公开(公告)号：US20060251761A1

公开(公告)日：2006-11-09

申请号：US11121170

申请日：2005-05-03

申请人： Robert Jansen ,  John Kerr ,  Edward Farley ,  Gordon Walker ,  Sebastien Camborieux

发明人： Robert Jansen ,  John Kerr ,  Edward Farley ,  Gordon Walker ,  Sebastien Camborieux

IPC分类号： A23L1/10

CPC分类号： C12Y302/00 ,  A23J1/125 ,  A23J3/18 ,  A23K10/30 ,  A23K20/179 ,  A23K50/80 ,  A23L7/104 ,  A23L29/35 ,  C13B20/142 ,  C13K1/08 ,  Y02A40/818

摘要： Whole grain, such as wheat, barley, rye, and/or rice, can be processed by (a) steeping the grain or at least partially dehulled grain in an aqueous liquid to produce softened grain, (b) milling the softened grain to produce milled grain, (c) liquefying the milled grain by contacting it with amylase and heating it to a temperature of at least about 50° C., producing a liquefied material, (d) at least partially saccharifying the liquefied material by contacting it with amyloglucosidase at a temperature of at least about 50° C., producing a first saccharified material, and (e) separating fiber and germ from the first saccharified material, producing a screened material that is substantially free of fiber and wheat germ. The process also includes the steps of (f) further saccharifying the screened material by contacting it with amyloglucosidase at a temperature of at least about 50° C., producing a second saccharified material, (g) membrane filtering the second saccharified material, producing a permeate that comprises primarily dextrose and other soluble components and a retentate that comprises insoluble protein, and (h) purifying the permeate by chromatographic separation, producing a purified dextrose stream. The chromatographic separation can also produce a raffinate, and the process can further include the steps of (i) combining the retentate from the membrane filtration and the raffinate from the chromatographic separation to form a fermentation medium, (j) fermenting the fermentation medium aerobically with a microorganism, (k) separating a protein product that comprises insoluble protein and microorganism from the medium, and (l) drying the protein product.

摘要翻译： 可以通过（a）在水性液体中浸渍颗粒或至少部分去壳的颗粒以产生软化的颗粒，（b）研磨软化的颗粒以产生（例如，麦粒，大麦，黑麦和/或米） （c）通过使其与淀粉酶接触并将其加热到至少约50℃的温度来液化所研磨的颗粒，产生液化材料，（d）通过使液化物质与淀粉葡糖苷酶接触而至少部分地糖化 在至少约50℃的温度下，产生第一糖化材料，和（e）从第一糖化物质分离纤维和胚芽，产生基本上不含纤维和小麦胚芽的筛选材料。 该方法还包括以下步骤：（f）通过使筛选的材料与淀粉葡糖苷酶在至少约50℃的温度下接触进一步糖化，产生第二糖化物质，（g）膜过滤第二糖化物质，产生 主要包含葡萄糖和其他可溶性组分的渗透物和包含不溶性蛋白质的渗余物，和（h）通过色谱分离纯化渗透物，产生纯化的葡萄糖流。 色谱分离还可以产生萃余液，并且该方法还可以包括以下步骤：（i）将来自膜过滤的残留物和来自色谱分离的萃余液组合以形成发酵培养基，（j）有氧地发酵发酵培养基， 微生物，（k）从培养基中分离含有不溶性蛋白质和微生物的蛋白质产物，和（l）干燥蛋白质产物。

公开(公告)号：US06305371B1

公开(公告)日：2001-10-23

申请号：US09117229

申请日：1998-07-24

申请人： Per Frid ,  Robert Jansen ,  Paul Wright

发明人： Per Frid ,  Robert Jansen ,  Paul Wright

IPC分类号： A61M1500

CPC分类号： A61M15/009 ,  A61M2205/6081

摘要： An inhaler for administering medicament by inhalation and a method of manufacturing a housing of the same, the inhaler including a housing formed as a single-piece moulding having a first portion (18) which, in normal use, comes into contact with medicament and the mouth or nose of a user through which medicament is inhaled and a second portion (20) which defines at least part of the outer surface of the housing and, in normal use, does not come into contact with medicament or the mouth or nose of a user through which medicament is inhaled, wherein the material constitution of at least part of the second portion (20) defining at least part of the outer surface of the housing is different to the material constitution of the first portion (18).

摘要翻译： 一种用于通过吸入给药药物的吸入器及其制造方法，所述吸入器包括形成为单件模制件的壳体，所述壳体具有在正常使用中与药物接触的第一部分（18）和 吸入药物的使用者的嘴或鼻子以及限定外壳的至少一部分外表面的第二部分（20），并且在正常使用中不与药物或嘴或鼻部接触 用户通过其吸入药物，其中限定外壳的外表面的至少一部分的第二部分（20）的至少一部分的材料构造与第一部分（18）的材料构造不同。