公开(公告)号：US20100023024A1

公开(公告)日：2010-01-28

申请号：US12179598

申请日：2008-07-25

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Lawrence Crainich ,  Alex P. Kondor

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Lawrence Crainich ,  Alex P. Kondor

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0493 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/003 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/292 ,  A61B2017/2923

摘要： A reloadable device for deploying fasteners. The device has a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The device also includes a means, adjacent the handle, for facilitating removal of the first cartridge from the handle and replacing it with a second cartridge.

摘要翻译： 用于部署紧固件的可重装装置。 该装置具有手柄和至少一个致动器。 手柄连接到具有远端和近端的细长的中空壳体。 该装置具有容纳可释放地连接到手柄的至少一个紧固件的第一盒。 紧固件具有至少两个通过非弹性柔性缝合线连接在一起的锚固件，其在可压缩载荷下不会抵抗变形。 该装置还包括与手柄相邻的装置，以便于将第一盒从手柄移除并用第二盒替换。

公开(公告)号：US20090275964A1

公开(公告)日：2009-11-05

申请号：US12113773

申请日：2008-05-01

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Daniel E. Alesi ,  Mark S. Ortiz ,  Thomas E. Albrecht ,  James T. Spivey ,  Lawrence Crainich

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Daniel E. Alesi ,  Mark S. Ortiz ,  Thomas E. Albrecht ,  James T. Spivey ,  Lawrence Crainich

IPC分类号： A61B17/12 ,  A61B17/34

CPC分类号： A61B17/00234 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/0649 ,  A61B2017/081 ,  A61B2017/2926 ,  A61F5/0086

摘要： A rolling instrument for rolling the outside surface of the stomach for reducing stomach volume in bariatric surgery includes an elongated tubular body that is sufficiently flexible to allow for access to the outside surface. The tubular body includes a proximal end and a distal end. The proximal end is shaped and dimensioned for use by the medical practitioner performing the medical procedure and includes a handle for manipulation of the rolling instrument. The distal end of the tubular body includes a mechanism allowing for gripping of the stomach in a manner permitting rolling thereof. A coiled retainer shaped and dimensioned is provided for application to the rolled portion of the stomach in a manner holding the rolled portion of the stomach in its rolled configuration. The coiled retainer includes a helically coiled body having a first end and a second end, the first end is pointed such that it may puncture tissue as the coiled body is rotated during its application to the stomach.

摘要翻译： 用于在减肥手术中滚动用于减少胃体积的胃的外表面的滚动仪器包括具有足够柔性以允许进入外表面的细长管状体。 管状体包括近端和远端。 近端的形状和尺寸被医生执行医疗程序所使用，并且包括用于操纵滚动仪器的手柄。 管状体的远端包括允许以允许其滚动的方式夹持胃的机构。 提供成形和尺寸的盘形保持器，以使其处于卷成形状的胃的卷绕部分的方式施加到胃的卷绕部分。 卷绕的保持器包括具有第一端和第二端的螺旋状卷绕体，第一端是尖的，使得当线圈体在其施加到胃部期间旋转时可能刺穿组织。

公开(公告)号：US20120165793A1

公开(公告)日：2012-06-28

申请号：US12976745

申请日：2010-12-22

申请人： Mark S. Ortiz ,  Christopher J. Hess ,  Jason L. Harris ,  James T. Spivey ,  Michael J. Stokes ,  Thomas E. Albrecht ,  James W. Voegele ,  William B. Weisenburgh, II ,  Rudolph H. Nobis ,  Mark S. Zeiner ,  Mark D. Overmyer ,  Darrel M. Powell ,  Joseph Bernard Kraimer ,  James Anthony Topich ,  Jeremy David Jarrett ,  Daniel James Prenger ,  Matthew D. Rohr Daniel

发明人： Mark S. Ortiz ,  Christopher J. Hess ,  Jason L. Harris ,  James T. Spivey ,  Michael J. Stokes ,  Thomas E. Albrecht ,  James W. Voegele ,  William B. Weisenburgh, II ,  Rudolph H. Nobis ,  Mark S. Zeiner ,  Mark D. Overmyer ,  Darrel M. Powell ,  Joseph Bernard Kraimer ,  James Anthony Topich ,  Jeremy David Jarrett ,  Daniel James Prenger ,  Matthew D. Rohr Daniel

IPC分类号： A61K9/22

CPC分类号： A61M31/002 ,  A61B1/041

摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.

摘要翻译： 提供了设备和相关方法，用于将治疗剂控制递送到身体内的目标位置。 更具体地，提供了用于控制经口给药的药丸通过身体的速率的方法和装置，以及用于控制体内在特定位置处的丸剂内的治疗剂的递送。 提供了在本文中通常被称为“捕获器”的各种类型的装置，其可以在通过身体时主动地捕捉药丸。 捕获器可以将药丸保持在体内的特定位置，直到发生预定事件，例如在丸中部分或完全施用治疗剂。 然后，捕手可以在命令和/或发生预定事件时释放药片以允许药丸从身体中流出。 在其他实施例中，提供了可以主动地接合捕获器并保持与捕获器接合的各种类型的药丸，直到发生预定事件。

公开(公告)号：US20120080495A1

公开(公告)日：2012-04-05

申请号：US13325536

申请日：2011-12-14

申请人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Mark S. Ortiz ,  Alexander P. Kondor ,  Lawrence Crainich ,  Eugene L. Timperman

发明人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Mark S. Zeiner ,  Mark S. Ortiz ,  Alexander P. Kondor ,  Lawrence Crainich ,  Eugene L. Timperman

IPC分类号： A61B17/068

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/2917 ,  A61B2017/292 ,  A61B2017/2923 ,  A61B2017/2926

摘要： A device for deploying fasteners including a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device has a first cartridge containing at least one fastener releasably connectable to the handle. The device also includes an elongated pusher movable through the hollow housing from the proximal to the distal end to deploy the fasteners. The device further includes a deforming member for deforming the pusher at a proximal end thereof while advancing the pusher to the distal end of the housing.

摘要翻译： 一种用于展开紧固件的装置，包括手柄和至少一个致动器。 手柄连接到具有远端和近端的细长的中空壳体。 该装置具有容纳可释放地连接到手柄的至少一个紧固件的第一盒。 该装置还包括细长的推动器，其可从近端到远端移动穿过中空壳体以展开紧固件。 该装置还包括变形构件，用于使推动器在其近端处变形，同时将推动器推进到壳体的远端。

公开(公告)号：US20100023026A1

公开(公告)日：2010-01-28

申请号：US12179605

申请日：2008-07-25

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Lawrence Crainich ,  Alex P. Kondor

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Lawrence Crainich ,  Alex P. Kondor

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0493 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/292 ,  A61B2017/2923

摘要： A reloadable device for deploying fasteners. The device has a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends. The device includes a first cartridge containing at least one fastener releasably connectable to the handle. The fastener has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The first cartridge is removable from the handle. The device includes a second cartridge having at least one fastener releasably connectable to the handle after removal of the first cartridge. The second cartridge being insertable into the device from a proximal end thereof.

摘要翻译： 用于部署紧固件的可重装装置。 该装置具有手柄和至少一个致动器。 手柄连接到具有远端和近端的细长的中空壳体。 该装置包括容纳可释放地连接到手柄的至少一个紧固件的第一盒。 紧固件具有至少两个通过非弹性柔性缝合线连接在一起的锚固件，其在可压缩载荷下不会抵抗变形。 第一个墨盒可从手柄上取下。 该装置包括具有至少一个紧固件的第二盒，该至少一个紧固件在移除第一盒之后可释放地连接到手柄。 第二盒可从其近端插入到装置中。

公开(公告)号：US20100023025A1

公开(公告)日：2010-01-28

申请号：US12179600

申请日：2008-07-25

申请人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Eugene L. Timperman ,  Alex P. Kondor

发明人： Mark S. Zeiner ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Mark S. Ortiz ,  Eugene L. Timperman ,  Alex P. Kondor

IPC分类号： A61B17/10

CPC分类号： A61B17/0401 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0493 ,  A61B17/3498 ,  A61B90/92 ,  A61B90/94 ,  A61B2017/003 ,  A61B2017/00477 ,  A61B2017/00526 ,  A61B2017/0053 ,  A61B2017/00818 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/2916 ,  A61B2017/292 ,  A61B2017/2923 ,  A61F5/0086

摘要： A method of deploying fasteners within a body by providing a device having a handle and at least one actuator. The handle is connected to an elongated hollow housing having distal and proximal ends, and a needle within the hollow housing. The device has a first cartridge containing at least one fastener releasably connectable to the distal end of the hollow housing. The fastener is at least partially housed within the needle and has at least two anchors connected together by a non-resilient flexible suture which does not resist deformation under compressible loads. The method uses the steps of inserting the distal end of the hollow housing to a target site within a body, attaching tissue together within the body by deploying the fastener, and removing the first cartridge and replacing it with a second cartridge.

摘要翻译： 一种通过提供具有手柄和至少一个致动器的装置在身体内部署紧固件的方法。 手柄连接到具有远端和近端的细长的中空壳体，以及在中空壳体内的针。 该装置具有第一盒，该第一盒包含至少一个可释放地连接到中空壳体的远端的紧固件。 紧固件至少部分地容纳在针内，并且具有至少两个锚固件，其通过非弹性柔性缝合线连接在一起，其在可压缩载荷下不会抵抗变形。 该方法使用以下步骤：将中空壳体的远端插入到体内的目标部位，通过展开紧固件将组织连接在体内，并且移除第一盒并用第二盒替换。

公开(公告)号：US08727964B2

公开(公告)日：2014-05-20

申请号：US12562279

申请日：2009-09-18

申请人： Daniel F. Dlugos, Jr. ,  Thomas E. Adams ,  Randal T. Byrum ,  Sean P. Conlon ,  Rocco Crivelli ,  Dean L. Garner ,  Alec J. Ginggen ,  Wells D. Haberstich ,  Geoffrey C. Hueil ,  Donna L. Korvick ,  David T. Krumanaker ,  Timothy P. Lessek ,  Amy L. Marcotte ,  Jeffrey D. Messerly ,  Kyle P. Moore ,  Daniel J. Mumaw ,  Anil K. Nalagatla ,  Mark S. Ortiz ,  Frederick E. Shelton, IV ,  Bret W. Smith ,  Jeffrey S. Swayze ,  Patrick J. Swindon ,  Eric W. Thompson ,  Mark Tsonton ,  Lauren S. Weaner ,  Christopher W. Widenhouse ,  Scott A. Woodruff

发明人： Daniel F. Dlugos, Jr. ,  Thomas E. Adams ,  Randal T. Byrum ,  Sean P. Conlon ,  Rocco Crivelli ,  Dean L. Garner ,  Alec J. Ginggen ,  Wells D. Haberstich ,  Geoffrey C. Hueil ,  Donna L. Korvick ,  David T. Krumanaker ,  Timothy P. Lessek ,  Amy L. Marcotte ,  Jeffrey D. Messerly ,  Kyle P. Moore ,  Daniel J. Mumaw ,  Anil K. Nalagatla ,  Mark S. Ortiz ,  Frederick E. Shelton, IV ,  Bret W. Smith ,  Jeffrey S. Swayze ,  Patrick J. Swindon ,  Eric W. Thompson ,  Mark Tsonton ,  Lauren S. Weaner ,  Christopher W. Widenhouse ,  Scott A. Woodruff

IPC分类号： A61F2/00 ,  A61F13/00

CPC分类号： A61F5/0053 ,  A61F2/0036 ,  A61F5/003 ,  A61F5/0033 ,  A61F5/0056 ,  A61F5/0059

摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. The elongated member has a compressible ventral surface and a substantially rigid dorsal periphery, wherein the elongated member includes a fluid bladder positioned along the ventral surface. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. Alternate embodiments are also disclosed.

摘要翻译： 用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。 细长构件具有可压缩的腹侧表面和基本刚性的背侧周边，其中细长构件包括沿腹侧面定位的流体囊。 紧固件设置在细长构件的第一端上。 紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。 张力元件设置成在细长构件内移动。 驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。 还公开了替代实施例。

公开(公告)号：US20090157113A1

公开(公告)日：2009-06-18

申请号：US11958638

申请日：2007-12-18

申请人： Amy L. Marcotte ,  Thomas E. Albrecht ,  Daniel F. Dlugos, JR. ,  Mark S. Ortiz

发明人： Amy L. Marcotte ,  Thomas E. Albrecht ,  Daniel F. Dlugos, JR. ,  Mark S. Ortiz

IPC分类号： A61M29/00

CPC分类号： A61F5/0059 ,  A41D13/1245 ,  A41D13/1281

摘要： Various wearable elements are provided for a more comfortable and efficient way of carrying external devices related to powering and monitoring an implantable restriction device. In one exemplary embodiment, a system for forming a restriction in a patient is provided and includes an implantable restriction device adapted to form a restriction in a patient and having an implantable communicating member configured to send and/or receive a wireless signal. The system can further include a wearable element configured to be worn by a patient and an external device coupled to the wearable element which is configured to send and/or receive a wireless signal to communicate with the implantable communicating member.

摘要翻译： 提供各种可穿戴元件以便更舒适和有效地携带与驱动和监测可植入的限制装置相关的外部装置的方式。 在一个示例性实施例中，提供了一种用于在患者体内形成限制的系统，并且包括可植入的限制装置，其适于在患者体内形成限制并且具有配置成发送和/或接收无线信号的可植入通信部件。 该系统还可以包括被配置为由患者佩戴的可穿戴元件和耦合到可穿戴元件的外部设备，其被配置为发送和/或接收无线信号以与可植入通信构件通信。

公开(公告)号：US08523885B2

公开(公告)日：2013-09-03

申请号：US12562257

申请日：2009-09-18

申请人： Daniel F. Dlugos, Jr. ,  Wells D. Haberstich ,  Geoffrey C. Hueil ,  Donna L. Korvick ,  Jeffrey D. Messerly ,  Kyle P. Moore ,  Daniel J. Mumaw ,  Mark S. Ortiz ,  Frederick E. Shelton, IV ,  Patrick J. Swindon ,  Eric W. Thompson ,  Lauren S. Weaner

发明人： Daniel F. Dlugos, Jr. ,  Wells D. Haberstich ,  Geoffrey C. Hueil ,  Donna L. Korvick ,  Jeffrey D. Messerly ,  Kyle P. Moore ,  Daniel J. Mumaw ,  Mark S. Ortiz ,  Frederick E. Shelton, IV ,  Patrick J. Swindon ,  Eric W. Thompson ,  Lauren S. Weaner

IPC分类号： A61B17/12

CPC分类号： A61F5/0059 ,  A61F2/0036 ,  A61F5/003 ,  A61F5/0056

摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A load monitor ensures that excessive pressure is not applied to a patient's body organ or duct.

摘要翻译： 用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。 紧固件设置在细长构件的第一端上。 紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。 张力元件设置成在细长构件内移动。 驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。 负载监视器确保不会对患者的身体器官或管道施加过大的压力。

公开(公告)号：US20110071558A1

公开(公告)日：2011-03-24

申请号：US12562267

申请日：2009-09-18

申请人： Daniel F. Dlugos, JR. ,  Randal T. Byrum ,  Toralf Bork ,  Rocco Crivelli ,  Dean L. Garner ,  Alec J. Ginggen ,  Geoffrey C. Hueil ,  Donna L. Korvick ,  David T. Krumanaker ,  Amy L. Marcotte ,  Jeffrey D. Messerly ,  Kyle P. Moore ,  Daniel J. Mumaw ,  Anil K. Nalagatla ,  Mark S. Ortiz ,  Frederick E. Shelton, IV ,  Bret W. Smith ,  Jeffrey S. Swayze ,  Patrick J. Swindon ,  Richard W. Timm ,  Eric W. Thompson ,  Lauren S. Weaner

发明人： Daniel F. Dlugos, JR. ,  Randal T. Byrum ,  Toralf Bork ,  Rocco Crivelli ,  Dean L. Garner ,  Alec J. Ginggen ,  Geoffrey C. Hueil ,  Donna L. Korvick ,  David T. Krumanaker ,  Amy L. Marcotte ,  Jeffrey D. Messerly ,  Kyle P. Moore ,  Daniel J. Mumaw ,  Anil K. Nalagatla ,  Mark S. Ortiz ,  Frederick E. Shelton, IV ,  Bret W. Smith ,  Jeffrey S. Swayze ,  Patrick J. Swindon ,  Richard W. Timm ,  Eric W. Thompson ,  Lauren S. Weaner

IPC分类号： A61B17/122 ,  A61F2/04

CPC分类号： A61F5/0053 ,  A61F2/0036 ,  A61F5/003 ,  A61F5/0056 ,  A61F5/0059

摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A tension release mechanism is associated with the tension element.

摘要翻译： 用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。 紧固件设置在细长构件的第一端上。 紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。 张力元件设置成在细长构件内移动。 驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。 张力释放机构与张力元件相关联。