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31.
公开(公告)号:US20080075746A1
公开(公告)日:2008-03-27
申请号:US11632686
申请日:2005-07-11
申请人: Stefan Muller , Thomas Ehlis , Jochen Giesinger , Gilbert Kreyer
发明人: Stefan Muller , Thomas Ehlis , Jochen Giesinger , Gilbert Kreyer
CPC分类号: A61Q17/04 , A61K8/02 , A61K9/107 , A61K2800/412
摘要: Disclosed is the use of an insoluble or sparingly soluble micronized substance class which is not a cosmetic UV absorber and which is dispersed in the oil- or water-phase of a cosmetic or dermatological composition for the enhancement of light protecting action of this cosmetic or dermatological composition comprising at least one cosmetic UV filter which is soluble in the water- or oil-phase. The cosmetic preparation according to the invention shows a remarkable increase in SPF.
摘要翻译: 公开了使用不是化妆品UV吸收剂并且分散在化妆品或皮肤病学组合物的油相或水相中的不溶性或微溶的微粉化物质类,以增强该化妆品或皮肤病学的光保护作用 组合物,其包含至少一种可溶于水相或油相的化妆品UV过滤器。 根据本发明的化妆品显示出SPF的显着增加。
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公开(公告)号:US20060052265A1
公开(公告)日:2006-03-09
申请号:US10531906
申请日:2003-10-21
申请人: Gunther Schlingloff , Torsten Wieprecht , Uwe Heinz , Albert Schneider , Marie-Josee Dubs , Frank Bachmann , Menno Hazenkamp , Thomas Ehlis , Cornelia Vincenzi , Josef Dannacher
发明人: Gunther Schlingloff , Torsten Wieprecht , Uwe Heinz , Albert Schneider , Marie-Josee Dubs , Frank Bachmann , Menno Hazenkamp , Thomas Ehlis , Cornelia Vincenzi , Josef Dannacher
CPC分类号: C07D401/14 , C11D3/168 , C11D3/3932
摘要: Use of metal complex compounds of formula (1) and/or (1′) [LnMemXp]zYq (1), [L′nMemXp]zYq (1′), wherein all substituents are as defined in the claims, as catalysts for oxidation reactions, and also novel metal complex compounds and novel ligands.
摘要翻译: 使用式(1)和/或(1')的金属配合物化合物[L L z> z z z z z (1),(1),[L',N,N,M, (1'),其中所有取代基如权利要求中所定义,作为氧化反应的催化剂,以及新型金属络合物和新配体。
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公开(公告)号:US20050175554A1
公开(公告)日:2005-08-11
申请号:US10511852
申请日:2003-04-14
申请人: Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
发明人: Barbara Wagner , Thomas Ehlis , Sebastien Mongiat , Kai Eichin
IPC分类号: A61K8/00 , A61K8/49 , A61K8/893 , A61K8/894 , A61K8/898 , A61K8/92 , A61K31/428 , A61P17/16 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q5/02 , A61Q17/04 , A61Q19/00 , C07D277/66 , A61K7/42 , C07D277/60
CPC分类号: A61K8/49 , A61K8/893 , A61K8/894 , A61Q17/04 , C07D277/66
摘要: The Use, as a UV filter, of a compound of formula (I), wherein R1 and R2 are each independently of the other hydrogen; unsubstituted or halo-, amino-, mono- or di-C1-C5alkylamino-, cyano- or C1-C5alkoxy-substituted C1-C22alkyl, C5-C10cycloalkyl, carboxy-C1-C22alkyl, carboxy-C6-C10aryl, C6-C10aryl, C6-C10aryl-C1-C5alkyl; carbamoyl; or sulfamoyl; or R1 and R2, together with the nitrogen atom linking them, form a 5- to 7-membered heterocyclic radical; and R3 is hydrogen; or C1-C22alkyl; and R4 is hydrogen; hydroxy; C1-C22alkyl; or C1-C22alkoxy; is described. The compounds of formula (I) are suitable especially as UV filters in cosmetic preparations.
摘要翻译: 用作UV过滤器的式(I)化合物,其中R 1和R 2各自独立于另一个氢; 未取代的或卤代,氨基 - ,单 - 或二-C 1 -C 5烷基氨基 - ,氰基 - 或C 1 -C 1 - C 5烷氧基取代的C 1 -C 22烷基,C 5 -C 10烷基,C 5 -C 20烷基, 环烷基,羧基-C 1 -C 22烷基,羧基-C 6 -C 10芳基,C 1 -C 6烷基, C 6 -C 10芳基,C 6 -C 10芳基-C 1 - C 5烷基; 氨基甲酰基; 或氨磺酰; 或R 1和R 2 2与连接它们的氮原子一起形成5-至7-元杂环基; 和R 3是氢; 或C 1 -C 22烷基; 并且R 4是氢; 羟基; C 1 -C 22烷基; C 1 -C 12烷基; 或C 1 -C 22烷氧基; 被描述。 式(I)的化合物特别适用于化妆品制剂中的UV过滤器。
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公开(公告)号:US6111103A
公开(公告)日:2000-08-29
申请号:US287029
申请日:1999-04-06
申请人: Thomas Ehlis , Elek Borsos , Helmut Luther , Bernd Herzog
发明人: Thomas Ehlis , Elek Borsos , Helmut Luther , Bernd Herzog
IPC分类号: A61K8/00 , A61K8/49 , A61Q17/04 , C07D251/22 , C07D251/26 , C07D405/12 , C08K5/3492 , C09K3/00 , C09K15/30
CPC分类号: C07D405/12 , A61K8/4966 , A61Q17/04 , C07D251/22
摘要: The invention relates to diresorcinyl-alkoxy- and -aryloxy-triazines of the formula ##STR1## in which R.sub.1 is C.sub.2 -C.sub.30 alkyl; C.sub.2 -C.sub.30 alkenyl; unsubstituted or C.sub.1 -C.sub.5 alkyl-mono- or polysubstituted C.sub.5 -C.sub.12 cycloalkyl, C.sub.1 -C.sub.5 alkoxy-C.sub.1 -C.sub.12 alkyl; amino-C.sub.1 -C.sub.12 alkyl; C.sub.1 -C.sub.5 monoalkylamino-C.sub.1 -C.sub.12 alkyl; C.sub.1 -C.sub.5 dialkylamino-C.sub.1 -C.sub.12 alkyl; a radical of the formula ##STR2## R.sub.2, R.sub.3 and R.sub.4, independently of one another, are hydrogen, hydroxyl, C.sub.1 -C.sub.30 alkyl, C.sub.1 -C.sub.30 alkenyl,R.sub.5 is hydrogen; or C.sub.1 -C.sub.5 alkyl;m.sub.1 is 0 or 1; andn.sub.1 is 1 to 5.The novel compounds are suitable as cosmetic UV-A absorbers.
摘要翻译: 本发明涉及下式的二缩水甘油基 - 烷氧基 - 和 - 芳氧基 - 三嗪,其中R 1是C 2 -C 30烷基; C2-C30烯基; 未取代的或C 1 -C 5烷基 - 单取代或多取代的C 5 -C 12环烷基,C 1 -C 5烷氧基-C 1 -C 12烷基; 氨基-C 1 -C 12烷基; C 1 -C 5单烷基氨基-C 1 -C 12烷基; C 1 -C 5二烷基氨基-C 1 -C 12烷基; 式R2,R3和R4彼此独立的基团是氢,羟基,C 1 -C 30烷基,C 1 -C 30烯基,R 5是氢; 或C 1 -C 5烷基; m1为0或1; n1为1〜5。新化合物适合作为化妆品UV-A吸收剂。
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公开(公告)号:US08444879B2
公开(公告)日:2013-05-21
申请号:US12227042
申请日:2007-05-02
申请人: Thomas Ehlis , Elek Borsos
发明人: Thomas Ehlis , Elek Borsos
IPC分类号: C07D251/52 , C07D251/70 , C07D403/12 , C07D403/14 , A61Q17/04 , A61K8/49
CPC分类号: C07D251/52 , C07D251/70
摘要: Disclosed are triazine derivatives of formula wherein X1 is a bivalent radical of formula A and A′ independently from each other are unsubstituted or substituted, straight-chain or branched C1-C12alkylene, which is optionally interrupted by C5-C12cycloalkylene, N, O or S; C5-C12cycloalkylene; biphenylene; C6-C10arylene; or C5-C10arylene-(C1-C12alkylene); R1 is a radical of formula R2 and R3 independently from each other are hydrogen; C1-C12alkyl; OR7; NR7R8; C6-C10aryl; X2 is O, or NH; W1 is C1-C20alkyl; or a group Sp-Sil; Sp is a straight-chain or branched saturated or single or multiple unsaturated C3-C12 hydrocarbon; Sil is a silane; an oligosiloxane; or a polysiloxane moiety; and R4, R5 R6, R7, R8 and R9 independently from each other are hydrogen; C1-C12alkyl; or C3-C12cycloalkyl.
摘要翻译: 公开了下式的三嗪衍生物其中X1是式A的二价基团,A'彼此独立地是未取代或取代的直链或支链C 1 -C 12亚烷基,其任选地被C 5 -C 12亚环烷基,N,O或S ; C5-C12环亚烷基; 联苯; C6-C10亚芳基 或C 5 -C 10亚芳基 - (C 1 -C 12亚烷基); R1是式R2和R3的基团彼此独立地是氢; C 1 -C 12烷基; OR7; NR7R8; C6-C10芳基; X2是O或NH; W1是C1-C20烷基; 或一组Sp-Sil; Sp是直链或支链饱和或单或多不饱和C 3 -C 12烃; 硅是硅烷; 低聚硅氧烷 或聚硅氧烷部分; R 4,R 5,R 6,R 7,R 8和R 9彼此独立地为氢; C 1 -C 12烷基; 或C 3 -C 12环烷基。
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公开(公告)号:US08404257B1
公开(公告)日:2013-03-26
申请号:US09830787
申请日:1999-10-21
IPC分类号: A61K8/00
CPC分类号: A61K8/347 , A61K8/37 , A61K8/42 , A61K8/46 , A61K8/466 , A61K8/4926 , A61K8/4966 , A61K8/4973 , A61K8/498 , A61K2800/522 , A61Q1/02 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q1/12 , A61Q5/02 , A61Q5/06 , A61Q9/02 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q17/04 , A61Q19/007 , A61Q19/10 , C11D3/0084 , C11D3/2034 , C11D3/28 , C11D3/30 , C11D3/32 , C11D3/349
摘要: A description is given of the use of phenolic antioxidants of formulae (1) and/or (2) and/or (3) for stabilizing body-care and household products.
摘要翻译: 给出了使用式(1)和/或(2)和/或(3)的酚类抗氧化剂来稳定身体护理和家用产品的描述。
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公开(公告)号:US20120128745A1
公开(公告)日:2012-05-24
申请号:US13322628
申请日:2010-05-19
申请人: Markus Hansch , Thomas Ehlis , Olof Wallquist , Barbara Wagner , Bernd Herzog , Jochen Giesinger
发明人: Markus Hansch , Thomas Ehlis , Olof Wallquist , Barbara Wagner , Bernd Herzog , Jochen Giesinger
摘要: Disclosed is the use of benzylidene malonates of formula (1) wherein R1 is methyl; ethyl; propyl; or n-butyl; if R1 is methyl, then R is tert. butyl; a radical of formula (1a) or a radical of formula (1b) wherein R2 and R3, independently from each other are hydrogen; or methyl; R4 is methyl; ethyl; or n-propyl; R5 and R6 independently from each other are hydrogen; or C1-C3alkyl; if R1 is ethyl; propyl; or n-butyl, then R is isopropyl; for the protection of human and animal hair and skin against UV radiation.
摘要翻译: 公开了使用式(1)的亚苄基丙二酸酯,其中R 1是甲基; 乙基; 丙基; 或正丁基; 如果R1是甲基,那么R是叔丁基。 丁基; 式(1a)的基团或式(1b)的基团,其中R2和R3彼此独立地为氢; 或甲基; R4是甲基; 乙基; 或正丙基; R5和R6彼此独立地是氢; 或C 1 -C 3烷基; 如果R1是乙基; 丙基; 或正丁基,那么R是异丙基; 用于保护人和动物的头发和皮肤免受紫外线辐射。
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公开(公告)号:US20120128611A1
公开(公告)日:2012-05-24
申请号:US13381965
申请日:2010-06-29
摘要: Disclosed is the use of a UV filter combination, comprising (a) a first UV filter selected from benzylidene malonates of formula (1), wherein R1 methyl; ethyl; propyl; or n-butyl; if R1 is methyl, then R is tert. butyl; formula (II); formula (III); a radical of formula (1a); or a radical of formula (1b); wherein R2 and R3, independently from each other are hydrogen; or methyl; R4 is methyl; ethyl; or n-propyl; R5 and R6 independently from each other are hydrogen; or C1-C3alkyl; if R1 is ethyl; propyl; or n-butyl, then R is isopropyl; and (b) a second UV filter selected from (b1) Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine; (b2) Butyl Methoxydibenzoylmethane; (b3)Diethylhexyl Butamido Triazone; (b4) Ethylhexyl Triazone; (b5) Diethylamino Hydroxy Benzoyl Hexyl Benzoate; (b6) Ethylhexyl Methoxycinnamate; (b7) Ethylhexyl Salicylate; (b8) Homosalate; (b9) Octocrylene; (b10) micronized Methylene Bis-Benzotriazolyl Tetramethylbutylphenol; (b11) Phenylbenzimidazole Sulfonic Acid; (b12) Titanium Dioxide; (b13) micronized Tris-Biphenyl Triazine; and (b14) micronized (2-{4-[2-(4-Diethylamino-2-hydroxy-benzoyl)-benzoyl]-piperazine-1-carbonyl}-phenyl)-(4-diethylamino-2-hydroxy-phenyl)-methanone; (b15) benzoicacid,4,4-[[3-[1,3,3,3-tetramethyl-1-[trimethylsilyl)oxy]-1-disiloxanyl]propyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, dibutyl ester wherein the UV filter combination comprises at least 2 UV filters of component (b1)-(b14); for the protection of human and animal hair and skin against UV radiation.
摘要翻译: 公开了使用UV过滤器组合,其包含(a)选自式(1)的亚苄基丙二酸酯的第一UV过滤器,其中R 1甲基; 乙基; 丙基; 或正丁基; 如果R1是甲基,那么R是叔丁基。 丁基; 式(II); 式(III); 式(1a)的基团; 或式(1b)的基团; 其中R2和R3彼此独立地是氢; 或甲基; R4是甲基; 乙基; 或正丙基; R5和R6彼此独立地是氢; 或C 1 -C 3烷基; 如果R1是乙基; 丙基; 或正丁基,那么R是异丙基; 和(b)选自(b1)双 - 乙基己氧基苯酚甲氧基苯基三嗪的第二UV过滤器; (b2)丁基甲氧基二苯甲酰甲烷; (b3)丁酰己二酸二乙基己酯; (b4)乙基己基三嗪酮; (b5)二乙基氨基羟基苯甲酰己基苯甲酸酯; (b6)甲氧基肉桂酸乙基己酯; (b7)水杨酸乙基己酯; (b8)均质酸; (b9) (b10)微米亚甲基双苯并三唑基四甲基丁基苯酚; (b11)苯基苯并咪唑磺酸; (b12)二氧化钛; (b13)微粉化的三联苯三嗪; 和(b14)微粉化(2- {4- [2-(4-二乙基氨基-2-羟基 - 苯甲酰基) - 苯甲酰基] - 哌嗪-1-羰基} - 苯基) - (4-二乙基氨基-2-羟基 - 苯基) 甲酮 (b15)苯甲酸,4,4 - [[3- [1,3,3,3-四甲基-1- [三甲基甲硅烷基]氧基] -1-二硅氧烷基]丙基]氨基] -1,3,5-三嗪-2 ,4-二基]二亚氨基]双 - 二丁酯,其中UV滤光器组合包含至少2个组分(b1) - (b14)的UV滤光剂; 用于保护人和动物的头发和皮肤免受紫外线辐射。
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公开(公告)号:US08044058B2
公开(公告)日:2011-10-25
申请号:US12715839
申请日:2010-03-02
申请人: Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
发明人: Barbara Wagner , Frank Bienewald , Heinz Wolleb , Olof Wallquist , Bernd Herzog , Thomas Ehlis , Jürg Haase
IPC分类号: A61K31/517 , A61K31/445 , A61K31/16
CPC分类号: A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要: Disclosed is the use of merocyanine derivatives of formula Q is hydrogen; C1-C22alkyl; —OH; —OR7; —NR7R8; or —N═R9; R1 is hydrogen; C1-C22alkyl; —OR7, —SR7; —NR7R8; C1-C22alkyl; C2-C12 alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; —(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si—R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); —(CH2)u—O—(CH2)v—SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; for protecting of human hair and skin against the damaging effect of UV radiation.
摘要翻译: 披露式Q的部花青衍生物的用途是氢; C 1 -C 22烷基; -哦; -OR7; -NR7R8; 或-N = R9; R1是氢; C 1 -C 22烷基; -OR7,-SR7; -NR7R8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12杂烷基,C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7,COOR7; CONR7R8; SO2(C6-C12)芳基; C2-C12烷-1-烯基; C 3 -C 12环烯-1-烯基; C2-C12alk-1-inyl; C 2 -C 12杂烷基; C3-C5杂环烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R5为-COR7; -COOR7; -OR7; -SR 7,-NHR 7,-NR 7 R 8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12烷基苯基; C 1 -C 12烷氧基-C 6 -C 10芳基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C 3 -C 12环杂烷基; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C 1 -C 22烷基; C1-C22烷氧基; 或COR7; R 7和R 8彼此独立地是氢; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; - (CH 2)t COOH; C7-C12芳烷基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C6-C10芳基; C1-C9杂芳基; Si-R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); - (CH 2)u -O-(CH 2)v -SiR 10 R 11 R 12; 或基团X-Sil; t,u和v彼此独立地为1至5的数; R9是(C1-C6)亚烷基; R 10,R 11,R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。
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公开(公告)号:US07179924B2
公开(公告)日:2007-02-20
申请号:US11046913
申请日:2005-01-31
申请人: Thomas Ehlis
发明人: Thomas Ehlis
IPC分类号: C07D249/04
CPC分类号: C08K5/3475 , A61K8/4966 , A61Q17/04 , C07D249/20
摘要: The use of benzotriazole UV absorbers of formula wherein A is a radical of formula B is a radical of formula R1, R2, R3, R4, R5 and R6 are each independently of the others hydrogen, C1–C16 alkyl; C5–C7cycloalkyl; halogen; R9 is hydrogen, C1–C12alkyl; or C5–C7cycloalkyl; R7, R8 and R10 are each independently of the others hydrogen, C1C12alkyl, C5–C7cycloalkyl, C1–C12hydroxyalkyl; X is halogen; a radical of formula (1s) sulfate, phosphate, lactate, citrate, tartrate; R11 is C1–C12alkyl; or C5–C7cycloalkyl; R12 and R13 are each independently of the other hydrogen; or C1–C5alkyl; x is from 0 to 10; and y is from 1 to 20; in the cosmetic treatment of human hair for protection against UV radiation is described.
摘要翻译: 使用下式的苯并三唑UV吸收剂其中A是式B的基团是式R 1,R 2,R 3, R 4,R 5和R 6各自独立地为氢,C 1 -C 3烷基, 烷基; C 5 -C 7环烷基; 卤素; R 9是氢,C 1 -C 12烷基; 或C 5 -C 7环烷基; R 7,R 8和R 10各自独立地为氢,C 1 -C 10烷基, C 1 -C 12烷基,C 5 -C 7环烷基,C 1 -C 12羟烷基,C 1 -C 12烷基, X是卤素; 硫酸盐,磷酸盐,乳酸盐,柠檬酸盐,酒石酸盐的式(1s)基团; R 11是C 1 -C 12烷基; 或C 5 -C 7环烷基; R 12和R 13各自独立地为氢; 或C 1 -C 5烷基; x为0〜10; y为1〜20; 在描述用于防止UV辐射的人发的美容处理中。
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