公开(公告)号：US06735323B1

公开(公告)日：2004-05-11

申请号：US10354020

申请日：2003-01-30

申请人： George Chang

发明人： George Chang

IPC分类号： H04R2500

CPC分类号： H04R7/20 ,  H04R9/043 ,  Y10T403/7182

摘要： A speaker includes a T-shape iron, a ring magnet, a pole plate, a frame, a diaphragm, a coil core portion, a voice coil, a first annular corrugated plate, and at least one second annular corrugated plate. The second annular corrugated plate has is bonded to an inner side or an outer side of an outer section of the first annular corrugated plate and spaced from the coil core portion, thereby increasing a thickness and strength of an outer section of the first annular corrugated plate for bearing higher power such that the speaker generates clear sound and that an inner section of the first annular corrugated plate generates sufficient sound pressure when a power outputted by the speaker is low.

摘要翻译： 扬声器包括T形铁，环形磁铁，极板，框架，隔膜，线圈芯部分，音圈，第一环形波纹板和至少一个第二环形波纹板。 第二环形波纹板已经结合到第一环形波纹板的外部部分的内侧或外侧并与线圈芯部分间隔开，从而增加第一环形波纹板的外部部分的厚度和强度 用于承受更高的功率，使得扬声器产生清晰的声音，并且当扬声器输出的功率低时，第一环形波纹板的内部部分产生足够的声压。

公开(公告)号：US06486182B1

公开(公告)日：2002-11-26

申请号：US09577561

申请日：2000-05-24

申请人： George Chang ,  Ernest S. Hamanaka ,  John L. LaMattina

发明人： George Chang ,  Ernest S. Hamanaka ,  John L. LaMattina

IPC分类号： A61K314439

CPC分类号： C07D401/12 ,  A61K47/55 ,  C07D405/14

摘要： This invention relates to mutual prodrugs of amlodipine and atorvastatin and to pharmaceutical compositions thereof. This invention also relates to methods of treating angina pectoris, atherosclerosis, and hypertension and hyperlipidemia in a mammal using those prodrugs and compositions. This invention also relates to methods of managing cardiac risk in a mammal, including humans, presenting with symptoms of cardiac risk by administering those prodrugs and compositions.

摘要翻译： 本发明涉及氨氯地平和阿托伐他汀的联合前体药物及其药物组合物。 本发明还涉及使用这些前药和组合物治疗哺乳动物心绞痛，动脉粥样硬化，高血压和高脂血症的方法。 本发明还涉及通过施用那些前药和组合物来治疗患有心脏病风险的哺乳动物（包括人）的心脏风险的方法。

公开(公告)号：US06262092B1

公开(公告)日：2001-07-17

申请号：US09578204

申请日：2000-05-24

申请人： George Chang ,  Ernest S. Hamanaka

发明人： George Chang ,  Ernest S. Hamanaka

IPC分类号： A01N4340

CPC分类号： C07D207/335 ,  A61K31/40 ,  A61K31/44 ,  A61K31/4422 ,  A61K31/48 ,  A61K47/55 ,  C07D207/416 ,  C07D211/90 ,  Y10S514/824 ,  A61K2300/00

摘要： This invention relates to a mutual salt of amlodipine and atorvastatin, pharmaceutical compositions thereof and methods of treating angina pectoris, atherosclerosis and combined hypertension and hyperlipidemia in mammals with such a mutual salt and compositions. This invention also relates to methods of managing cardiac risk in a mammal presenting with symptoms of cardiac risk, including humans by administering such a mutual salt and compositions.

摘要翻译： 本发明涉及氨氯地平和阿托伐他汀的相互盐，其药物组合物和哺乳动物用这种相互盐和组合物治疗心绞痛，动脉粥样硬化和组合高血压和高脂血症的方法。 本发明还涉及通过施用这种共同的盐和组合物来管理呈现心脏病风险的哺乳动物的心脏风险的方法，包括人类。