公开(公告)号：USD482454S1

公开(公告)日：2003-11-18

申请号：US29167829

申请日：2002-09-20

Applicant: Peter Louis Gebrian

Designer： Peter Louis Gebrian

公开(公告)号：US06265374B1

公开(公告)日：2001-07-24

申请号：US09421845

申请日：1999-10-20

Applicant: Anders Jorgen Andersen ,  Roger Aston ,  Peter Louis Carlen ,  Penelope Reed Doob ,  Douglas Kevin MacFadden ,  David James Phipps ,  Deborah Rathjen ,  Fred Widmer

Inventor： Anders Jorgen Andersen ,  Roger Aston ,  Peter Louis Carlen ,  Penelope Reed Doob ,  Douglas Kevin MacFadden ,  David James Phipps ,  Deborah Rathjen ,  Fred Widmer

IPC: A61K3800

CPC classification number: C07K5/1013 ,  A61K38/08 ,  C07K14/005 ,  C12N2740/16122

Abstract: A method of treating inflammation in patients in need of such treatment by administering an effective amount of I-A-B-C-D-E-F-G-H-II (General Formula), wherein A is Ala, Gly, Val, Ser, Thr or absent, B is Ala, Gly, Val, Ser, Thr, or absent, C is Ser, Thr or absent, D is Ser, Thr, Asn, Glu, Arg, Ile, Leu or absent, E is Ser, Thr, Asp or absent, F is Ser, Thr, Asp or absent, G is Tyr or absent, H is Thr, Arg, Gly, Met, Met(O), Cys, Thr, Gly or absent and I is Cys or absent II is Cys, an amide group, an ester group or absent. At least one of the amino acids optionally is substituted by a monomeric or polymeric carbohydrate or derivative thereof, such substitution being accomplished through hydroxyl and/or amino acid and/or amido groups of the amino acids, and wherein the peptide composes at least 4 amino acid residues, and a pharmaceutically acceptable salt thereof.

Abstract translation: 通过施用有效量的IABCDEFGH-II（通式），其中A是Ala，Gly，Val，Ser，Thr或不存在，B是Ala，Gly，Val，Ser，治疗需要这种治疗的患者的炎症的方法 ，Thr或不存在，C为Ser，Thr或不存在，D为Ser，Thr，Asn，Glu，Arg，Ile，Leu或不存在，E为Ser，Thr，Asp或不存在，F为Ser，Thr，Asp或 不存在，G是Tyr或不存在，H是Thr，Arg，Gly，Met，Met（O），Cys，Thr，Gly或不存在，I是Cys或不存在II是Cys，酰胺基，酯基或不存在。 氨基酸中的至少一个任选被单体或聚合碳水化合物或其衍生物取代，这种取代通过氨基酸的羟基和/或氨基酸和/或酰胺基完成，并且其中肽组成至少4个氨基 酸残基及其药学上可接受的盐。

公开(公告)号：US06251942B1

公开(公告)日：2001-06-26

申请号：US09316203

申请日：1999-05-21

Applicant: Peter Louis Carlen ,  Christopher George Janus ,  Hossam El-Beheiry

Inventor： Peter Louis Carlen ,  Christopher George Janus ,  Hossam El-Beheiry

IPC: A61K31195

CPC classification number: A61K31/225 ,  A61K31/00 ,  A61K31/195 ,  A61K31/198 ,  Y10S424/06 ,  Y10S514/836

Abstract: Composition and methods of alleviating impaired mental function and memory loss in mammals and reducing the recovery time from anaesthesia in age mammals, comprising treating the mammal with a non-toxic, enhancing effective amount of a cell membrane permeant calcium buffer. The buffer is preferably a calcium ion chelating agent having a KD selected from the range 1×10−4 to 1×10−8 Molar and being essentially calcium ion-selective over other metal ions. A most preferred buffer is BAPTA-AM.

Abstract translation: 包括减轻哺乳动物的精神功能受损和记忆丧失的组合物和方法，并且减少哺乳动物年龄的麻醉的恢复时间，包括用无毒的增强有效量的细胞膜渗透性钙缓冲液治疗哺乳动物。 缓冲剂优选为具有选自1×10-4至1×10-8摩尔范围的KD的钙离子螯合剂，并且与其它金属离子基本上是钙离子选择性的。 最优选的缓冲液是BAPTA-AM。

公开(公告)号：US06024805A

公开(公告)日：2000-02-15

申请号：US968970

申请日：1997-11-12

Applicant: Young Jin Kim ,  Peter Louis Andresen ,  George Charles Sogoian

Inventor： Young Jin Kim ,  Peter Louis Andresen ,  George Charles Sogoian

IPC: C23C26/00 ,  C23F11/18 ,  G21C17/022 ,  C23C8/00

CPC classification number: G21C17/0225 ,  C23C26/00 ,  C23F11/185

Abstract: A method for reducing the corrosion potential of steel vessels and piping used in nuclear reactors, in particular steel vessels and piping carrying high temperature water and/or steam which has a concentration of oxygen therein. A metal hydride is added to the water, the hydrogen of such metal hydride combining with oxidizing agents, typically oxygen, present in the water to reduce the concentration of such oxidizing agents. In the preferred embodiment the metal of the metal hydride is a metal that is capable of reacting with oxygen to form a substantially non-water soluble and substantially electrically insulating compound on the surface of the steel, and in particular is one that may react with and become deposited or incorporated into a pre-existing thin oxide film layer on the surface of the steel to thereby render such thin oxide layer substantially non-electrically conducting.

Abstract translation: 一种用于降低核反应堆，特别是含有其中具有氧浓度的高温水和/或蒸汽的钢容器和管道的钢管和管道的腐蚀电位的方法。 将金属氢化物加入到水中，这种金属氢化物的氢与存在于水中的氧化剂（通常为氧）结合，以降低这种氧化剂的浓度。 在优选的实施方案中，金属氢化物的金属是能够与氧反应以在钢的表面上形成基本上非水溶性且基本上电绝缘的化合物的金属，特别是可与 变得沉积或并入到钢表面上的预先存在的薄氧化膜层中，从而使这种薄氧化层基本上不导电。

公开(公告)号：US5817419A

公开(公告)日：1998-10-06

申请号：US682870

申请日：1996-07-12

Applicant: Michael Fryd ,  Peter Louis Huesmann ,  Allan Harold Olson

Inventor： Michael Fryd ,  Peter Louis Huesmann ,  Allan Harold Olson

IPC: B32B27/30 ,  C08L33/06 ,  C09D127/12 ,  C09D127/18 ,  C09D133/02 ,  C09D133/10 ,  B32B27/28 ,  C08L27/12 ,  C08L27/18

CPC classification number: C09D127/12 ,  C09D127/18 ,  C08L33/06 ,  C08L33/064 ,  Y10T428/254 ,  Y10T428/3154 ,  Y10T428/31544 ,  Y10T428/31935

Abstract: An aqueous dispersion contains melt-fabricable fluoropolymer particles and acrylic copolymer particles, said acrylic copolymers having a decomposition temperature of less than 340.degree. C., wherein the dispersion contains about 75 to about 95 wt % of fluoropolymer and about 5 to about 25 wt % of acrylic copolymer, based on combined weights of the two polymers. Coated articles comprise a substrate coated with a primer layer, optional intermediate coats, and a topcoat with at least the topcoat being formed from the aqueous dispersion.

Abstract translation: 水分散体含有可熔融制造的含氟聚合物颗粒和丙烯酸共聚物颗粒，所述丙烯酸共聚物的分解温度低于340℃，其中分散体含有约75至约95重量％的含氟聚合物和约5至约25重量％ 的丙烯酸共聚物，基于两种聚合物的组合重量。 涂覆制品包括涂覆有底漆层的基材，任选的中间涂层和至少由水分散体形成的面漆的面漆。

公开(公告)号：US5673297A

公开(公告)日：1997-09-30

申请号：US509280

申请日：1995-07-31

Applicant: Peter Louis Andresen

Inventor： Peter Louis Andresen

IPC: G21D1/00 ,  C23F11/18 ,  C23F15/00 ,  G21C13/087 ,  G21C17/02 ,  G21C17/022 ,  G21C19/28 ,  G21D3/08 ,  G21C9/00

CPC classification number: G21C17/0225 ,  C23F15/00 ,  G21C13/087 ,  G21C19/28 ,  G21Y2002/104 ,  G21Y2004/20 ,  G21Y2004/304 ,  G21Y2004/403 ,  Y02E30/40

Abstract: A method for mitigating initiation or propagation of a crack in a surface of a metal component in a boiling water reactor. The method includes the step of injecting a solution or suspension of a pH-adjusting compound into the bulk water of the reactor. The compound has the property of changing the pH of high-temperature water inside the crack from a value outside a predetermined pH range (namely, pH 6.0 to 8.0) to a value within the predetermined pH range without causing any significant change of the bulk water pH. The growth rate of the crack when the crack pH is outside the predetermined pH range is greater than the growth rate of the crack when the crack pH is within the predetermined pH range.

Abstract translation: 一种用于减轻沸水反应器中金属组分表面中的裂纹的引发或扩散的方法。 该方法包括将pH调节化合物的溶液或悬浮液注入反应器的主体水中的步骤。 该化合物具有将裂纹内部的高温水的pH从规定的pH范围以外的值（即pH6.0〜8.0）变更为规定的pH范围内的值，而不会引起本体水的任何显着变化 pH值。 当裂纹pH在预定pH范围之外时，裂纹的生长速率大于裂纹pH在预定pH范围内时裂纹的生长速率。