专利检索 ap:("Dieter-Bernd Reuschling" OR "Klaus Kuhlein" OR "Bernward Scholkens" OR "Rudolf Kunstmann" OR "Ulrich Lerch" OR "Wilhelm Bartmann" OR "Hermann Teufel" OR "Gerhard Beck") AND inv:"Wilhelm Bartmann" 第 5 页

41.

发明授权
Isoquinoline derivatives, processes for their manufacture and their use for the manufacture of medicaments 失效
标题翻译：异喹啉衍生物，其制造方法及其用于制造药物的用途

公开(公告)号：US4282223A

公开(公告)日：1981-08-04

申请号：US76862

申请日：1979-09-19

申请人： Wilhelm Bartmann , Elmar Konz , Hansjorg Kruse , Harry M. Geyer

发明人： Wilhelm Bartmann , Elmar Konz , Hansjorg Kruse , Harry M. Geyer

IPC分类号： A61K31/47 , A61K31/472 , A61K31/495 , A61K31/535 , A61P25/08 , A61P25/20 , C07D217/22 , C07D217/26 , C07D401/04 , C07D401/12 , C07D405/12 , C07D413/04 , C07D413/12

CPC分类号： C07D217/26 , C07D217/22

摘要： Isoquinolines of the formula ##STR1## of which representative compounds are such as 3-N-methylpiperazino-1-phenyl-isoquinoline-4-aldehyde, 3-N-methylpiperazino-1-(2-fluorophenyl)-isoquinoline-4-aldehyde, or 3-N-[3-(4-fluoro-benzoyl)-propyl]-piperazino-1-phenyl-isoquinoline-4-aldehyde and medicaments containing the isoquinolines which are useful as antidepressants.

摘要翻译： 其代表性化合物为3-N-甲基哌嗪-1-基 - 异喹啉-4-醛，3-N-甲基哌嗪-1-（2-氟苯基） - 异喹啉-4-醛的式（VI）的异喹啉，或3-N- [3-（4-氟 - 苯甲酰基） - 丙基] - 哌嗪-1-基 - 异喹啉-4-醛和包含可用作抗抑郁药的异喹啉的药物。