公开(公告)号：US20220395638A1

公开(公告)日：2022-12-15

申请号：US17839647

申请日：2022-06-14

Applicant: INSULET CORPORATION

Inventor： Yibin ZHENG ,  Joon Bok LEE ,  Ashutosh ZADE ,  Jason O'CONNOR

IPC: A61M5/172

Abstract: The disclosed embodiments are directed to methods for adjusting, on a per individual basis, the maximum delivery limit of insulin delivered to a diabetic person via an automatic insulin delivery system, particularly for a diabetic who receives basal or bolus doses of insulin via an automatic insulin delivery system. Various embodiments of the method disclosed herein may be incorporated into a dosing algorithm of an automatic insulin delivery system.

公开(公告)号：US20220331519A1

公开(公告)日：2022-10-20

申请号：US17718663

申请日：2022-04-12

Applicant: Insulet Corporation

Inventor： Joon Bok LEE ,  Yibin ZHENG ,  Jason O'CONNOR ,  Ashutosh ZADE

IPC: A61M5/172 ,  A61B5/145 ,  A61B5/1495 ,  A61M5/142 ,  G16H40/40

Abstract: Exemplary embodiments may compensate for loss of calibration by sensors that provide sensed analyte measurements to delivery devices. The exemplary embodiments may obtain one or more calibrated analyte measurements, such as by using techniques to obtain that the analyte measurement value that are known to produce properly calibrated analyte values. The one or more calibrated analyte measurements are compared to a recent analyte measurement to determine a negative or positive offset. The offset may be added to the recent analyte measurement to generate an updated analyte measurement that reflects the calibrated analyte measurement. In addition, past analyte measurement values within a time window may be updated as well by adding the offset to the past analyte measurement values. The exemplary embodiments may also compensate for the past over-delivery or under-delivery of an agent by the delivery device due to the loss of calibration.

公开(公告)号：US20220226576A1

公开(公告)日：2022-07-21

申请号：US17715589

申请日：2022-04-07

Applicant: INSULET CORPORATION

Inventor： Yibin ZHENG ,  Joon Bok LEE ,  Ashutosh ZADE ,  Jason O'CONNOR

IPC: A61M5/172 ,  G06F17/17

Abstract: Exemplary embodiments may address the problem of missing blood glucose concentration readings from a glucose monitor that transmits blood glucose concentration readings over a wireless connection due to problems with the wireless connection. In the exemplary embodiments, an automated insulin delivery (AID) device uses an estimate in place of a missing blood glucose concentration reading in determining a predicted future blood glucose concentration reading for a user. Thus, the AID device is able to operate normally in generating insulin delivery settings despite not receiving a current blood glucose concentration reading for a current cycle. There is no need to suspend delivery of insulin to the user due to the missing blood glucose concentration reading.

公开(公告)号：US20220062545A1

公开(公告)日：2022-03-03

申请号：US17008054

申请日：2020-08-31

Applicant: Insulet Corporation

Inventor： Ashutosh ZADE ,  Joon Bok LEE ,  Yibin ZHENG

IPC: A61M5/172 ,  A61M5/142 ,  A61K38/28

Abstract: Techniques and devices for determining and generating insulin formulations are described. An automated insulin delivery device may include a wireless interface with a glucose sensor for providing blood glucose concentration readings of a user, a plurality of insulin reservoirs, each of the plurality of insulin reservoirs holding a different one of a plurality of insulin types, each of the plurality of insulin types having a different strength, a storage medium storing programming instructions and user glucose information, the user glucose information comprising the blood glucose concentration readings, predicted future blood glucose concentration readings, and user activity information, determining an insulin strength based on the user glucose information, determining an insulin formulation ratio to generate an insulin formulation having the insulin strength using the plurality of insulin types, an insulin formulation device to generate the insulin formulation; and an insulin delivery component to deliver the insulin formulation to the user.

公开(公告)号：US20220061706A1

公开(公告)日：2022-03-03

申请号：US17003854

申请日：2020-08-26

Applicant: Insulet Corporation

Inventor： Ashutosh ZADE ,  Joon Bok LEE ,  Yibin ZHENG ,  Steven CARDINALI

IPC: A61B5/145 ,  A61M5/172 ,  A61B5/00 ,  A61K38/28

Abstract: Methods and apparatuses for performing a blood glucose monitoring process are described. For example, an apparatus may include at least one memory and logic coupled to the at least one memory. The logic may operate to determine patient monitoring information associated with a diabetic treatment of a patient, generate at least one monitoring information structure based on the patient monitoring information, generate at least one monitoring information image based on at least a portion of the at least one monitoring information structure, and process the at least one monitoring information image using a computational model to determine a blood glucose condition of the patient. Other embodiments are described.

公开(公告)号：US20210259590A1

公开(公告)日：2021-08-26

申请号：US16796575

申请日：2020-02-20

Applicant: Insulet Corporation

Inventor： Thomas METZMAKER ,  Nicholas CONTE ,  Ian MCLAUGHLIN ,  Joon Bok LEE ,  Paul Frederick BENTE ,  Ashutosh ZADE ,  Steven CARDINALI

IPC: A61B5/145 ,  A61B5/00 ,  G16H20/60 ,  G16H40/63 ,  G16H40/67

Abstract: Disclosed are examples that include receiving information related to ingestion of a meal. The information may include a coarse indication of a size of the meal, a relative time of ingestion of the meal, and a general composition indication of the meal. A blood glucose measurement value received within a predetermined time range of a relative time of ingestion of the meal may be identified. Settings for a delay and an extend parameter and a delivery constraint may be determined. A meal model may be modified using the determined settings for the delay parameter, the extend parameter, and the delivery constraint. The modified meal model may be used to determine a dose of insulin to be delivered in response to the received information. An instruction indicates a determined dose of insulin to be delivered may be output for delivery to a drug delivery device.

公开(公告)号：US20210252219A1

公开(公告)日：2021-08-19

申请号：US16791648

申请日：2020-02-14

Applicant: Insulet Corporation

Inventor： Yibin ZHENG ,  Joon Bok LEE ,  Ashutosh ZADE ,  Jason O'Connor

IPC: A61M5/172 ,  G06F17/17

Abstract: Exemplary embodiments may address the problem of missing blood glucose concentration readings from a glucose monitor that transmits blood glucose concentration readings over a wireless connection due to problems with the wireless connection. In the exemplary embodiments, an automated insulin delivery (AID) device uses an estimate in place of a missing blood glucose concentration reading in determining a predicted future blood glucose concentration reading for a user. Thus, the AID device is able to operate normally in generating insulin delivery settings despite not receiving a current blood glucose concentration reading for a current cycle. There is no need to suspend delivery of insulin to the user due to the missing blood glucose concentration reading.

公开(公告)号：US20210228804A1

公开(公告)日：2021-07-29

申请号：US17150461

申请日：2021-01-15

Applicant: Insulet Corporation

Inventor： Eric BENJAMIN ,  Joon Bok LEE ,  Yibin ZHENG ,  Jason O'CONNOR ,  Ashutosh ZADE

IPC: A61M5/172 ,  A61B5/145 ,  A61K38/28

Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide techniques to implement functionality to receive information related to a meal and delivery of a meal bolus. The received information may be stored and utilized in the generation of insulin delivery profiles. An estimate a mealtime insulin need based on the generated insulin delivery profiles may be generated. A dose of insulin may be determined that satisfies an estimated mealtime insulin need based on the generated insulin delivery profiles. The determined dose of insulin may be output at a time corresponding to a mealtime.