公开(公告)号：US20080154115A1

公开(公告)日：2008-06-26

申请号：US10597762

申请日：2005-02-03

申请人： Miha Fuderer ,  Holger Eggers

发明人： Miha Fuderer ,  Holger Eggers

IPC分类号： A61B5/055

CPC分类号： G01R33/5611

摘要： A novel magnetic resonance imaging method and apparatus is described wherein an image is derived from sub-sampled magnetic resonance signals and on the basis of the spatial sensitivity profile of each receiving antenna. A sequence of RF-pulses and gradients is applied, which sequence corresponds to a set of trajectories containing at least one substantially non-linear trajectory in k-space, wherein the density of said trajectory set being substantially lower than the density corresponding to the object size. Each signal along said trajectory set is sampled at least at two different receiver antenna positions. The image is reconstructed by converting the data of said signals to a Cartesian grid by convolution with a gridding kernel, whereby the gridding kernel is specific for each antenna, differs between one region and another in k-space, and is a Fourier-transform of a pattern weighted for each antenna with respect to the Cartesian grid.

摘要翻译： 描述了一种新颖的磁共振成像方法和装置，其中根据次采样的磁共振信号并基于每个接收天线的空间灵敏度分布导出图像。 应用RF脉冲和梯度的序列，该序列对应于在k空间中包含至少一个基本非线性轨迹的一组轨迹，其中所述轨迹集的密度基本上低于对应于物体的密度 尺寸。 至少在两个不同的接收机天线位置对沿着所述轨迹组的每个信号进行采样。 通过与网格内核卷积将所述信号的数据转换为笛卡尔网格来重建图像，由此网格核对于每个天线是特定的，在k空间中在一个区域和另一个区域之间是不同的，并且是傅里叶变换 对于每个天线相对于笛卡尔网格加权的图案。

公开(公告)号：US07358731B2

公开(公告)日：2008-04-15

申请号：US10569193

申请日：2004-08-09

申请人： Miha Fuderer ,  Robert Paul Kleihorst

发明人： Miha Fuderer ,  Robert Paul Kleihorst

IPC分类号： G01V3/00

CPC分类号： G01R33/246 ,  G01R33/3415 ,  G01R33/5611 ,  G01R33/5659

摘要： The invention relates to a method for determination of spatial sensitivity profiles of RF transmit and/or receive coils (7, 8, 9) in an examination volume (17) of a magnetic resonance (MR) imaging device (1). In accordance with the method of the invention, nuclear magnetization is excited within the examination volume (17) by a sequence of RF pulses and switched magnetic field gradients, wherein the sequence comprises RF pulses with at least two different excitation flip angles. MR signals are acquired and processed so as to form at least two MR images, each corresponding to one of these flip angles. The spatial sensitivity profiles are then computed in the positions of the pixels or voxels of the MR images based upon the dependence of the pixel or voxel values on the respective flip angles. Alternatively, a plurality of instances of a sequence of RF pulses and switched magnetic field gradients is applied and MR signals are acquired, wherein a different combination of transmit and receive coils (7, 8, 9) is used for each instance of the sequence. The spatial sensitivity profiles are then computed in the positions of the pixels or voxels of the MR images formed from the acquired MR signals by taking the logarithm of the pixel or voxel values and by solving a linear system of equations for each pixel or voxel.

摘要翻译： 本发明涉及一种用于确定在磁共振（MR）成像装置（1）的检查体积（17）中的RF发射和/或接收线圈（7,8,9）的空间灵敏度分布的方法。 根据本发明的方法，通过一系列RF脉冲和切换的磁场梯度，在检查体积（17）内激发核磁化，其中该序列包括具有至少两个不同激发翻转角的RF脉冲。 获取并处理MR信号以形成至少两个MR图像，每个MR图像对应于这些翻转角之一。 然后基于像素或体元值对相应翻转角的依赖性，在MR图像的像素或体素的位置中计算空间灵敏度分布。 或者，施加RF脉冲序列和切换磁场梯度的多个实例，并获取MR信号，其中发射和接收线圈（7,8,9）的不同组合用于序列的每个实例。 然后，通过采取像素或体元值的对数，并通过求解每个像素或体素的线性方程组，在由所获取的MR信号形成的MR图像的像素或体素的位置中计算空间灵敏度分布。

公开(公告)号：US20070182412A1

公开(公告)日：2007-08-09

申请号：US10597060

申请日：2005-01-05

申请人： Ulrich Katscher ,  Johan Van Den Brink ,  Miha Fuderer

发明人： Ulrich Katscher ,  Johan Van Den Brink ,  Miha Fuderer

IPC分类号： G01V3/00

CPC分类号： G01R33/4824 ,  G01R33/5608 ,  G01R33/5611

摘要： A magnetic resonance imaging apparatus includes a plurality of radio frequency coils (34) that acquire variable density sensitivity encoded data that is undersampled at least away from the center of k-space. A reconstruction processor (52) for each coil reconstructs: a regularization image reconstructed from a higher density portion of the variable density sensitivity encoded data disposed at or near a center of k-space acquired by that coil; and a folded image reconstructed from the variable density sensitivity encoded data acquired by that coil. An unfolding processor (66) unfolds the folded images. The unfolding is regularized by the regularization images.

摘要翻译： 磁共振成像设备包括多个射频线圈（34），其获取至少远离k空间中心的欠采样的可变密度灵敏度编码数据。 每个线圈的重建处理器（52）重建：从由该线圈获取的k空间的中心处或附近的可变密度灵敏度编码数据的较高密度部分重建的正则化图像; 以及从由该线圈获取的可变密度灵敏度编码数据重建的折叠图像。 展开处理器（66）展开折叠的图像。 正规化图像正规化展开。

公开(公告)号：US07218107B2

公开(公告)日：2007-05-15

申请号：US10570076

申请日：2004-08-30

申请人： Miha Fuderer

发明人： Miha Fuderer

IPC分类号： G01V3/00

CPC分类号： G01R33/565 ,  G06T5/006

摘要： An apparatus for producing a corrected reconstructed image from magnetic resonance imaging data acquired by a magnetic resonance imaging scanner (10) includes a reconstruction processor (44) that reconstructs a corrected reconstructed image from acquired magnetic resonance imaging data. A parameters calculation processor (52) determines at least one characteristic of the imaging subject. A correction pattern adjustment processor (54) selects a correction pattern from a family of stored correction patterns based on the at least one characteristic. An image correction processor (56) corrects the uncorrected reconstructed image using the selected correction pattern to produce the corrected reconstructed image.

公开(公告)号：US20070024281A1

公开(公告)日：2007-02-01

申请号：US10570076

申请日：2004-08-30

申请人： Miha Fuderer

发明人： Miha Fuderer

IPC分类号： G01V3/00

CPC分类号： G01R33/565 ,  G06T5/006

摘要： An apparatus for producing a corrected reconstructed image from magnetic resonance imaging data acquired by a magnetic resonance imaging scanner (10) includes a reconstruction processor (44) that reconstructs a corrected reconstructed image from acquired magnetic resonance imaging data. A parameters calculation processor (52) determines at least one characteristic of the imaging subject. A correction pattern adjustment processor (54) selects a correction pattern from a family of stored correction patterns based on the at least one characteristic. An image correction processor (56) corrects the uncorrected reconstructed image using the selected correction pattern to produce the corrected reconstructed image.

摘要翻译： 一种用于由磁共振成像扫描器（10）获取的磁共振成像数据产生校正后的重建图像的装置，包括从所获取的磁共振成像数据重建校正后的重建图像的重建处理器（44）。 参数计算处理器（52）确定成像对象的至少一个特性。 校正图案调整处理器（54）基于至少一个特性从存储的校正图案系列中选择校正图案。 图像校正处理器（56）使用所选择的校正图案校正未校正的重建图像，以产生校正的重建图像。

公开(公告)号：US20060261809A1

公开(公告)日：2006-11-23

申请号：US10569193

申请日：2004-08-09

申请人： Miha Fuderer ,  Robert Kleihorst

发明人： Miha Fuderer ,  Robert Kleihorst

IPC分类号： G01V3/00

CPC分类号： G01R33/246 ,  G01R33/3415 ,  G01R33/5611 ,  G01R33/5659

摘要： The invention relates to a method for determination of spatial sensitivity profiles of RF transmit and/or receive coils (7, 8, 9) in an examination volume (17) of a magnetic resonance (MR) imaging device (1). In accordance with the method of the invention, nuclear magnetization is excited within the examination volume (17) by a sequence of RF pulses and switched magnetic field gradients, wherein the sequence comprises RF pulses with at least two different excitation flip angles. MR signals are acquired and processed so as to form at least two MR images, each corresponding to one of these flip angles. The spatial sensitivity profiles are then computed in the positions of the pixels or voxels of the MR images based upon the dependence of the pixel or voxel values on the respective flip angles. Alternatively, a plurality of instances of a sequence of RF pulses and switched magnetic field gradients is applied and MR signals are acquired, wherein a different combination of transmit and receive coils (7, 8, 9) is used for each instance of the sequence. The spatial sensitivity profiles are then computed in the positions of the pixels or voxels of the MR images formed from the acquired MR signals by taking the logarithm of the pixel or voxel values and by solving a linear system of equations for each pixel or voxel.

摘要翻译： 本发明涉及一种用于确定在磁共振（MR）成像装置（1）的检查体积（17）中的RF发射和/或接收线圈（7,8,9）的空间灵敏度分布的方法。 根据本发明的方法，通过一系列RF脉冲和切换的磁场梯度，在检查体积（17）内激发核磁化，其中该序列包括具有至少两个不同激发翻转角的RF脉冲。 获取并处理MR信号以形成至少两个MR图像，每个MR图像对应于这些翻转角之一。 然后基于像素或体元值对相应翻转角的依赖性，在MR图像的像素或体素的位置中计算空间灵敏度分布。 或者，施加RF脉冲序列和切换磁场梯度的多个实例，并获取MR信号，其中发射和接收线圈（7,8,9）的不同组合用于序列的每个实例。 然后，通过采取像素或体元值的对数，并通过求解每个像素或体素的线性方程组，在由所获取的MR信号形成的MR图像的像素或体素的位置中计算空间灵敏度分布。

公开(公告)号：US20060061359A1

公开(公告)日：2006-03-23

申请号：US10542828

申请日：2003-12-15

申请人： Miha Fuderer

发明人： Miha Fuderer

IPC分类号： G01V3/00

CPC分类号： G01R33/56518 ,  G01R33/5611 ,  G01R33/56563

摘要： A magnetic resonance imaging method is presented for forming an image of an object, wherein a stationary magnetic field and temporary magnetic fields having a position dependent field pattern are applied, magnetic resonance signals are acquired by at least one receiver antenna, spins are excitated in a part of the object, MR signals are acquired during application of the position-dependent field patterns (G1, G2, . . . ) and a magnetic resonance image is derived from the sampled magnetic resonance signals. The field patterns are substantially non-linear, the number N of total field patterns is larger than 3, and at least N−1 field patterns are independently controllable in field strength. The magnetic resonance signals are acquired in a sub-sampling fashion.

摘要翻译： 提出了用于形成物体的图像的磁共振成像方法，其中施加具有位置相关磁场图案的固定磁场和临时磁场，通过至少一个接收器天线获取磁共振信号，旋转在 在对象的一部分中，在应用位置相关的场模式（G 1，N 2，...，...）期间获取MR信号，并导出磁共振图像 从采样磁共振信号。 场图案基本上是非线性的，总场图案的数量N大于3，并且至少N-1场图案在场强中是独立可控的。 以次采样的方式获取磁共振信号。

公开(公告)号：US06552540B2

公开(公告)日：2003-04-22

申请号：US09734776

申请日：2000-12-12

申请人： Miha Fuderer

发明人： Miha Fuderer

IPC分类号： G01V300

CPC分类号： G01R33/5611 ,  G01R33/3415

摘要： Magnetic resonance imaging method and apparatus which employ multiple magnetic resonance signals from an array of multiple sensors or coils for the reconstruction of images. The method is used in fast dynamic MR imaging. Prior to formation of fast dynamic images, a normal magnetic resonance image with a full set of phase encoding steps is acquired for each sensor or coil. A subset of phase encoding trajectories is extracted commensurate with the phase encoding trajectories obtained by the fast dynamic imaging and an image is reconstructed from the subset. Subsequently, the signals of the fast dynamic image are compared with the signals of the reconstructed image, thus yielding an estimate of the fold-over artefacts of the fast dynamic image. The signals of the fold-over artefacts thus compensate the signals obtained by the fast dynamic imaging and deliver a corrected image without artefact parts.

摘要翻译： 磁共振成像方法和装置，其采用来自多个传感器或线圈阵列的多个磁共振信号来重建图像。 该方法用于快速动态MR成像。 在形成快速动态图像之前，针对每个传感器或线圈获取具有全套相位编码步骤的正常磁共振图像。 提取相位编码轨迹的子集，与通过快速动态成像获得的相位编码轨迹相称，并且从子集重建图像。 随后，将快速动态图像的信号与重建图像的信号进行比较，从而产生快速动态图像的折叠伪影的估计。 因此，折叠伪影的信号补偿了通过快速动态成像获得的信号，并且传递没有伪影部分的校正图像。

公开(公告)号：US06268729B1

公开(公告)日：2001-07-31

申请号：US09137373

申请日：1998-08-20

申请人： Miha Fuderer ,  Cornelis L. G. Ham ,  Joost M. De Haan ,  Johannes H. Den Boef

发明人： Miha Fuderer ,  Cornelis L. G. Ham ,  Joost M. De Haan ,  Johannes H. Den Boef

IPC分类号： G01V300

CPC分类号： G01R33/565

摘要： The invention relates to a method and a device for the imaging of a part of an object which is arranged in a steady magnetic field. The method according to the invention includes a step for filtering the shot noise from the measured MR signals. Filtering is performed by determining in a first step the value of a combination of a value of a parameter of a measuring point of the MR signal to be corrected and values of the parameter of measuring points in a vicinity of the measuring point. If the value of this combination exceeds a predetermined reference, the value zero is assigned to the value to be corrected. The invention is based on the idea that for a substantial part of the k space the corresponding MR signals behave as white noise. The reference is determined from the statistical distribution of the white noise. If the value of the combination exceeds the reference, it is assumed that a measuring point has been affected by shot noise.

摘要翻译： 本发明涉及一种用于成像被配置在稳定磁场中的物体的一部分的方法和装置。 根据本发明的方法包括从所测量的MR信号中滤波发射噪声的步骤。 通过在第一步骤中确定要校正的MR信号的测量点的参数的值与测量点附近的测量点的参数的值的组合来执行滤波。 如果该组合的值超过预定的参考值，则将零值分配给要校正的值。 本发明基于以下思想：对于k空间的大部分，相应的MR信号表现为白噪声。 参考是从白噪声的统计分布确定的。 如果组合的值超过参考值，则假定测量点受到喷射噪声的影响。

公开(公告)号：US5773975A

公开(公告)日：1998-06-30

申请号：US718807

申请日：1996-09-24

申请人： Jan F. L. De Becker ,  Thomas L. M. Hoogenboom ,  Miha Fuderer

发明人： Jan F. L. De Becker ,  Thomas L. M. Hoogenboom ,  Miha Fuderer

IPC分类号： G01N24/00 ,  A61B5/055 ,  G01R33/48 ,  G01R33/563 ,  G01V3/00

CPC分类号： G01R33/56308 ,  G01R33/56316

摘要： A method of determining a velocity of moving matter by magnetic resonance, includes a application of a phase contrast method in at least one measuring direction so as to determine a velocity. Upon determination of the velocity by means of phase contrast MRA, the cyclic nature of the phase introduces an ambiguity in the velocity determination. This ambiguity is removed by performing an additional measurement in an additional direction and by combining the velocity measured in the additional direction with the previously determined velocity. It has also been found that there is an optimum direction for this additional measurement. The advantage of the method of the invention is that the velocities can be determined and corrected in the three basic directions. As a result, low flow velocities can be determined and corrected in the three basic directions. As a result, low flow velocities can be measured, so that slow liquid flows in small blood vessels can be made visible in an MR image.

摘要翻译： 通过磁共振确定移动物体的速度的方法包括在至少一个测量方向上应用相位对比方法以确定速度。 在通过相位对比度MRA确定速度时，相位的循环特性在速度确定中引入了歧义。 通过在附加方向上执行额外的测量并且将在附加方向上测量的速度与先前确定的速度组合来消除这种模糊性。 还已经发现，对于该附加测量，存在最佳方向。 本发明的方法的优点在于可以在三个基本方向上确定和校正速度。 结果，可以在三个基本方向上确定和校正低流速。 结果，可以测量低流速，使得在MR图像中可以使在小血管中流动的液体缓慢。