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公开(公告)号：US06808513B2
公开(公告)日：2004-10-26
申请号：US10166848
申请日：2002-06-10
IPC分类号： A61M5315
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2005/14553 , A61M2205/581 , A61M2205/582 , A61M2205/583 , Y10S128/01
摘要： A front-loading syringe, which comprises a movable plunger for injecting liquid contrast media, is mountable on a front wall of an injector housing having a pressure jacket, by a first quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An injection end of the syringe may include loop-shaped reinforcing handle portions.
摘要翻译： 包括用于注射液体造影剂的可移动柱塞的前装载注射器可通过第一快速释放机构安装在具有压力套的注射器壳体的前壁上。 同时，柱塞通过第二容易释放的机构连接到喷射器驱动机构。 在安装操作期间，传感器从注射器上的指示器装置读取注射信息并将其馈送到注射器控制器。 注射器的注射端可以包括环形加强手柄部分。
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52.发明授权公开(公告)号：US06733478B2
公开(公告)日：2004-05-11
申请号：US10287167
申请日：2002-11-04
IPC分类号： A61M500
CPC分类号： A61M5/14546 , A61M5/14566 , A61M2005/14553 , A61M2205/581 , A61M2205/582 , A61M2205/583 , Y10S128/01
摘要： A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs, which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background. An injection end of the syringe comprises an injector portion of reduced diameter inside a screw-threaded attachment portion of larger diameter, and may include loop-shaped reinforcing handle portions.
摘要翻译： 一种包括用于注射液体造影剂的活动柱塞的前装载注射器，可旋转地安装在喷射器壳体的前壁上，其具有过盈配合并且与其相关的密封关系，具有或不具有压力套， 快速释放机制。 同时，柱塞通过第二容易释放的机构连接到喷射器驱动机构。 在安装操作期间，传感器从注射器上的指示器装置读取注射信息并将其馈送到注射器控制器。 当注射器基本上处于所需的安装位置时，也可以触发听觉和触觉指示机构。 注射器可以包括也用作体积灰度的加强肋，以及液体介质的存在或不存在，指示针对液体介质背景呈圆形并且与空气背景呈椭圆形的点。 注射器的注射端部包括在较大直径的螺纹连接部分内的直径减小的注射器部分，并且可以包括环形加强手柄部分。
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公开(公告)号：US5795333A
公开(公告)日：1998-08-18
申请号：US375431
申请日：1995-01-19
CPC分类号： A61M5/14546 , A61M2005/14553 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M5/14566 , Y10S128/01
摘要： A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background. An injection end of the syringe comprises an injector portion of reduced diameter inside a screw-threaded attachment portion of larger diameter, and may include loop-shaped reinforcing handle portions.
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公开(公告)号：US5741232A
公开(公告)日：1998-04-21
申请号：US780012
申请日：1996-12-23
CPC分类号： A61M5/14546 , A61M2005/14553 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M5/14566 , Y10S128/01
摘要： A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background. An injection end of the syringe comprises an injector portion of reduced diameter inside a screw-threaded attachment portion of larger diameter, and may include loop-shaped reinforcing handle portions.
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55.发明授权公开(公告)号：US07204797B2
公开(公告)日：2007-04-17
申请号：US10893591
申请日：2004-07-16
IPC分类号： A61N5/00
CPC分类号： A61K51/1282 , A61M5/007 , A61M5/1407 , A61M5/1452 , A61M5/14546 , A61M5/1785 , G06F19/00 , G16H20/17
摘要： A method of dispensing a hazardous pharmaceutical comprising the steps of: connecting a source of flushing fluid to a first port of a fluid delivery set; connecting a pressurizing unit of a powered injector system (including a powered injector and the pressurizing unit) to a second port of the fluid delivery set; purging air from the fluid delivery set; and, after purging air from the fluid delivery set, connecting a third port of the fluid delivery set to a source of the hazardous pharmaceutical. The fluid delivery set can, for example, include a valve system or assembly to control flow of fluid through the fluid delivery set. A system for delivery of a hazardous pharmaceutical includes: a syringe in operative connection with a powered injector; a protective container to enclose the syringe during operation thereof; the protective container being adapted to protect personnel from detrimental effects of the pharmaceutical; at least one source of flushing fluid; a fluid path adapted to connect to a patient; at least one source of the pharmaceutical; and a fluid delivery set including a valve assembly to which the syringe, the source of flushing fluid, the fluid path and the source of pharmaceutical are removably connectable. The valve assembly provides flow control through the fluid delivery set such that operator contact with the fluid delivery set is not required after connection of the source of pharmaceutical to the fluid delivery set.
摘要翻译： 一种分配危险药物的方法，包括以下步骤：将冲洗流体源连接到流体输送装置的第一端口; 将动力注射器系统（包括动力注射器和加压单元）的加压单元连接到流体输送组的第二端口; 从流体输送装置吹扫空气; 并且在从流体输送装置吹扫空气之后，将流体输送装置的第三端口连接到危险药物源。 流体输送装置可以例如包括阀系统或组件以控制通过流体输送组的流体的流动。 用于递送危险药物的系统包括：与动力注射器可操作地连接的注射器; 在操作期间包围注射器的保护容器; 保护容器适于保护人员免受药物的不利影响; 至少一个冲洗液源; 适于连接到患者的流体路径; 至少一种药物来源; 以及包括阀组件的流体输送组件，注射器，冲洗流体源，流体路径和药物源可拆卸地连接到该组件。 阀组件通过流体输送组件提供流量控制，使得在将药物源连接到流体输送装置之后，操作者不需要与流体输送装置接触。
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56.发明授权Injection system, pump system for use therein and method of use of pumping system 有权注射系统，其中使用的泵系统和泵送系统的使用方法公开(公告)号：US06197000B1
公开(公告)日：2001-03-06
申请号：US09290451
申请日：1999-04-13
申请人： David M. Reilly , Alan D. Hirschman
发明人： David M. Reilly , Alan D. Hirschman
IPC分类号： A61M500
CPC分类号： A61M5/16827 , A61M2206/22
摘要： The present invention provides an injection system and a pump system for use therein for pressurizing a liquid medium for injection into a patient. In general, the pump system comprises a pressurizing unit having at least one chamber. Each chamber has disposed therein a pressurizing mechanism to pressurize liquid medium within the chamber. Preferably, the pressurizing mechanism positively displaces the liquid medium through generally linear motion of the pressurizing mechanism within the chamber. Through reciprocating linear motion of the pressurizing mechanism (for example, a piston), the liquid medium is alternatively drawn into the chamber from a source of liquid medium (for example, a container) and forced out of the chamber under a desired pressure. Each chamber comprises an inlet port and an outlet port. The pump system also preferably comprises an inlet port check valve which allows the liquid medium to flow into the chamber through the inlet port, but substantially prevents the liquid medium from flowing out of the chamber through the inlet port. Likewise, the pump system preferably comprises an outlet port check valve which allows pressurized liquid medium to flow out of the chamber through the outlet port, but substantially prevents the liquid medium from flowing into the chamber through the outlet port. Each inlet port is connected to a source of liquid medium. Each outlet port is connected to a common outlet line or channel leading to the patient.
摘要翻译： 本发明提供一种注射系统和用于其中的用于将注射到患者体内的液体介质加压的泵系统。 通常，泵系统包括具有至少一个室的加压单元。 每个室都设置有加压机构以对腔室内的液体介质加压。 优选地，加压机构通过腔室内的加压机构的大致线性运动来使液体介质正向移位。 通过加压机构（例如，活塞）的往复直线运动，液体介质被替代地从液体介质（例如，容器）的源拉入室中，并在期望的压力下被迫离开室。 每个室包括入口和出口。 泵系统还优选地包括入口端口止回阀，其允许液体介质通过入口端口流入室中，但是基本上防止液体介质通过入口端口流出室。 类似地，泵系统优选地包括出口端口止回阀，其允许加压液体介质通过出口端口流出室，但是基本上防止液体介质通过出口端口流入室中。 每个入口连接到液体介质源。 每个出口端口连接到通向病人的公共出口管线或通道。
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57.发明授权Injection system, pump system for use therein and method of use of pumping system 失效注射系统，其中使用的泵系统和泵送系统的使用方法
公开(公告)号：US5916197A
公开(公告)日：1999-06-29
申请号：US801706
申请日：1997-02-14
申请人： David M. Reilly , Alan D. Hirschman
发明人： David M. Reilly , Alan D. Hirschman
CPC分类号： A61M5/16827 , A61M2206/22
摘要： The present invention provides an injection system and a pump system for use therein for pressurizing a liquid medium for injection into a patient. In general, the pump system comprises a pressurizing unit having at least one chamber. Each chamber has disposed therein a pressurizing mechanism to pressurize liquid medium within the chamber. Preferably, the pressurizing mechanism positively displaces the liquid medium through generally linear motion of the pressurizing mechanism within the chamber. Through reciprocating linear motion of the pressurizing mechanism (for example, a piston), the liquid medium is alternatively drawn into the chamber from a source of liquid medium (for example, a container) and forced out of the chamber under a desired pressure. Each chamber comprises an inlet port and an outlet port. The pump system also preferably comprises an inlet port check valve which allows the liquid medium to flow into the chamber through the inlet port, but substantially prevents the liquid medium from flowing out of the chamber through the inlet port. Likewise, the pump system preferably comprises an outlet port check valve which allows pressurized liquid medium to flow out of the chamber through the outlet port, but substantially prevents the liquid medium from flowing into the chamber through the outlet port. Each inlet port is connected to a source of liquid medium. Each outlet port is connected to a common outlet line or channel leading to the patient.
摘要翻译： 本发明提供一种注射系统和用于其中的用于将注射到患者体内的液体介质加压的泵系统。 通常，泵系统包括具有至少一个室的加压单元。 每个室都设置有加压机构以对腔室内的液体介质加压。 优选地，加压机构通过腔室内的加压机构的大致线性运动来使液体介质正向移位。 通过加压机构（例如，活塞）的往复直线运动，液体介质被替代地从液体介质（例如，容器）的源拉入室中，并在期望的压力下被迫离开室。 每个室包括入口和出口。 泵系统还优选地包括入口端口止回阀，其允许液体介质通过入口端口流入室中，但是基本上防止液体介质通过入口端口流出室。 类似地，泵系统优选地包括出口端口止回阀，其允许加压液体介质通过出口端口流出室，但是基本上防止液体介质通过出口端口流入室中。 每个入口连接到液体介质源。 每个出口端口连接到通向病人的公共出口管线或通道。
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58.再颁专利公开(公告)号：USRE45717E1
公开(公告)日：2015-10-06
申请号：US14261028
申请日：2014-04-24
CPC分类号： A61M5/16827 , A61M5/007 , A61M5/1422
摘要： A system and method for mixing and delivering fluids such as contrast media and saline is disclosed including at least two fluid sources, a pump, a joining fluid path for connecting the at least two fluid sources to an inlet to of the pump, and a valve device in the fluid path upstream of the pump. The valve device includes an actuator adapted to restrict flow in at least one of the respective fluid lines connecting the at least two fluid sources to the pump inlet. A patient interface device may be associated with an outlet of the pump. The valve device actuator is generally adapted to restrict the flow in at least one of the respective fluid lines such that a positional change in valve device actuator position provides a change in fluid mixture ratio of the fluids from the at least two fluid sources to the pump inlet.
摘要翻译： 公开了用于混合和输送诸如造影剂和盐水的流体的系统和方法，包括至少两个流体源，泵，用于将至少两个流体源连接到泵的入口的连接流体路径，以及阀 在泵的上游的流体路径中的装置。 阀装置包括致动器，其适于限制将至少两个流体源连接到泵入口的相应流体管线中的至少一个中的流动。 患者接口装置可以与泵的出口相关联。 阀装置致动器通常适于限制相应流体管线中的至少一个中的流动，使得阀装置致动器位置的位置变化提供了流体从至少两个流体源到泵的流体混合比的变化 进口。
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公开(公告)号：US6042565A
公开(公告)日：2000-03-28
申请号：US731341
申请日：1996-10-18
申请人： Alan D. Hirschman , David M. Reilly
发明人： Alan D. Hirschman , David M. Reilly
CPC分类号： A61M5/14546 , A61M2005/14573 , A61M5/1456 , A61M5/1458 , A61M5/31511
摘要： The present invention provides a syringe and a powered injector for use therewith in which the syringe is attachable to a powered drive member of an injector over a range of relative axial positions of the syringe plunger and the drive member. The syringe comprises a plunger, and a plunger extension connected thereto and extending rearward from the plunger, such that the syringe may be operated manually or by a powered injector. In one embodiment, the plunger extension comprises a plurality of plunger attachment members located over a range of axial positions on the plunger extension. Each of the plurality of plunger attachment members is adapted to form a releasable attachment with at least one cooperating injector attachment member on the powered drive member. In another embodiment, the plunger extension of the plunger comprises at least one plunger attachment member which is adapted to form a releasable attachment with each of a plurality of corresponding injector attachment members located over a range of axial positions on the powered drive member. By providing a plurality of cooperating attachment members over a range of axial positions on at least one of the plunger extension or the powered drive member, operative attachment of the plunger and the drive member is made possible at multiple axial positions of the plunger (within the syringe) for each axial position of the drive member over at least a range of possible plunger axial positions. Attachment of the plunger to the drive member at various axial positions of the plunger thus becomes an easier task than previously possible with current powered injector systems.
摘要翻译： 本发明提供了一种注射器和用于其的动力注射器，其中注射器可在注射器柱塞和驱动构件的相对轴向位置的范围内附接到注射器的动力驱动构件。 注射器包括柱塞和连接到其上并从柱塞向后延伸的柱塞延伸部，使得注射器可以手动操作或通过动力注射器操作。 在一个实施例中，柱塞延伸部包括位于柱塞延伸部上的轴向位置范围上的多个柱塞附接构件。 多个柱塞附接构件中的每一个适于在动力驱动构件上形成具有至少一个配合的喷射器附接构件的可释放附件。 在另一个实施例中，柱塞的柱塞延伸部包括至少一个柱塞附接构件，其适于形成可释放的附件，其中多个对应的喷射器附接构件中的每一个位于动力驱动构件上的轴向位置的范围上。 通过在柱塞延伸部或动力驱动部件中的至少一个上的一定范围的轴向位置设置多个配合的附接部件，可以在柱塞的多个轴向位置 注射器），用于驱动构件的每个轴向位置在可能的柱塞轴向位置的至少一个范围上。 因此，柱塞在柱塞的各个轴向位置处附接到驱动构件成为比以前可能的当前动力喷射器系统更容易的任务。
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公开(公告)号：US4854324A
公开(公告)日：1989-08-08
申请号：US161434
申请日：1988-02-24
申请人： Alan D. Hirschman , David M. Reilly , Ross H. Potter , John A. Stulen , Eric M. Toft , John G. Clark
发明人： Alan D. Hirschman , David M. Reilly , Ross H. Potter , John A. Stulen , Eric M. Toft , John G. Clark
IPC分类号： A61M5/172
CPC分类号： A61M5/14546 , A61M5/172 , A61M2230/04 , Y10S128/01
摘要： An angiographic injector device for use in x-ray photography for delivering contrast media to a patient at controlled rates and pressures. A processor elicits injection parameters from an operator or a pre-programmed injection module, and on the basis of the injection parameters, calculates appropriate control signals for use in a closed-loop servo system to actuate the plunger of a syringe containing the contrast media. Injection parameters includes flow rate, volume, duration, pressure limit and rise-fall time of flow rate. The device also includes control circuits for inhibiting the injection device in response to a contrast media pressure limit, failure in the processor or injection control system, or upon reaching a predetermined volume of injected media. A mechanical stop member cooperates with the control circuit for blocking movement of the syringe plunger upon reaching the predetermined injected volume. Further, the device includes a self-test feature for checking the status of operational components thereof and a self-calibration feature for calibrating the servo system and position monitors. To improve reliability and to provide immunity from data corruption due to line power interruption, injection parameters are stored in battery-powered primary and secondary memories, and are compared and verified prior to an injection. To assist in coordinating an injection in synchronism with cardiac activity, the device monitors the ECG waveform of the patient's heart and injects a small bolus of contrast media at a given interval, such as the distolic interval. An interface also is provided for providing remote transfer of status and control information with the angiographic injector device.
摘要翻译： 一种用于x射线摄影的血管造影注射器装置，用于以受控的速率和压力向患者输送造影剂。 处理器从操作者或预编程的注射模块引出注射参数，并且基于注射参数，计算用于闭环伺服系统中的合适的控制信号以致动含有造影剂的注射器的柱塞。 注射参数包括流量，体积，持续时间，压力极限和流速上升时间。 该装置还包括用于响应于造影剂压力极限，处理器或注射控制系统中的故障或达到预定体积的注射介质而抑制注射装置的控制电路。 机械止动构件与控制电路配合，以阻止注射器柱塞达到预定注射体积时的运动。 此外，该装置包括用于检查其操作部件的状态的自检特征和用于校准伺服系统和位置监视器的自校准特征。 为了提高可靠性并提供由于线路电源中断引起的数据损坏的免疫力，注入参数存储在电池供电的初级和次级存储器中，并在注入之前进行比较和验证。 为了协调与心脏活动同步的注射，该装置监测患者心脏的心电图波形，并以给定的时间间隔（例如恶心间隔）注入小量的造影剂。 还提供了用于提供与血管造影注射器装置的状态和控制信息的远程传送的界面。
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