Patent search ap:("FORMA Therapeutics Page Inc.") AND inv:"Jennifer R. Thomason"

61.

发明申请
3-ARYL-4-AMIDO-BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS 审中-公开
Title translation: 3-ARYL-4-AMIDO-BICYCLIC [4,5,0]氢氧化物作为HDAC抑制剂

公开(公告)号：US20160222022A1

公开(公告)日：2016-08-04

申请号：US15013816

申请日：2016-02-02

Applicant: Forma Therapeutics, Inc.

Inventor： Xiaozhang Zheng , Pui Yee Ng , Bingsong Han , Jennifer R. Thomason , Mary-Margaret Zablocki , Cuixian Liu , Heather Davis , Aleksandra Rudnitskaya , David Lancia, JR. , David S. Millan , Matthew W. Martin

IPC: C07D493/08 , C07D267/14 , C07D413/14 , C07D413/06

CPC classification number: C07D267/14 , C07D243/14 , C07D267/12 , C07D291/08 , C07D401/06 , C07D401/10 , C07D403/06 , C07D403/10 , C07D405/06 , C07D413/04 , C07D413/06 , C07D413/08 , C07D413/12 , C07D413/14 , C07D417/04 , C07D471/04 , C07D491/107 , C07D493/08 , C07D495/10 , C07D498/04 , C07D498/08

Abstract: The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I: where R, L, X1, X2, X3, X4, Y1, Y2, Y3, and Y4 are described herein.

Abstract translation: 本公开涉及可用于治疗与HDAC相关的疾病或病症的锌依赖性组蛋白脱乙酰酶（HDAC）的抑制剂，例如具有式I的HDAC6：其中R，L，X 1，X 2，X 3，X 4， Y1，Y2，Y3和Y4。

62.

发明申请
3-ARYL BICYCLIC [4,5,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS 审中-公开
Title translation: 3-ARYL BICYCLIC [4,5,0]氢氧化物作为HDAC抑制剂

公开(公告)号：US20160221973A1

公开(公告)日：2016-08-04

申请号：US15013826

申请日：2016-02-02

Applicant: Forma Therapeutics, Inc.

Inventor： Xiaozhang Zheng , Pui Yee Ng , Bingsong Han , Jennifer R. Thomason , Mary-Margaret Zablocki , Cuixian Liu , Aleksandra Rudnitskaya , David Lancia, JR. , David S. Millan , Matthew W. Martin

IPC: C07D267/14 , C07D413/12 , C07D413/04 , C07D413/06

CPC classification number: C07D267/14 , C07D243/14 , C07D267/12 , C07D291/08 , C07D401/06 , C07D401/10 , C07D403/06 , C07D403/10 , C07D405/06 , C07D413/04 , C07D413/06 , C07D413/08 , C07D413/12 , C07D413/14 , C07D417/04 , C07D471/04 , C07D491/107 , C07D493/08 , C07D495/10 , C07D498/04 , C07D498/08

Abstract: The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formula I: where R, L, X1, X2, X3, X4, Y1, Y2, Y3, and Y4 are described herein.

Abstract translation: 本发明涉及可用于治疗与HDAC6相关的疾病或病症的锌依赖性组蛋白脱乙酰酶（HDAC）的抑制剂，其具有式I：其中R，L，X 1，X 2，X 3，X 4，Y 1，Y 2，Y 3 ，和Y4。

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