Fodder additive and a process for the preparation
    52.
    发明授权
    Fodder additive and a process for the preparation 失效
    饲料添加剂和制备方法

    公开(公告)号:US4659712A

    公开(公告)日:1987-04-21

    申请号:US790856

    申请日:1985-10-24

    CPC分类号: A23K50/30 A23K20/111

    摘要: The invention relates to fodder additives comprising a compound inducing the microsomal enzyme system of the liver, preferably a compound of the formula (I) ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are identical or different and stand for hydrogen, halogen, trihalomethyl, or alkyl or alkoxy each containing from 1 to 6 carbon atoms;R.sub.4 is phenyl, dialkylaminocarbonyl or alkoxycarbonyl having from 1 to 6 carbon atoms in the alkyl and alkoxy moieties, respectively;R.sub.5 is hydrogen or methyl, or together with R.sub.4 and the adjacent nitrogen atom forms a hetero-ring having up to 8 members;n is 1, 2, 3, 4 or 5;m is 0 or 1;a is 0 or 1,with the proviso that if a=0, R.sub.1 is trihalomethyl and R.sub.2 and R.sub.3 both are hydrogen, preferably in amount of 0.5 to 99% by weight, in an admixture with conventional carriers and/or additives and optionally at least one further active ingredient conventionally used in the animal husbandry.The enzyme inducing compounds used according to the invention accelerate the elimination of various xenobiotics metabolizing in the liver.

    摘要翻译: 本发明涉及包含诱导肝脏微粒体酶系统的化合物的饲料添加剂,优选式(I)化合物其中R 1,R 2和R 3相同或不同,代表氢,卤素, 三卤甲基或各自含有1至6个碳原子的烷基或烷氧基; R4分别是苯基,二烷基氨基羰基或在烷基和烷氧基部分具有1-6个碳原子的烷氧基羰基; R 5是氢或甲基,或与R 4一起并且相邻的氮原子形成具有至多8个成员的杂环; n为1,2,3,4或5; m为0或1; a为0或1,条件是如果a = 0,则R1为三卤甲基,R2和R3均为氢,优选为0.5至99重量%,与常规载体和/或添加剂混合,并且任选地 至少一种常规用于畜牧业的活性成分。 根据本发明使用的酶诱导化合物加速了在肝脏中代谢的各种异种生物的消除。