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    Devices and methods for occlusion of the uterine arteries
    53.
    发明授权
    Devices and methods for occlusion of the uterine arteries 失效
    用于闭塞子宫动脉的装置和方法

    公开(公告)号：US06764488B1

    公开(公告)日：2004-07-20

    申请号：US09550908

    申请日：2000-04-17

    申请人： Fred Burbank ,  Michael Jones ,  Paul Lubock

    发明人： Fred Burbank ,  Michael Jones ,  Paul Lubock

    IPC分类号： A61B1818

    CPC分类号： A61B8/12 ,  A61B8/06 ,  A61B8/0833 ,  A61B17/12013 ,  A61B17/42 ,  A61B18/1485

    摘要： Devices and methods are disclosed for treating a uterine disorder which receive its blood supply from a uterine artery. In particular, uterine fibroids are effectively treated by occluding the uterine arteries using trans-vaginal, trans-uterine, transrectal, or retroperitoneal approaches. The devices and methods are advantageous because the inventive procedures may be performed by a patient's gynecologist in the course of treatment, avoiding the need for referrals to specialist practitioners and for more radical treatments, such as hysterectomies. The methods include both temporary and permanent occlusion of the arteries. A cannula carries an imaging device and a member which will easily penetrate tissue, the member including a device which partially or completely, and temporarily or permanently, occludes a uterine artery.

    摘要翻译： 公开了用于治疗从子宫动脉接受其血液供应的子宫疾病的装置和方法。 特别地，子宫肌瘤通过使用经阴道，经子宫，经直肠或腹膜后方法闭塞子宫动脉来有效治疗。 所述装置和方法是有利的，因为本发明的方法可以由患者的妇科医生在治疗过程中进行，避免需要转诊给专科医师，以及进行诸如子宫切除术等更激进的治疗。 这些方法包括动脉的临时和永久闭塞。 套管携带成像装置和容易穿透组织的构件，该构件包括部分地或完全地暂时地或永久地阻塞子宫动脉的装置。

    Device and methods for occlusion of the uterine artieries
    54.
    发明授权
    Device and methods for occlusion of the uterine artieries 失效
    用于闭塞子宫手术的装置和方法

    公开(公告)号：US06602251B2

    公开(公告)日：2003-08-05

    申请号：US09835402

    申请日：2001-04-17

    申请人： Fred Burbank ,  Michael Jones ,  Paul Lubock

    发明人： Fred Burbank ,  Michael Jones ,  Paul Lubock

    IPC分类号： A61B1818

    CPC分类号： A61B8/12 ,  A61B8/06 ,  A61B8/0833 ,  A61B17/12013 ,  A61B17/42 ,  A61B18/1485

    摘要： Devices and methods are disclosed for treating a uterine disorder which receive its blood supply from a uterine artery. In particular, uterine fibroids are effectively treated by occluding the uterine arteries using trans-vaginal, trans-uterine, transrectal, or retroperitoneal approaches. The devices and methods are advantageous because the inventive procedures may be performed by a patient's gynecologist in the course of treatment, avoiding the need for referrals to specialist practitioners and for more radical treatments, such as hysterectomies. The methods include both temporary and permanent occlusion of the arteries. A cannula carries an imaging device and a member which will easily penetrate tissue, the member including a device which partially or completely, and temporarily or permanently, occludes a uterine artery.

    摘要翻译： 公开了用于治疗从子宫动脉接受其血液供应的子宫疾病的装置和方法。 特别地，子宫肌瘤通过使用经阴道，经子宫，经直肠或腹膜后方法闭塞子宫动脉来有效治疗。 所述装置和方法是有利的，因为本发明的方法可以由患者的妇科医生在治疗过程中进行，避免需要转诊给专科医师，以及进行诸如子宫切除术等更激进的治疗。 这些方法包括动脉的临时和永久闭塞。 套管携带成像装置和容易穿透组织的构件，该构件包括部分地或完全地暂时地或永久地阻塞子宫动脉的装置。

    Marker or filler forming fluid
    56.
    发明授权
    Marker or filler forming fluid 有权

    公开(公告)号：US10299881B2

    公开(公告)日：2019-05-28

    申请号：US12214947

    申请日：2008-06-24

    申请人： Fred H. Burbank ,  Michael L. Jones ,  Frank Louw ,  Paul Lubock

    发明人： Fred H. Burbank ,  Michael L. Jones ,  Frank Louw ,  Paul Lubock

    IPC分类号： A61B90/00 ,  A61K49/22

    摘要： A solution for forming a marker or filler mass for an intracorporeal site. The solution contains a polar, water soluble non-aqueous solvent such as dimethyl sulfoxide and a bioabsorbable, essentially water insoluble polymer such as polylactic acid, or copolymers of lactic acid and glycolic acid. The solution may be delivered to the biopsy site by a suitable syringe and delivery tube. The delivery tube is preferably provided with a releasable radiopaque element on the distal tip which can be released within the polymeric marker mass formed in the biopsy cavity.

    Tissue site markers for in vivo imaging
    57.
    发明授权
    Tissue site markers for in vivo imaging 有权
    用于体内成像的组织位点标记

    公开(公告)号：US08224424B2

    公开(公告)日：2012-07-17

    申请号：US12460052

    申请日：2009-07-13

    申请人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    发明人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    IPC分类号： A61B5/00 ,  A61B6/00 ,  A61B19/00

    CPC分类号： A61M37/0069 ,  A61B6/12 ,  A61B8/0833 ,  A61B10/02 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/222

    摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

    摘要翻译： 本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后标记的组织被移动或操纵时抵抗从活检腔的迁移。

    Marker or filler forming fluid
    58.
    发明授权
    Marker or filler forming fluid 有权
    标记或填料成型液

    公开(公告)号：US07877133B2

    公开(公告)日：2011-01-25

    申请号：US10444428

    申请日：2003-05-23

    申请人： Fred H. Burbank ,  Michael L. Jones ,  Frank Louw ,  Paul Lubock

    发明人： Fred H. Burbank ,  Michael L. Jones ,  Frank Louw ,  Paul Lubock

    IPC分类号： A61B6/00 ,  A61B10/00

    CPC分类号： A61B90/39 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3933 ,  A61B2090/3987 ,  A61K49/226

    摘要： A solution for forming a marker or filler mass for an intracorporeal site. The solution contains a polar, water soluble non-aqueous solvent such as dimethyl sulfoxide and a bioabsorbable, essentially water insoluble polymer such as polylactic acid, or copolymers of lactic acid and glycolic acid. The solution may be delivered to the biopsy site by a suitable syringe and delivery tube. The delivery tube is preferably provided with a releasable radiopaque element on the distal tip which can be released within the polymeric marker mass formed in the biopsy cavity.

    摘要翻译： 用于形成体内部位的标记物或填充剂块的溶液。 该溶液含有极性的水溶性非水溶剂如二甲基亚砜和生物可吸收的，基本上不溶于水的聚合物如聚乳酸，或乳酸和乙醇酸的共聚物。 溶液可以通过合适的注射器和输送管递送到活检部位。 输送管优选地设置在远端上的可释放的不透射线元件，其可以在形成于活检腔内的聚合物标记块内释放。

    Tissue cutting member for a biopsy device
    59.
    发明申请
    Tissue cutting member for a biopsy device 有权

    公开(公告)号：US20060276723A1

    公开(公告)日：2006-12-07

    申请号：US11438955

    申请日：2006-05-22

    申请人： Paul Lubock ,  Frank Louw ,  Richard Quick

    发明人： Paul Lubock ,  Frank Louw ,  Richard Quick

    IPC分类号： A61B10/00

    CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B17/320016 ,  A61B17/3417

    摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.