烷基且R h为杂环基或杂烷基），烷基，环烷基，苯二甲酰亚氨基烷基，芳基，芳烷基，卤代烷基，杂烷基，氰基烷基， - 亚烷基-C（O）R（其中R是氢，烷基，羟基，烷氧基，氨基，单烷基氨基或二烷基氨基）或酰基; Ar 1和Ar 2的每一个独立地是芳基。

    System for providing calling party selection of destination when multiple telephones share the same telephone number
    35.
    发明授权
    System for providing calling party selection of destination when multiple telephones share the same telephone number 失效
    用于当多个电话共享相同电话号码时提供呼叫方选择目的地的系统

    公开(公告)号：US06643365B1

    公开(公告)日：2003-11-04

    申请号：US09547502

    申请日：2000-04-12

    申请人： James Patrick Dunn ,  Joan Marie Richied

    发明人： James Patrick Dunn ,  Joan Marie Richied

    IPC分类号： H04M342

    CPC分类号： H04Q3/0029

    摘要： A telecommunications system that recognizes “post-fix” codes after directory numbers are dialed. Such post-fix codes provide the calling party with the ability to invoke features or functions before the call is routed. By use of a post-fix code (for example, *X or *XX) the caller may, for example, control routing of a telephone call.

    摘要翻译： 拨打电话号码后识别“修复后”代码的电信系统。 这样的修复后代码为主叫方提供在呼叫路由之前调用特征或功能的能力。 通过使用固定后码（例如，* X或* XX），呼叫者可以例如控制电话呼叫的路由。

    Optimum routing of calls over the public switched telephone network and the internet
    36.
    发明授权
    Optimum routing of calls over the public switched telephone network and the internet 失效
    通过公共交换电话网络和互联网的呼叫的最佳路由

    公开(公告)号：US06324280B2

    公开(公告)日：2001-11-27

    申请号：US09072809

    申请日：1998-05-05

    申请人： James Patrick Dunn ,  Jack Kozik

    发明人： James Patrick Dunn ,  Jack Kozik

    IPC分类号： H04M700

    CPC分类号： H04L29/12018 ,  H04L12/6418 ,  H04L29/12009 ,  H04L61/10 ,  H04L2012/6443 ,  H04L2012/6472 ,  H04L2012/6475 ,  H04L2012/6486 ,  H04M7/0006 ,  H04M7/0009 ,  H04Q3/0025

    摘要： A method and apparatus for selectively establishing a connection via a telephone network, or via the Internet. A network access switch decides whether to use the telephone network or the Internet. If connections are established using the Internet, the establishment of connection is controlled using existing CCS7 interoffice signaling messages. Advantageously, this permits most of the switching control software to be retained and allows the access switches to interface with the present array of operations support systems.

    摘要翻译： 一种用于经由电话网络或经由互联网选择性地建立连接的方法和装置。 网络接入交换机决定是使用电话网还是Internet。 如果使用Internet建立连接，则使用现有的CCS7局间信令消息来控制建立连接。 有利地，这允许保留大多数开关控制软件，并允许接入交换机与当前的操作支持系统阵列接口。

    Call rejection interface for internet protocols
    40.
    发明授权
    Call rejection interface for internet protocols 失效
    互联网协议的呼叫拒绝接口

    公开(公告)号：US06701439B1

    公开(公告)日：2004-03-02

    申请号：US09343305

    申请日：1999-06-30

    申请人： James Patrick Dunn

    发明人： James Patrick Dunn

    IPC分类号： G06F1130

    CPC分类号： H04M15/00 ,  H04M15/06

    摘要： The present invention is directed to a method of call rejection provided for use in connection with a data network. It includes establishing a point-of-presence which serves as a termination point for receiving calls from clients. Received calls are then multiplexed into a tunnel as separate identifiable tunnel sessions. The tunnel sessions are received at a network server of the data network. Next, it is determined for each tunnel session if access to the data network is to be denied. If access is denied, then a call rejection message is returned to the point-of-presence via the tunnel. In a preferred embodiment, the call rejection message identifies the tunnel session which is denied access and a reason for denial such that at the point-of-presence appropriate action may be taken in response thereto. In the case of suspected intrusion by an unauthorized entity, this action involves a form of deterrent and/or surveillance. In the case of internet telephony, where the data network cannot successfully handle the call, the action involves rerouting the call via a crank back.

    摘要翻译： 本发明涉及提供用于与数据网络结合使用的呼叫拒绝方法。 它包括建立一个存在点，作为从客户端接收呼叫的终止点。 接收到的呼叫然后被复用到隧道中作为单独的可识别隧道会话。 在数据网络的网络服务器处接收隧道会话。 接下来，如果要拒绝对数据网络的访问，则确定每个隧道会话。 如果访问被拒绝，则呼叫拒绝消息通过隧道返回到存在点。 在优选实施例中，呼叫拒绝消息标识被拒绝访问的隧道会话和拒绝的原因，使得在可以存在的适当动作的位置可以响应于此而进行。 在怀疑被擅自实体入侵的情况下，这一行动涉及一种威慑和/或监视的形式。 在互联网电话的情况下，数据网络无法成功处理呼叫，该动作涉及通过曲柄回路重新路由呼叫。