Multifunctional compounds for pharmaceutical purposes
    41.
    发明授权
    Multifunctional compounds for pharmaceutical purposes 有权
    用于制药目的的多功能化合物

    公开(公告)号:US08470963B2

    公开(公告)日:2013-06-25

    申请号:US12305898

    申请日:2007-07-02

    申请人: Andre Koltermann

    发明人: Andre Koltermann

    IPC分类号: C07K14/00

    摘要: The invention relates to a synthetic bifunctional non-antibody compound comprising one or more effector moieties and one or more binder moieties, wherein the effector moieties are operably linked to the binder moieties via a linker, the effector moieties are ligands to at least one pathogen pattern recognition receptor (PRR) and the binder moieties bind to a marker of a tumor cell.

    摘要翻译: 本发明涉及包含一个或多个效应部分和一个或多个粘合剂部分的合成双功能非抗体化合物,其中效应部分通过连接体可操作地连接到粘合剂部分,效应部分是至少一种病原体模式的配体 识别受体(PRR)和粘合剂部分结合于肿瘤细胞的标志物。