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公开(公告)号:US20050065169A1
公开(公告)日:2005-03-24
申请号:US10850429
申请日:2004-05-21
申请人: Weibo Wang , Liana Lagniton , Ryan Constantine , Matthew Burger
发明人: Weibo Wang , Liana Lagniton , Ryan Constantine , Matthew Burger
IPC分类号: A61K31/519 , A61P35/00 , C07D487/02 , C07D495/04
CPC分类号: C07D239/88 , C07D495/04 , Y10S435/81
摘要: Heteroaryl-fused pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the heteroaryl-fused pyrimidinyl compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.
摘要翻译: 杂芳基稠合的嘧啶基化合物,其药学上可接受的盐和前药; 包括药学上可接受的载体和一种或多种杂芳基稠合的嘧啶基化合物的组合物,单独或与至少一种另外的治疗剂组合。 将杂芳基稠合的嘧啶基化合物单独使用或与至少一种另外的治疗剂组合使用在预防或治疗增殖性疾病中的方法。