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41.发明公开公开(公告)号：US20240082582A1
公开(公告)日：2024-03-14
申请号：US18497665
申请日：2023-10-30
Inventor： Que T. Doan , Luca Antonello Annecchino , Ismael Huertas Fernandez
CPC classification number: A61N1/36175 , A61N1/025 , A61N1/36062 , A61N1/36185
Abstract: New waveforms for use in an implantable pulse generator or external trial stimulator are disclosed which mimic actively-driven biphasic pulses, and which are particularly useful for issuing low frequencies pulses. The waveforms comprise at each electrode interleaved first and second pulses. Each first pulse comprises a first monophasic pulse and a first passive charge recovery period. Each second pulse comprises a second monophasic pulse with a polarity opposite the first monophasic pulse and a second passive charge recovery period. Preferably, the amplitudes and pulse widths of the first and second monophasic pulses are equal, or at least charge balanced at each electrode. The first and second monophasic pulses mimic the functionality of a symmetric biphasic pulse, with the first monophasic pulse mimicking the functionality of the biphasic pulse's first phase, and the with the second monophasic pulse mimicking the functionality of the biphasic pulse's second phase.
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公开(公告)号：US11547861B2
公开(公告)日：2023-01-10
申请号：US16568063
申请日：2019-09-11
Abstract: A system may be used with a medical imaging system and a programming system. The medical imaging system may be configured to display a medical image and the programming system may be configured to implement a program used in programming a neuromodulation device. The system may comprise a mobile device having at least one processor, a camera and a user interface including a display. The mobile device may be configured to acquire a displayed medical image from the medical imaging system, determine based on the acquired medical image location data indicative of the position of at least one of the electrodes relative to at least one of the anatomy or at least another one of the electrodes, and provide the location data for use by the program implemented by the programming system.
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公开(公告)号：US11338141B2
公开(公告)日：2022-05-24
申请号：US16806065
申请日：2020-03-02
Inventor： Que T. Doan , Jianwen Gu , Ismael Huertas Fernandez , Rosana Esteller , Michael A. Moffitt
Abstract: Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain. Beneficially, sub-perception stimulation at such low frequencies significantly lowers power consumption in the patient's neurostimulator.
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公开(公告)号：US20210046314A1
公开(公告)日：2021-02-18
申请号：US17089538
申请日：2020-11-04
Inventor： Que T. Doan , Jianwen Gu , Ismael Huertas Fernandez , Rosana Esteller , Michael A. Moffitt
Abstract: Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain. Beneficially, sub-perception stimulation at such low frequencies significantly lowers power consumption in the patient's neurostimulator.
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公开(公告)号：US20200215330A1
公开(公告)日：2020-07-09
申请号：US16736580
申请日：2020-01-07
Inventor： Ismael Huertas Fernandez , Que T. Doan
Abstract: An example of a system for controlling delivery of neurostimulation from a stimulation device to a patient according to a selected neurostimulation program may include a programming device. The programming device may be configured to be communicatively coupled to the stimulation device and to select the neurostimulation program. The programing device may include a user interface and a program selection circuit. The program selection circuit may be configured to receive life factor information indicative of at least one of an environmental factor and a biopsychosocial factor of the patient, to select the neurostimulation program from a plurality of neurostimulation programs based on the received life factor information, to present a recommendation using the user interface based on the selected neurostimulation program, and to receive a user command responding to the recommendation using the user interface.
