公开(公告)号：US07648838B2

公开(公告)日：2010-01-19

申请号：US11267005

申请日：2005-11-04

申请人： Chang-eun Yoo ,  Joon-ho Kim ,  Kyu-youn Hwang ,  Hun-joo Lee ,  Hee-kyun Lim ,  Soo-min Ma ,  Nam Huh ,  Soo-suk Lee

发明人： Chang-eun Yoo ,  Joon-ho Kim ,  Kyu-youn Hwang ,  Hun-joo Lee ,  Hee-kyun Lim ,  Soo-min Ma ,  Nam Huh ,  Soo-suk Lee

IPC分类号： G01N33/48 ,  G01N33/20 ,  G01N1/00

CPC分类号： C12Q1/6806 ,  Y10T436/25 ,  C12Q2523/308

摘要： Provided is a lysis method for cells or viruses, including: immobilizing a metal-ligand complex on a solid support; and mixing the complex immobilized on the support with a cell or virus solution. According to the lysis method, by immobilizing a chemical on a solid support to perform cell lysis, the dilution problem according to the addition of a cell lysis solution can be resolved and a separate process of removing the chemical is not required so as to reduce the steps upon LOC implementation. In addition, since a variety of solid supports, such as chips, beads, nanoparticles etc. can be used, cell lysis apparatuses of various forms can be fabricated.

摘要翻译： 提供了一种细胞或病毒的裂解方法，包括：将固定支持物上的金属 - 配体复合物固定; 并将固定在载体上的复合物与细胞或病毒溶液混合。 根据裂解方法，通过将化学物质固定在固体支持体上以进行细胞裂解，可以解决根据细胞溶解溶液的添加的稀释问题，并且不需要单独的除去化学品的方法，以减少 LOC实施步骤。 此外，由于可以使用各种固体支持物，例如芯片，珠粒，纳米粒子等，因此可以制造各种形式的细胞裂解装置。

公开(公告)号：US07579172B2

公开(公告)日：2009-08-25

申请号：US11071383

申请日：2005-03-03

申请人： Yoon-kyoung Cho ,  Joon-ho Kim ,  Kak Namkoong ,  Geun-bae Lim ,  Jun-hong Min

发明人： Yoon-kyoung Cho ,  Joon-ho Kim ,  Kak Namkoong ,  Geun-bae Lim ,  Jun-hong Min

IPC分类号： C12Q1/66 ,  C12P19/34

CPC分类号： G01N35/08 ,  B01F5/0646 ,  B01F5/0647 ,  B01F5/0654 ,  B01F13/0071 ,  B01F2015/0221 ,  B01J2219/00783 ,  B01J2219/00824 ,  B01J2219/00831 ,  B01J2219/00833 ,  B01J2219/00837 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00891 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0809 ,  B01L2300/0861 ,  B01L2300/0883 ,  G01N2035/00366 ,  G01N2035/00514

摘要： An apparatus for amplifying nucleic acids includes a substrate, a reaction vessel formed inside of the substrate, at least one first inlet channel formed inside the substrate, connected to an end of the reaction vessel, and allowing introduction of a reactant aqueous solution containing reactants for nucleic acid amplification into the reaction vessel, a second inlet channel formed inside the substrate, connected to the end of the reaction vessel, and allowing introduction of a fluid that is phase-separated from the reactant aqueous solution and does not participate in amplification reaction into the reaction vessel, and a heating unit installed on the substrate in such a way to thermally contact with the substrate and heating the substrate, wherein the reactant aqueous solution contacts the fluid to create a plurality of droplets surrounded by the fluid in the reaction vessel and the nucleic acids are amplified in the reactant aqueous solution droplets.

摘要翻译： 用于放大核酸的装置包括：基板，形成在基板内部的反应容器，形成在基板内部的至少一个第一入口通道，与反应容器的端部连接，并且允许引入含有反应物的反应物水溶液， 核酸扩增到反应容器中，形成在基底内的第二入口通道，连接到反应容器的末端，并允许引入与反应物水溶液相分离并且不参与扩增反应的流体 反应容器和加热单元，其以与基底热接触并加热基底的方式安装在基底上，其中反应物水溶液接触流体以产生由反应容器中的流体包围的多个液滴， 核酸在反应物水溶液液滴中被扩增。

公开(公告)号：US20090186578A1

公开(公告)日：2009-07-23

申请号：US12358013

申请日：2009-01-22

申请人： YOUNG HO KIM ,  JOON HO KIM ,  JAE HO KANG

发明人： YOUNG HO KIM ,  JOON HO KIM ,  JAE HO KANG

IPC分类号： H04B7/00

CPC分类号： H04M1/05 ,  H04M1/6066 ,  H04M2250/02

摘要： Disclosed herein is a hinge type Bluetooth ear set. The hinge type Bluetooth ear set has an ear phone hingably connected to a main body of the ear set. An antenna is provided by an antenna pattern formed on an antenna board independent of a main board. The antenna board is connected to the main board at a right angle and disposed in a space between a shaft support supporting the ear phone and an outer surface of the main body. The hinge type Bluetooth ear set has a reduced size of the main board. Further, the hinge type Bluetooth ear set has the antenna board disposed at a lateral side of the hinge shaft, enabling reduction of an overall size of the Bluetooth ear set while ensuring a suitable size of the antenna board.

摘要翻译： 本文公开了铰链型蓝牙耳机。 铰链式蓝牙耳机具有可铰接地连接到耳机主体的耳机。 由独立于主板的天线板上形成的天线图案提供天线。 天线板以直角连接到主板，并且设置在支撑耳机的轴支架和主体的外表面之间的空间中。 铰链式蓝牙耳机的主板尺寸减小。 此外，铰链式蓝牙耳机具有设置在铰链轴的侧面的天线板，能够在确保天线板的合适尺寸的同时降低蓝牙耳机的整体尺寸。

公开(公告)号：US20090098291A1

公开(公告)日：2009-04-16

申请号：US12100700

申请日：2008-04-10

申请人： Kyu-youn HWANG ,  Joon-ho Kim ,  Sung-young Jeong ,  Chin-sung Park

发明人： Kyu-youn HWANG ,  Joon-ho Kim ,  Sung-young Jeong ,  Chin-sung Park

IPC分类号： C23C16/44 ,  B05D1/36

CPC分类号： G01N33/54353 ,  C23C14/025 ,  C23C14/028 ,  C23C14/10 ,  G01N33/553

摘要： The present invention provides a method of manufacturing a solid support for biological analysis using a plastic material, the method including: depositing a metal film on a plastic substrate on which a microstructure is formed; depositing an inorganic oxide on the metal film; and anchoring a compound with an amino functional group or a compound with a water contact angle of 70 to 95 degrees on the inorganic oxide.

摘要翻译： 本发明提供一种使用塑料材料制造用于生物分析的固体支持物的方法，所述方法包括：在形成微结构的塑料基板上沉积金属膜; 在金属膜上沉积无机氧化物; 并且将具有氨基官能团的化合物或具有70至95度的水接触角的化合物锚定在无机氧化物上。

公开(公告)号：US07512958B2

公开(公告)日：2009-03-31

申请号：US11231935

申请日：2005-09-22

申请人： Tae Heon Kim ,  Jun Kun Choi ,  Nam Seok Kim ,  Joon Ho Kim ,  Chil Sung Lee

发明人： Tae Heon Kim ,  Jun Kun Choi ,  Nam Seok Kim ,  Joon Ho Kim ,  Chil Sung Lee

IPC分类号： G11B17/028

CPC分类号： G11B17/0282

摘要： The invention relates to an optical disk drive, and more particularly, to a holder for disk drives having an improved chuck structure for seating a disk. The holder of the invention, in use, is inserted into a central opening of a disk for detachably seating the disk, and comprises: a circular hub projected upward and sized equal to the central opening of the disk; a chuck projected from a lateral portion of the hub, wherein the chuck includes a rear portion elastically connected with the hub, a peak formed in a front portion of the chuck and a lower circular face of a curvature extended downward from the peak; and a support formed integral with the hub for contacting the lower circular face of the chuck to enable circular motion of the chuck.

摘要翻译： 本发明涉及一种光盘驱动器，更具体地说，涉及一种具有用于安置盘的改进的卡盘结构的盘驱动器的保持器。 本发明的保持器在使用中被插入到盘的中心开口中，用于可拆卸地安置盘，并且包括：向上突出并且尺寸等于盘的中心开口的圆形毂; 从所述轮毂的侧部突出的卡盘，其中所述卡盘包括与所述毂弹性连接的后部，形成在所述卡盘的前部的峰和从所述峰向下延伸的曲率的下圆形面; 以及与所述毂一体形成的支撑件，用于接触所述卡盘的下圆形面以使得所述卡盘能够圆周运动。

公开(公告)号：US20090005265A1

公开(公告)日：2009-01-01

申请号：US12141894

申请日：2008-06-18

申请人： Kyu-youn HWANG ,  Joon-ho KIM ,  Chang-eun YOO ,  Hun-joo LEE ,  Hee-kyun LIM ,  Sung-young JEONG ,  Jeo-young SHIM

发明人： Kyu-youn HWANG ,  Joon-ho KIM ,  Chang-eun YOO ,  Hun-joo LEE ,  Hee-kyun LIM ,  Sung-young JEONG ,  Jeo-young SHIM

IPC分类号： C40B40/04 ,  C07C63/26

CPC分类号： C12N15/1006 ,  B01D15/361 ,  B01D15/364 ,  B01J20/3285 ,  B01J43/00 ,  C12Q1/6806 ,  C12Q2527/119 ,  C12Q2523/308

摘要： A method of isolating nucleic acid from a sample containing nucleic acid is provided. The method includes contacting the sample with a bifunctional material that contains an amino group and a carboxyl group and is positively charged at a first pH to allow binding of the nucleic acid to the bifunctional material; and extracting the nucleic acid at a second pH higher than the first pH from the complex.

摘要翻译： 提供了从含有核酸的样品中分离核酸的方法。 该方法包括使样品与含有氨基和羧基的双官能材料接触并在第一pH下带正电荷以允许核酸与双功能材料的结合; 以及从所述络合物中提取比所述第一pH高的第二pH的所述核酸。

公开(公告)号：US20080305011A1

公开(公告)日：2008-12-11

申请号：US11934811

申请日：2007-11-05

申请人： Kyu-youn HWANG ,  Joon-ho Kim ,  Chin-sung Park ,  Sung-young Jeong

发明人： Kyu-youn HWANG ,  Joon-ho Kim ,  Chin-sung Park ,  Sung-young Jeong

IPC分类号： B44C1/22 ,  B01L3/00 ,  G03C5/00

CPC分类号： B01L3/502707 ,  B01L3/502753 ,  B01L2200/12 ,  B01L2300/16 ,  Y10T428/14

摘要： Provided are a microfluidic chip and a method of fabricating the same. The microfluidic chip includes: a lower substrate; an upper substrate formed of a silicone resin, wherein the lower substrate and the upper substrate, bonded together, provide a channel through which a fluid can flow and a chamber to receive the fluid; and an organic thin film formed on the upper surface of the lower substrate except for portions on which the lower substrate and the upper substrate are attached to each other.

摘要翻译： 提供了一种微流控芯片及其制造方法。 微流体芯片包括：下基板; 由硅树脂形成的上基板，其中所述下基板和所述上基板接合在一起，提供流体可以流过的通道和容纳所述流体的室; 以及形成在下基板的上表面上的有机薄膜，除了下基板和上基板彼此附接的部分之外。

公开(公告)号：US20080073214A1

公开(公告)日：2008-03-27

申请号：US11737448

申请日：2007-04-19

申请人： Hun-joo LEE ,  Soo-suk LEE ,  Joon-ho KIM ,  Sung-ouk JUNG ,  In-ho LEE

发明人： Hun-joo LEE ,  Soo-suk LEE ,  Joon-ho KIM ,  Sung-ouk JUNG ,  In-ho LEE

IPC分类号： B01J47/00 ,  C02F1/42 ,  C02F1/469

CPC分类号： B01D61/422 ,  B01D2311/243 ,  B01D2313/02 ,  B01D2313/10 ,  B01D2313/26 ,  B01D2313/30 ,  B01D2313/50 ,  B01D2321/185

摘要： An electrodialysis apparatus includes a sample chamber including first and second dialysis membranes and filled with a sample between the first dialysis membrane and the second dialysis membrane, an anode chamber including an anode and filled with a first chamber solution between the anode and the first dialysis membrane, and a cathode chamber including a cathode and filled with a second chamber solution between the cathode and the second dialysis membrane. In particular, when a voltage is applied to the anode and the cathode, ionic materials of the sample move to the anode and cathode chambers.

摘要翻译： 电渗析装置包括：样品室，包括第一和第二透析膜，并在第一透析膜和第二透析膜之间填充样品;阳极室，包括阳极，并在阳极和第一透析膜之间填充第一室溶液 以及包括阴极并在阴极和第二透析膜之间填充有第二室溶液的阴极室。 特别地，当向阳极和阴极施加电压时，样品的离子材料移动到阳极室和阴极室。

公开(公告)号：US20080044885A1

公开(公告)日：2008-02-21

申请号：US11841117

申请日：2007-08-20

申请人： Kyu-youn HWANG ,  Sung-young JEONG ,  Joon-ho KIM

发明人： Kyu-youn HWANG ,  Sung-young JEONG ,  Joon-ho KIM

IPC分类号： C12N7/02 ,  C12M1/00 ,  C12N1/00 ,  C12N1/14 ,  C12N1/20

CPC分类号： C12N1/02 ,  B01J39/02 ,  B01J39/14

摘要： Provided is a method of separating microorganisms from a sample including contacting the sample containing microorganisms with an inorganic ion exchange material such that the sample reacts with the inorganic ion exchange material, and contacting the reacted sample with a means for capturing microorganisms.

摘要翻译： 提供了从样品中分离微生物的方法，包括使含有微生物的样品与无机离子交换材料接触，使得样品与无机离子交换材料反应，并使反应的样品与捕获微生物的方法接触。

公开(公告)号：US20070138025A1

公开(公告)日：2007-06-21

申请号：US11559196

申请日：2006-11-13

申请人： Hun-joo LEE ,  Joon-ho KIM ,  Kyu-youn HWANG

发明人： Hun-joo LEE ,  Joon-ho KIM ,  Kyu-youn HWANG

IPC分类号： C02F1/461

CPC分类号： G05D21/02

摘要： A microfluidic device includes; an ion exchange membrane, an anode chamber one side of which contacts a surface of the ion exchange membrane, wherein the anode chamber further includes a ladder-shaped anode and an anode support part, and a cathode chamber, one side of which contacts a surface of the ion exchange membrane opposite the anode chamber, wherein the cathode chamber further comprises a cathode, wherein the ladder-shaped anode is formed on a first surface of the anode support part, openings are formed in the anode support part which conform to the shape of the ladder-shaped anode, and a second surface of the anode support part which opposes the first surface of the anode contacts and supports the ion exchange membrane.

摘要翻译： 微流体装置包括： 离子交换膜，阳极室，其一面接触离子交换膜的表面，其中阳极室还包括梯形阳极和阳极支撑部分，阴极室的一侧接触表面 所述阴极室还包括阴极，其中所述梯形阳极形成在所述阳极支撑部分的第一表面上，所述阳极支撑部分形成符合所述形状的阳极支撑部分的形状， 并且与阳极的第一表面相对的阳极支撑部分的第二表面接触并支撑离子交换膜。