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公开(公告)号:US20100150831A1
公开(公告)日:2010-06-17
申请号:US12612638
申请日:2009-11-04
申请人: Xi Chen , Pingchen Fan , Mark M. Gleason , Juan C. Jaen , Lianfa Li , Jeffrey P. McMahon , Jay Powers , Yibin Zeng , Penglie Zhang
发明人: Xi Chen , Pingchen Fan , Mark M. Gleason , Juan C. Jaen , Lianfa Li , Jeffrey P. McMahon , Jay Powers , Yibin Zeng , Penglie Zhang
IPC分类号: A61K51/04 , C07D243/08 , A61K31/551 , C07D403/14 , A61P35/00
CPC分类号: C07D417/14 , C07D401/14
摘要: Compounds having formula I, or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present invention provides in further aspects, compositions containing one or more of the above-noted compounds in admixture with a pharmaceutically acceptable excipient.