Transdermal drug delivery devices containing O-Desmethyl Venlafaxine (ODV) or its salts
    32.
    发明申请
    Transdermal drug delivery devices containing O-Desmethyl Venlafaxine (ODV) or its salts 审中-公开
    含有O-去甲基文拉法辛(ODV)或其盐的透皮药物递送装置

    公开(公告)号:US20070053968A1

    公开(公告)日:2007-03-08

    申请号:US11515708

    申请日:2006-09-05

    IPC分类号: A61K9/70 A61K31/138

    CPC分类号: A61K9/7023 A61K31/138

    摘要: The present invention provides transdermal drug delivery devices (i.e., patches) comprising O-desmethylvenlafaxine (ODV), a selective serotonin and norepinephrine re-uptake inhibitor, or a pharmaceutically acceptable salt thereof, which, among other, offer the advantage of eliminating or reducing the adverse side effects associated with the oral administration of ODV. Also provided are methods of preparing and using these transdermal delivery systems for the treatment of depression, anxiety disorders, vasomotor symptoms and pain.

    摘要翻译: 本发明提供了包含O-去甲基文拉法辛(ODV),选择性5-羟色胺和去甲肾上腺素再摄取抑制剂或其药学上可接受的盐的透皮药物递送装置(即贴剂),其除了提供消除或减少 与ODV口服给药有关的副作用。 还提供了制备和使用这些透皮递送系统用于治疗抑郁症,焦虑症,血管舒缩症状和疼痛的方法。