公开(公告)号：US5674433A

公开(公告)日：1997-10-07

申请号：US519125

申请日：1995-08-24

申请人： Michael J. Semmens ,  Charles J. Gantzer ,  Michael J. Bonnette

发明人： Michael J. Semmens ,  Charles J. Gantzer ,  Michael J. Bonnette

IPC分类号： B01F3/04

CPC分类号： B01F3/04241 ,  B01F3/04269 ,  B01F2003/04319 ,  Y10S261/75

摘要： An aeration device disperses microbubbles into a liquid and maintains efficient transfer of gas to the liquid. The aeration device uses a number of sealed end, hollow fiber membranes that are hydrophobic and provided with pores in the walls of the tubular fibers that range from about 0.01 to 1.0 microns, so that very small bubbles are formed on the outside surface of the hollow fiber membranes. Gas pressures above the bubble point of the fiber membranes are used, and a cloud of microbubbles is expelled into the liquid as it is forced to flow past the fibers. These microbubbles provide a large surface area for the effective dissolution of gases into the liquid. The length of the hollow fiber membranes is controlled in order to obtain efficient small bubble formation.

摘要翻译： 曝气装置将微泡分散在液体中并保持气体有效转移到液体中。 曝气装置使用多个密封端的中空纤维膜，其是疏水性的并且在管状纤维的壁中具有范围为约0.01至1.0微米的孔，使得在中空的外表面上形成非常小的气泡 纤维膜。 使用高于纤维膜泡点的气体压力，并且当其被迫流过纤维时，微泡云被排出到液体中。 这些微泡为气体有效溶解到液体中提供了大的表面积。 控制中空纤维膜的长度以获得有效的小气泡形成。

公开(公告)号：US06755803B1

公开(公告)日：2004-06-29

申请号：US09888455

申请日：2001-06-25

申请人： Hieu V. Le ,  Michael J. Bonnette ,  John Edward Morris ,  Stephen E. Weisel ,  Debra M. Kozak ,  Robert G. Dutcher

发明人： Hieu V. Le ,  Michael J. Bonnette ,  John Edward Morris ,  Stephen E. Weisel ,  Debra M. Kozak ,  Robert G. Dutcher

IPC分类号： A61B1720

CPC分类号： A61B17/32037 ,  A61B2090/034 ,  Y10T83/0443 ,  Y10T83/0453

摘要： A single operator exchange fluid jet thrombectomy device having an outer catheter assembly and separable and exchangeable components in the form of an inner catheter assembly allowing functioning as a rheolytic thrombectomy catheter or as a crossflow thrombectomy catheter. Embodiments include an outer catheter assembly common to any mode of usage having a guide catheter having a lumen through which a guidewire and the greater portion of a hypo-tube carrying a flow director are passed and advanced. For use as a rheolytic thrombectomy catheter, thrombus is dislodged, entrained, and broken into pieces by jets and evacuated through the lumen of the guide catheter. For use as a crossflow thrombectomy catheter, a flow director having outflow and inflow orifices is provided.

摘要翻译： 单个操作者交换流体喷射血栓切除装置，其具有外导管组件和内导管组件形式的可分离和可更换组件，其允许作为溶血性血栓切除术导管或横流血栓切除术导管。 实施例包括与任何使用模式共同的外导管组件，其具有具有内腔的引导导管，引导线和携带导流器的下管的较大部分通过该内腔通过并前进。 为了用作溶解性血栓切除术导管，血栓被移出，夹带并通过射流破碎成碎片，并通过导管的内腔排出。 为了用作横流血栓切除术导管，提供了具有流出和流入孔的导流器。