公开(公告)号：US11350899B2

公开(公告)日：2022-06-07

申请号：US17033136

申请日：2020-09-25

Applicant: Cleerly, Inc.

Inventor： James K. Min

IPC: A61B6/00 ,  A61B6/03 ,  G06T7/00

Abstract: A method for characterization of coronary plaque tissue data and perivascular tissue data using image data gathered from a computed tomography (CT) scan along a blood vessel, the image information including radiodensity values of coronary plaque and perivascular tissue located adjacent to the coronary plaque, the method comprising quantifying radiodensity in regions of coronary plaque, quantifying, radiodensity in at least one region of corresponding perivascular tissue adjacent to the coronary plaque, determining gradients of the quantified radiodensity values within the coronary plaque and the quantified radiodensity values within the corresponding perivascular tissue, and determining a ratio of the quantified radiodensity values within the coronary plaque and the corresponding perivascular tissue; and characterizing the coronary plaque by analyzing a gradient of the quantified radiodensity values in the coronary plaque and the corresponding perivascular, and/or the ratio of the coronary plaque radiodensity values and the radiodensity values of the corresponding perivascular tissue.

公开(公告)号：US11321840B2

公开(公告)日：2022-05-03

申请号：US17393881

申请日：2021-08-04

Applicant: CLEERLY, INC.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC: G06K9/00 ,  G06T7/00 ,  A61B5/055 ,  A61B6/03 ,  A61B8/14 ,  A61B8/12 ,  A61B5/00 ,  A61B6/00 ,  G06K9/62 ,  A61K49/04

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US11232564B2

公开(公告)日：2022-01-25

申请号：US17367562

申请日：2021-07-05

Applicant: CLEERLY, INC.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques ,  Ben Hootnick

IPC: G06K9/00 ,  G06T7/00 ,  A61B8/14 ,  A61B6/00 ,  A61B6/03 ,  A61B5/00 ,  A61B8/12 ,  G06K9/62 ,  A61B5/055 ,  A61K49/04

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US11094060B1

公开(公告)日：2021-08-17

申请号：US17213966

申请日：2021-03-26

Applicant: CLEERLY, INC.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC: G06K9/00 ,  G06T7/00 ,  A61B8/14 ,  A61B6/00 ,  A61B6/03 ,  A61B5/00 ,  A61B8/12 ,  G06K9/62 ,  A61B5/055 ,  A61K49/04

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US20250120666A1

公开(公告)日：2025-04-17

申请号：US18940602

申请日：2024-11-07

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC: A61B6/50 ,  A61B5/00 ,  A61B5/055 ,  A61B6/00 ,  A61B6/03 ,  A61B6/46 ,  A61B8/12 ,  A61B8/14 ,  A61K49/04 ,  G06F18/10 ,  G06T7/00 ,  G06V10/20 ,  G06V10/24 ,  G06V10/74 ,  G06V10/764 ,  G06V10/82

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US12245882B2

公开(公告)日：2025-03-11

申请号：US18612980

申请日：2024-03-21

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques ,  Ben Hootnick

IPC: A61B6/04 ,  A61B5/00 ,  A61B5/02 ,  A61B5/055 ,  A61B6/00 ,  A61B6/03 ,  A61B6/50 ,  A61B8/12 ,  A61B8/14 ,  A61K49/04 ,  G06T7/00 ,  G06V10/20 ,  G06V10/24 ,  G06V10/74 ,  G06V10/764 ,  G06V40/14

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US20250000472A1

公开(公告)日：2025-01-02

申请号：US18591778

申请日：2024-02-29

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  Hugo Miguel Rodrigues Margues

IPC: A61B6/00 ,  A61B6/03 ,  A61B6/50 ,  G06T7/00 ,  G06T7/62 ,  G06V10/22 ,  G06V10/26 ,  G16H30/40 ,  G16H50/20

Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.

公开(公告)号：US12178627B2

公开(公告)日：2024-12-31

申请号：US18641232

申请日：2024-04-19

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC: G06V10/74 ,  A61B5/00 ,  A61B5/055 ,  A61B6/00 ,  A61B6/03 ,  A61B6/46 ,  A61B6/50 ,  A61B8/12 ,  A61B8/14 ,  A61K49/04 ,  G06F18/10 ,  G06T7/00 ,  G06V10/20 ,  G06V10/24 ,  G06V10/764 ,  G06V10/82

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US20240423573A1

公开(公告)日：2024-12-26

申请号：US18593121

申请日：2024-03-01

Applicant: Cleerly, Inc.

Inventor： James K. Min

IPC: A61B6/00 ,  A61B6/03 ,  A61B6/50 ,  G06T7/00 ,  G06T7/62 ,  G06V10/22 ,  G06V10/26 ,  G16H30/40 ,  G16H50/20

Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.

公开(公告)号：US12156759B2

公开(公告)日：2024-12-03

申请号：US18629673

申请日：2024-04-08

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC: G06V10/74 ,  A61B5/00 ,  A61B5/055 ,  A61B6/00 ,  A61B6/03 ,  A61B6/46 ,  A61B6/50 ,  A61B8/12 ,  A61B8/14 ,  A61K49/04 ,  G06F18/10 ,  G06T7/00 ,  G06V10/20 ,  G06V10/24 ,  G06V10/764 ,  G06V10/82

Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.