公开(公告)号：US20200017509A1

公开(公告)日：2020-01-16

申请号：US16448083

申请日：2019-06-21

Applicant: NovMetaPharma Co., Ltd.

Inventor： Kay Olmstead ,  David Pearson ,  Elaine McPherson

IPC: C07D487/04

Abstract: The present disclosure relates to synthesis and characterization of novel polymorphic forms of Cyclo (-His-Pro) (“CHP”).

公开(公告)号：US20190290720A1

公开(公告)日：2019-09-26

申请号：US16316595

申请日：2017-07-13

Applicant: NOVMETAPHARMA CO., LTD.

Inventor： Hoe-Yune Jung ,  Heon-Jong Lee ,  Jong-Su Jeon ,  Yon-Su Kim ,  Seung-Hee Yang ,  Yong-Chul Kim ,  Jong-Joo Moon ,  Hwan-Soo Yoo ,  Kyeong-Mi Choi

IPC: A61K38/12 ,  C07K5/12 ,  A61P31/00 ,  A61P35/00 ,  A23L33/18

Abstract: The present disclosure relates to a cell-protecting pharmaceutical composition including a cyclo histidine-proline (Cyclo His-Pro, CHP) as an active ingredient. The cell-protecting pharmaceutical composition including the present cyclo histidine-proline (CHP) as an active ingredient has an excellent protective effect to protect kidney and liver cells from toxicity. Thus, the composition may be useful for the prevention or treatment of kidney and liver diseases.