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公开(公告)号:US20070123522A1
公开(公告)日:2007-05-31
申请号:US11538762
申请日:2006-10-04
申请人: John Hutchinson , Petpiboon Prasit , Mark Moran , Jillian Evans , Jasmine Zunic , Nicholas Stock
发明人: John Hutchinson , Petpiboon Prasit , Mark Moran , Jillian Evans , Jasmine Zunic , Nicholas Stock
IPC分类号: A61K31/5415 , A61K31/541 , A61K31/5377 , A61K31/538 , A61K31/4745 , A61K31/519 , C07D498/02 , C07D491/02 , C07D471/02
CPC分类号: C07D491/02 , C07D471/04 , C07D498/02
摘要: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.