公开(公告)号：US20120157879A1

公开(公告)日：2012-06-21

申请号：US13352069

申请日：2012-01-17

申请人： Joseph L. Mark ,  Brian C. Dougherty ,  Alexandra Schwier

发明人： Joseph L. Mark ,  Brian C. Dougherty ,  Alexandra Schwier

IPC分类号： A61B10/02 ,  A01N1/02

CPC分类号： G01N1/31 ,  A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/320783 ,  A61B18/02 ,  A61B90/40 ,  A61B2010/0208 ,  A61B2017/00017 ,  A61B2017/00977 ,  A61B2018/00005 ,  A61B2217/005 ,  A61B2217/007

摘要： A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described, as well as alternative systems for tissue preservation and transport. The cutting device includes an outer cannula in which a reciprocating inner cannula is disposed. A tissue collector is also provided and is in fluid communication with the lumen of the inner cannula. A temperature control sleeve may be disposed around the tissue collector to control the temperature of the tissue samples. A preservation system may be supplied that is configured to deliver fluids to tissue samples in the tissue collector. A fluid supply sleeve may be disposed about the outer cannula and is selectively positionable along the length of the outer cannula.

摘要翻译： 公开和描述了特别适用于神经外科应用的组织切割装置，以及组织保存和运输的替代系统。 切割装置包括外套管，其中设置往复式内套管。 还提供组织收集器并与内套管的内腔流体连通。 温度控制套管可以设置在组织收集器周围以控制组织样本的温度。 可以提供保存系统，其被配置为将流体输送到组织收集器中的组织样本。 流体供应套筒可以围绕外套管设置并且可以沿着外套管的长度选择性地定位。

公开(公告)号：US07988642B2

公开(公告)日：2011-08-02

申请号：US12039364

申请日：2008-02-28

申请人： Terry D. Hardin ,  Joseph L. Mark ,  William O. Hodge ,  Zachary R. Nicoson ,  Michael E. Miller

发明人： Terry D. Hardin ,  Joseph L. Mark ,  William O. Hodge ,  Zachary R. Nicoson ,  Michael E. Miller

IPC分类号： A61B10/02

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B2010/0208

摘要： A biopsy device is disclosed that comprises a cutting element mounted to a handpiece and a vacuum chamber. The cutting element comprises a stylet assembly and an outer cannula assembly. The stylet assembly includes a stylet that includes an open proximal end and a tissue opening at a distal end thereof. The tissue receiving opening is in communication with a lumen extending through the stylet. The outer cannula assembly includes an outer cannula that is slidably mounted over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. The stylet is selectively advanced distally outwardly with respect to outer cannula to expose the tissue opening to targeted tissue. The outer cannula is selectively advanced over the tissue opening to sever tissue, while vacuum is generated in the vacuum chamber and delivered to the tissue opening through the lumen. The vacuum causes tissue to be drawn into and maintained in the tissue opening while the outer cannula severs tissue to obtain a biopsy core.

摘要翻译： 公开了一种活检装置，其包括安装到手持件和真空室的切割元件。 切割元件包括探针组件和外套管组件。 探针组件包括探针，该探针包括开放的近端和在其远端的组织开口。 组织接收口与延伸穿过通丝针的内腔连通。 外套管组件包括外套管，其可滑动地安装在通球针上方并且具有形成在其上的切削刃的敞开的远端。 真空室与探针的内腔连通。 探针相对于外套管选择性向外远端向外推进，以将组织开口暴露于目标组织。 选择性地将外套管推进到组织开口上以切断组织，同时在真空室中产生真空并通过内腔输送到组织开口。 真空使得组织被拉入并保持在组织开口中，同时外套管切断组织以获得活组织检查核心。

公开(公告)号：US20110004119A1

公开(公告)日：2011-01-06

申请号：US12496316

申请日：2009-07-01

申请人： Michael Hoffa ,  Michael E. Miller ,  Joseph L. Mark ,  Jacob Flagle ,  Justin Smith ,  Jason M. Butcher

发明人： Michael Hoffa ,  Michael E. Miller ,  Joseph L. Mark ,  Jacob Flagle ,  Justin Smith ,  Jason M. Butcher

IPC分类号： A61B10/02

CPC分类号： A61B10/0283 ,  A61B10/0275 ,  A61B2010/0093 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/00477 ,  A61B2090/064

摘要： A surgical device is disclosed that comprises a cutting element, a biopsy line, a motor line, and a vacuum line. The cutting element includes an outer cannula and an inner cannula. The biopsy line is operatively connected to a control console for moving the inner cannula within the outer cannula to cut tissue cores. The motor line is operatively connected to the control console for operating the surgical device. The vacuum line is operatively connected to the inner cannula. A selectively openable tissue filter is operatively connected to the inner cannula, and is also connected to the vacuum line.

摘要翻译： 公开了一种包括切割元件，活检线，马达线和真空线的手术装置。 切割元件包括外套管和内套管。 活检线可操作地连接到控制台，用于移动外套管内的内套管以切割组织芯。 电动机线路可操作地连接到用于操作外科装置的控制台。 真空管线可操作地连接到内套管。 可选择打开的组织过滤器可操作地连接到内套管，并且还连接到真空管线。

公开(公告)号：US07841990B2

公开(公告)日：2010-11-30

申请号：US11279258

申请日：2006-04-11

申请人： Joseph L. Mark ,  Michael E. Miller

发明人： Joseph L. Mark ,  Michael E. Miller

IPC分类号： A61B10/00

CPC分类号： A61B10/0275 ,  A61B2010/0208 ,  A61B2010/045

摘要： A biopsy device includes a flexible distal portion for obtaining a biopsy sample. The device includes a coring cannula defining a coring relief notch adjacent its distal end having a length longer than a diameter of the cannula. A wire is slidably disposable within the lumen of the coring cannula and defines a sampling cavity adjacent its distal end. A wire relief notch is positioned adjacent the sampling cavity that has a length longer than its width. A firing mechanism engaged to the proximal ends of the coring cannula and the wire is operable to move the coring cannula relative to the wire between a first position retracted within the lumen so that the coring cannula covers the sampling cavity and a second position wherein the distal end of the wire is extended away from the coring cannula to trap tissue from the biopsy site in the cavity.

摘要翻译： 活检装置包括用于获得活检样本的柔性远端部分。 该装置包括一个取芯套管，其定义邻近其远端的取心凹口，其长度大于套管的直径。 线可滑动地一次性在取心套管的内腔内并且在其远端附近限定采样腔。 电线释放槽口位于采样腔的相邻处，其长度大于其宽度。 接合到取心套管和线的近端的击发机构可操作以在缩回到内腔内的第一位置之间相对于线移动取心套管，使得取心套管覆盖取样腔，而第二位置，其中远端 导线的端部从取芯插管延伸以从腔中的活检部位捕获组织。

公开(公告)号：US20100280409A1

公开(公告)日：2010-11-04

申请号：US12834448

申请日：2010-07-12

申请人： Joseph L. Mark

发明人： Joseph L. Mark

IPC分类号： A61B10/02

CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00035 ,  A61B2017/00057 ,  A61B2017/00084 ,  A61B2017/00115

摘要： A system for detecting tissue in a patient is disclosed. The system includes an introducer assembly, a surgical instrument and a sensor element. In one configuration, the introducer assembly has a first delivery lumen and a secondary lumen. The surgical instrument is configured for resecting tissue from a patient, and is received within the first delivery lumen. The sensor element is configured to detect at least one property of the tissue of said patient. The sensor being positioned within the secondary lumen so as to contact tissue.

摘要翻译： 公开了一种用于检测患者组织的系统。 该系统包括导引器组件，外科器械和传感器元件。 在一种构造中，导引器组件具有第一输送腔和辅助腔。 外科器械被配置为从患者切除组织，并且被接收在第一递送腔内。 传感器元件被配置为检测所述患者的组织的至少一个属性。 传感器定位在次内腔内，以便接触组织。

公开(公告)号：US20100249817A1

公开(公告)日：2010-09-30

申请号：US12782879

申请日：2010-05-19

申请人： Joseph L. Mark

发明人： Joseph L. Mark

IPC分类号： A61B17/32

CPC分类号： A61B17/32002 ,  A61B1/313 ,  A61B10/0275 ,  A61B10/0283 ,  A61B34/20 ,  A61B34/70 ,  A61B90/11 ,  A61B90/50 ,  A61B2010/0208 ,  A61B2017/00398 ,  A61B2017/306 ,  A61B2017/320028 ,  A61B2017/3445 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2090/3983 ,  A61B2217/005

摘要： A tissue cutting device especially suited for neurosurgical applications is disclosed and described. The device includes a handpiece and an outer cannula in which a reciprocating inner cannula is disposed. At least one position transducer for tracking a location in space of the tissue cutting device is rigidly associated with the handpiece. The position transducer is operable for sending a signal indicative of a location of a distal end of the outer cannula. The tissue cutting device may also include an angular position sensor for determining an angular position of the outer cannula relative to the position transducer.

摘要翻译： 公开并描述了特别适用于神经外科应用的组织切割装置。 该装置包括手柄和外套管，其中设置有往复式内插管。 用于跟踪组织切割装置的空间中的位置的至少一个位置传感器与手持件刚性地相关联。 位置传感器可操作用于发送指示外套管的远端的位置的信号。 组织切割装置还可以包括用于确定外套管相对于位置换能器的角位置的角位置传感器。

公开(公告)号：US07798331B2

公开(公告)日：2010-09-21

申请号：US12033967

申请日：2008-02-20

申请人： Terry D. Hardin ,  Joseph L. Mark

发明人： Terry D. Hardin ,  Joseph L. Mark

IPC分类号： B65D6/04 ,  A61B17/02 ,  A61B10/02

CPC分类号： A61B10/0096 ,  A61B50/33

摘要： A tissue collection tray is described for use with a biopsy device. The tissue collection tray includes a well portion, a body portion and a divider. The well portion is defined by first and second ends, a bottom and at least two walls. The body portion includes a recess formed therein. The divider includes a groove formed therein. The divider is positioned between the recess and the well portion.

摘要翻译： 描述了用于活检装置的组织收集托盘。 组织收集托盘包括井口部分，主体部分和分隔部。 井部分由第一和第二端，底部和至少两个壁限定。 主体部分包括形成在其中的凹部。 分隔器包括形成在其中的凹槽。 分隔件位于凹部和井部之间。

公开(公告)号：US20100081964A1

公开(公告)日：2010-04-01

申请号：US12241644

申请日：2008-09-30

申请人： Joseph L. Mark ,  Michael E. Miller

发明人： Joseph L. Mark ,  Michael E. Miller

IPC分类号： A61B10/02

CPC分类号： A61B10/0275 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0091 ,  A61B10/0283 ,  A61B2017/00022 ,  A61B2017/00057 ,  A61B2017/00061

摘要： A system for detecting abnormal tissue in a patient including an introducer cannula having a proximal opening and a distal opening. The system further includes a surgical instrument configured for selective insertion through the cannula. The surgical instrument further includes a tissue cutting opening positioned relative to the distal end of the introducer cannula when fully inserted through the introducer cannula. The system also includes a sensor configured to detect at least one property of the tissue of the patient. The sensor is located at a fixed distance relative to the distal end of the introducer cannula when the surgical instrument is inserted into the introducer cannula.

摘要翻译： 一种用于检测患者中异常组织的系统，包括具有近端开口和远端开口的导引套管。 该系统还包括构造成用于通过套管选择性插入的手术器械。 手术器械还包括当完全插入通过导引套管时相对于导引套管的远端定位的组织切割开口。 该系统还包括被配置为检测患者组织的至少一个特性的传感器。 当外科器械插入导引套管中时，传感器相对于导引套管的远端位于固定的距离处。

公开(公告)号：US20090192408A1

公开(公告)日：2009-07-30

申请号：US12020921

申请日：2008-01-28

申请人： Joseph L. Mark

发明人： Joseph L. Mark

IPC分类号： A61B10/00

CPC分类号： A61B90/39 ,  A61B10/0275 ,  A61B2090/0811 ,  A61B2090/3987

摘要： A marker delivery system is provided that includes a delivery tube and a push rod. The delivery tube is defined by distal and proximal ends and includes a distal opening that communicates with a lumen extending through the delivery tube and a curved distal end portion. The distal opening is positioned distally of the curved distal end portion. The push rod is configured for slidable engagement within the lumen of the delivery tube and is sized to extend to at least the distal opening of the delivery tube when the push rod is fully inserted within the delivery tube to push out one or more site markers disposed within the lumen of the delivery tube.

摘要翻译： 提供了包括输送管和推杆的标记输送系统。 输送管由远端和近端限定，并且包括与延伸穿过输送管的内腔连通的远端开口和弯曲的远端部分。 远端开口位于弯曲的远端部分的远侧。 推杆构造成用于在输送管的内腔内可滑动地接合，并且当推杆完全插入输送管内时，其尺寸被设计成延伸至至少输送管的远端开口以推出一个或多个位置标记 在输送管的内腔内。

公开(公告)号：US20090088666A1

公开(公告)日：2009-04-02

申请号：US11865092

申请日：2007-10-01

申请人： Michael E. Miller ,  Jake Flagle ,  Joseph L. Mark ,  Zachary R. Nicoson

发明人： Michael E. Miller ,  Jake Flagle ,  Joseph L. Mark ,  Zachary R. Nicoson

IPC分类号： A61B10/02

CPC分类号： A61B10/0275 ,  A61B90/50 ,  A61B2010/0208 ,  Y10T403/22

摘要： A surgical device is disclosed. The surgical device comprises a housing, a cutting element, a spool, a piston, and a spring. The cutting element extends from the housing at the distal end of the housing. The cutting element comprises an outer cannula and an inner cannula. The spool is engaged with the outer cannula. The piston is engaged with the inner cannula. A spring is positioned between the spool and the piston. The spool is translated distally to translate the outer cannula towards the distal end. And the piston translates the inner cannula towards the distal end to sever tissue.

摘要翻译： 公开了一种手术装置。 手术装置包括壳体，切割元件，线轴，活塞和弹簧。 切割元件在壳体的远端处从壳体延伸。 切割元件包括外套管和内套管。 阀芯与外套管接合。 活塞与内套管接合。 弹簧定位在阀芯和活塞之间。 线轴向远端平移以将外套管朝远端平移。 并且活塞将内套管朝向远端平移以切断组织。